BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 36336241)

  • 1. Chemotherapy promotes astrocytic response to Aβ deposition, but not Aβ levels, in a mouse model of amyloid and APOE.
    Ng CAS; Biran LP; Galvano E; Mandelblatt J; Vicini S; Rebeck GW
    Neurobiol Dis; 2022 Dec; 175():105915. PubMed ID: 36336241
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.
    Rodriguez GA; Tai LM; LaDu MJ; Rebeck GW
    J Neuroinflammation; 2014 Jun; 11():111. PubMed ID: 24948358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3.
    Valencia-Olvera AC; Balu D; Bellur S; McNally T; Saleh Y; Pham D; Ghura S; York J; Johansson JO; LaDu MJ; Tai L
    Alzheimers Res Ther; 2023 Dec; 15(1):216. PubMed ID: 38102668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease.
    Lin AL; Parikh I; Yanckello LM; White RS; Hartz AMS; Taylor CE; McCulloch SD; Thalman SW; Xia M; McCarty K; Ubele M; Head E; Hyder F; Sanganahalli BG
    Neurobiol Dis; 2020 Jun; 139():104834. PubMed ID: 32173556
    [TBL] [Abstract][Full Text] [Related]  

  • 5. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
    Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
    Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.
    Youmans KL; Tai LM; Nwabuisi-Heath E; Jungbauer L; Kanekiyo T; Gan M; Kim J; Eimer WA; Estus S; Rebeck GW; Weeber EJ; Bu G; Yu C; Ladu MJ
    J Biol Chem; 2012 Dec; 287(50):41774-86. PubMed ID: 23060451
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.
    Liao F; Zhang TJ; Jiang H; Lefton KB; Robinson GO; Vassar R; Sullivan PM; Holtzman DM
    Acta Neuropathol Commun; 2015 Nov; 3():70. PubMed ID: 26556230
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice.
    Xu F; Vitek MP; Colton CA; Previti ML; Gharkholonarehe N; Davis J; Van Nostrand WE
    J Neurosci; 2008 May; 28(20):5312-20. PubMed ID: 18480287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.
    Xiong M; Wang C; Gratuze M; Saadi F; Bao X; Bosch ME; Lee C; Jiang H; Serrano JR; Gonzales ER; Kipnis M; Holtzman DM
    Mol Neurodegener; 2023 Mar; 18(1):17. PubMed ID: 36922879
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice.
    Balu D; Valencia-Olvera AC; Nguyen A; Patnam M; York J; Peri F; Neumann F; LaDu MJ; Tai LM
    Alzheimers Res Ther; 2023 Oct; 15(1):181. PubMed ID: 37858252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
    Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
    Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
    Tai LM; Bilousova T; Jungbauer L; Roeske SK; Youmans KL; Yu C; Poon WW; Cornwell LB; Miller CA; Vinters HV; Van Eldik LJ; Fardo DW; Estus S; Bu G; Gylys KH; Ladu MJ
    J Biol Chem; 2013 Feb; 288(8):5914-26. PubMed ID: 23293020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice.
    Thomas R; Zuchowska P; Morris AW; Marottoli FM; Sunny S; Deaton R; Gann PH; Tai LM
    Acta Neuropathol Commun; 2016 Oct; 4(1):111. PubMed ID: 27788676
    [TBL] [Abstract][Full Text] [Related]  

  • 14. APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.
    Liu DS; Pan XD; Zhang J; Shen H; Collins NC; Cole AM; Koster KP; Ben Aissa M; Dai XM; Zhou M; Tai LM; Zhu YG; LaDu M; Chen XC
    Mol Neurodegener; 2015 Mar; 10():7. PubMed ID: 25871877
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
    Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
    J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
    Tai LM; Koster KP; Luo J; Lee SH; Wang YT; Collins NC; Ben Aissa M; Thatcher GRJ; LaDu MJ
    J Biol Chem; 2014 Oct; 289(44):30538-30555. PubMed ID: 25217640
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotype.
    Davidson Y; Gibbons L; Pritchard A; Hardicre J; Wren J; Tian J; Shi J; Stopford C; Julien C; Thompson J; Payton A; Thaker U; Hayes AJ; Iwatsubo T; Pickering-Brown SM; Pendleton N; Horan MA; Burns A; Purandare N; Lendon CL; Neary D; Snowden JS; Mann DM
    J Neurol Neurosurg Psychiatry; 2006 Apr; 77(4):515-7. PubMed ID: 16543533
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
    Pankiewicz JE; Guridi M; Kim J; Asuni AA; Sanchez S; Sullivan PM; Holtzman DM; Sadowski MJ
    Acta Neuropathol Commun; 2014 Jun; 2():75. PubMed ID: 24972680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
    Fryer JD; Simmons K; Parsadanian M; Bales KR; Paul SM; Sullivan PM; Holtzman DM
    J Neurosci; 2005 Mar; 25(11):2803-10. PubMed ID: 15772340
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.
    Hartman RE; Laurer H; Longhi L; Bales KR; Paul SM; McIntosh TK; Holtzman DM
    J Neurosci; 2002 Dec; 22(23):10083-7. PubMed ID: 12451108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.