BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 36328089)

  • 1. The intricate interplay between HIFs, ROS, and the ubiquitin system in the tumor hypoxic microenvironment.
    Wang Y; Liu X; Huang W; Liang J; Chen Y
    Pharmacol Ther; 2022 Dec; 240():108303. PubMed ID: 36328089
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Protein Ubiquitination and HIF Signaling in the Evolution of Hypoxic Breast Cancer.
    Ray SK; Mukherjee S
    Curr Pharm Biotechnol; 2024 Feb; ():. PubMed ID: 38409721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of E3 Ligases and Deubiquitinases in the Control of HIF-α Subunit Abundance.
    Kubaichuk K; Kietzmann T
    Cells; 2019 Jun; 8(6):. PubMed ID: 31208103
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DUBs, Hypoxia, and Cancer.
    Mennerich D; Kubaichuk K; Kietzmann T
    Trends Cancer; 2019 Oct; 5(10):632-653. PubMed ID: 31706510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road.
    Günter J; Ruiz-Serrano A; Pickel C; Wenger RH; Scholz CC
    Exp Cell Res; 2017 Jul; 356(2):152-159. PubMed ID: 28315321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein.
    Groulx I; Lee S
    Mol Cell Biol; 2002 Aug; 22(15):5319-36. PubMed ID: 12101228
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia-inducible factor 1alpha, leading to its oxygen-independent degradation.
    Koh MY; Darnay BG; Powis G
    Mol Cell Biol; 2008 Dec; 28(23):7081-95. PubMed ID: 18838541
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    Miller F; Kentsis A; Osman R; Pan ZQ
    J Biol Chem; 2005 Mar; 280(9):7985-96. PubMed ID: 15611064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases.
    Paltoglou S; Roberts BJ
    Oncogene; 2007 Jan; 26(4):604-9. PubMed ID: 16862177
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-TrCP upregulates HIF-1 in prostate cancer cells.
    Cohen M; Amir S; Golan M; Ben-Neriah Y; Mabjeesh NJ
    Prostate; 2019 Mar; 79(4):403-413. PubMed ID: 30488478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the Ubiquitin Signaling Cascade in Tumor Microenvironment for Cancer Therapy.
    Liu Q; Aminu B; Roscow O; Zhang W
    Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33466790
    [TBL] [Abstract][Full Text] [Related]  

  • 12. K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.
    Wu HT; Kuo YC; Hung JJ; Huang CH; Chen WY; Chou TY; Chen Y; Chen YJ; Chen YJ; Cheng WC; Teng SC; Wu KJ
    Nat Commun; 2016 Dec; 7():13644. PubMed ID: 27934968
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
    Cassavaugh JM; Hale SA; Wellman TL; Howe AK; Wong C; Lounsbury KM
    J Cell Biochem; 2011 Dec; 112(12):3882-90. PubMed ID: 21964756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DUBs, New Members in the Hypoxia Signaling clUb.
    Schober AS; Berra E
    Front Oncol; 2016; 6():53. PubMed ID: 27014628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cbx4 governs HIF-1α to involve in Th9 cell differentiation promoting asthma by its SUMO E3 ligase activity.
    Huang W; Yu C; Wu H; Liang S; Kang J; Zhou Z; Liu A; Liu L
    Biochim Biophys Acta Mol Cell Res; 2023 Oct; 1870(7):119524. PubMed ID: 37348765
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer.
    Satija YK; Bhardwaj A; Das S
    Int J Cancer; 2013 Dec; 133(12):2759-68. PubMed ID: 23436247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.
    Queisser MA; Dada LA; Deiss-Yehiely N; Angulo M; Zhou G; Kouri FM; Knab LM; Liu J; Stegh AH; DeCamp MM; Budinger GR; Chandel NS; Ciechanover A; Iwai K; Sznajder JI
    Am J Respir Crit Care Med; 2014 Sep; 190(6):688-98. PubMed ID: 25118570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deubiquitinases in cancer.
    Dewson G; Eichhorn PJA; Komander D
    Nat Rev Cancer; 2023 Dec; 23(12):842-862. PubMed ID: 37935888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitination is absolutely required for the degradation of hypoxia-inducible factor--1 alpha protein in hypoxic conditions.
    Wang R; Zhang P; Li J; Guan H; Shi G
    Biochem Biophys Res Commun; 2016 Jan; 470(1):117-122. PubMed ID: 26766791
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pVHL-hIF-1 system. A key mediator of oxygen homeostasis.
    Maxwell PH; Pugh CW; Ratcliffe PJ
    Adv Exp Med Biol; 2001; 502():365-76. PubMed ID: 11950150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.