124 related articles for article (PubMed ID: 36336203)
1. Sex-specific effects of excipients on oral drug bioavailability.
Mai Y; Madla CM; Shao H; Qin Y; Merchant HA; Murdan S; Basit AW
Int J Pharm; 2022 Dec; 629():122365. PubMed ID: 36336203
[TBL] [Abstract][Full Text] [Related]
2. Modulation of Intestinal Transport and Absorption of Topotecan, a BCRP Substrate, by Various Pharmaceutical Excipients and Their Inhibitory Mechanisms of BCRP Transporter.
Sawangrat K; Yamashita S; Tanaka A; Morishita M; Kusamori K; Katsumi H; Sakane T; Yamamoto A
J Pharm Sci; 2019 Mar; 108(3):1315-1325. PubMed ID: 30389568
[TBL] [Abstract][Full Text] [Related]
3. Prandial state and biological sex modulate clinically relevant efflux transporters to different extents in Wistar and Sprague Dawley rats.
Gavins FKH; Dou L; Qin Y; Madla CM; Murdan S; Basit AW; Mai Y; Orlu M
Biomed Pharmacother; 2023 Apr; 160():114329. PubMed ID: 36731343
[TBL] [Abstract][Full Text] [Related]
4. Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animal.
Mai Y; Afonso-Pereira F; Murdan S; Basit AW
Eur J Pharm Sci; 2017 Sep; 107():249-255. PubMed ID: 28709912
[TBL] [Abstract][Full Text] [Related]
5. Sex-Dependence in the Effect of Pharmaceutical Excipients: Polyoxyethylated Solubilising Excipients Increase Oral Drug Bioavailability in Male but not Female Rats.
Mai Y; Dou L; Madla CM; Murdan S; Basit AW
Pharmaceutics; 2019 May; 11(5):. PubMed ID: 31083453
[TBL] [Abstract][Full Text] [Related]
6. Sex-specific and concentration-dependent influence of Cremophor RH 40 on ampicillin absorption via its effect on intestinal membrane transporters in rats.
Yin H; Shao H; Liu J; Qin Y; Deng W
PLoS One; 2022; 17(2):e0263692. PubMed ID: 35226682
[TBL] [Abstract][Full Text] [Related]
7. The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison.
Weinheimer M; Fricker G; Burhenne J; Mylius P; Schubert R
Eur J Pharm Sci; 2017 Oct; 108():13-22. PubMed ID: 27590127
[TBL] [Abstract][Full Text] [Related]
8. Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients.
Yamagata T; Kusuhara H; Morishita M; Takayama K; Benameur H; Sugiyama Y
Drug Metab Dispos; 2007 Jul; 35(7):1142-8. PubMed ID: 17446265
[TBL] [Abstract][Full Text] [Related]
9. A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP.
Xiao L; Yi T; Chen M; Lam CW; Zhou H
Eur J Pharm Sci; 2016 Oct; 93():456-67. PubMed ID: 27586020
[TBL] [Abstract][Full Text] [Related]
10. An animal's sex influences the effects of the excipient PEG 400 on the intestinal P-gp protein and mRNA levels, which has implications for oral drug absorption.
Mai Y; Dou L; Murdan S; Basit AW
Eur J Pharm Sci; 2018 Jul; 120():53-60. PubMed ID: 29678614
[TBL] [Abstract][Full Text] [Related]
11. Inhibitory Effects of Commonly Used Excipients on P-Glycoprotein in Vitro.
Gurjar R; Chan CYS; Curley P; Sharp J; Chiong J; Rannard S; Siccardi M; Owen A
Mol Pharm; 2018 Nov; 15(11):4835-4842. PubMed ID: 30350641
[TBL] [Abstract][Full Text] [Related]
12. Boosting drug bioavailability in men but not women through the action of an excipient.
Mai Y; Ashiru-Oredope DAI; Yao Z; Dou L; Madla CM; Taherali F; Murdan S; Basit AW
Int J Pharm; 2020 Sep; 587():119678. PubMed ID: 32710919
[TBL] [Abstract][Full Text] [Related]
13. Effects of Various Pharmaceutical Excipients on the Intestinal Transport and Absorption of Sulfasalazine, a Typical Substrate of Breast Cancer Resistance Protein Transporter.
Sawangrat K; Morishita M; Kusamori K; Katsumi H; Sakane T; Yamamoto A
J Pharm Sci; 2018 Nov; 107(11):2946-2956. PubMed ID: 30053556
[TBL] [Abstract][Full Text] [Related]
14. Interactions of Oral Molecular Excipients with Breast Cancer Resistance Protein, BCRP.
Zou L; Pottel J; Khuri N; Ngo HX; Ni Z; Tsakalozou E; Warren MS; Huang Y; Shoichet BK; Giacomini KM
Mol Pharm; 2020 Mar; 17(3):748-756. PubMed ID: 31990564
[TBL] [Abstract][Full Text] [Related]
15. A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.
Shah D; Paruchury S; Matta M; Chowan G; Subramanian M; Saxena A; Soars MG; Herbst J; Haskell R; Marathe P; Mandlekar S
Drug Metab Lett; 2014; 8(2):109-18. PubMed ID: 25429513
[TBL] [Abstract][Full Text] [Related]
16. Establishing an in vitro permeation model to predict the in vivo sex-related influence of PEG 400 on oral drug absorption.
Mai Y; Murdan S; Awadi M; Basit AW
Int J Pharm; 2018 May; 542(1-2):280-287. PubMed ID: 29530563
[TBL] [Abstract][Full Text] [Related]
17. Effect of excipients on breast cancer resistance protein substrate uptake activity.
Yamagata T; Kusuhara H; Morishita M; Takayama K; Benameur H; Sugiyama Y
J Control Release; 2007 Dec; 124(1-2):1-5. PubMed ID: 17900739
[TBL] [Abstract][Full Text] [Related]
18. Implication of metabolomics and transporter modulation based strategies to minimize multidrug resistance and enhance site-specific bioavailability: a needful consideration toward modern anticancer drug discovery.
Rachmale M; Rajput N; Jadav T; Sahu AK; Tekade RK; Sengupta P
Drug Metab Rev; 2022 May; 54(2):101-119. PubMed ID: 35254954
[TBL] [Abstract][Full Text] [Related]
19. Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology.
Andersen V; Svenningsen K; Knudsen LA; Hansen AK; Holmskov U; Stensballe A; Vogel U
World J Gastroenterol; 2015 Nov; 21(41):11862-76. PubMed ID: 26557010
[TBL] [Abstract][Full Text] [Related]
20. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice.
Marchetti S; de Vries NA; Buckle T; Bolijn MJ; van Eijndhoven MA; Beijnen JH; Mazzanti R; van Tellingen O; Schellens JH
Mol Cancer Ther; 2008 Aug; 7(8):2280-7. PubMed ID: 18723475
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]