These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 36339591)

  • 1. Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor.
    Pardon M; Claes P; Druwé S; Martini M; Siekierska A; Menet C; de Witte PAM; Copmans D
    Front Pharmacol; 2022; 13():1012622. PubMed ID: 36339591
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic ablation of hypocretin neurons alters behavioral state transitions in zebrafish.
    Elbaz I; Yelin-Bekerman L; Nicenboim J; Vatine G; Appelbaum L
    J Neurosci; 2012 Sep; 32(37):12961-72. PubMed ID: 22973020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Orexin in sleep, addiction and more: is the perfect insomnia drug at hand?
    Hoyer D; Jacobson LH
    Neuropeptides; 2013 Dec; 47(6):477-88. PubMed ID: 24215799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish.
    Prober DA; Rihel J; Onah AA; Sung RJ; Schier AF
    J Neurosci; 2006 Dec; 26(51):13400-10. PubMed ID: 17182791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypocretin/Orexin Receptor Pharmacology and Sleep Phases.
    Sun Y; Tisdale RK; Kilduff TS
    Front Neurol Neurosci; 2021; 45():22-37. PubMed ID: 34052813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Orexin OX
    Jacobson LH; Chen S; Mir S; Hoyer D
    Curr Top Behav Neurosci; 2017; 33():105-136. PubMed ID: 27909987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and development of orexin receptor antagonists as therapeutics for insomnia.
    Winrow CJ; Renger JJ
    Br J Pharmacol; 2014 Jan; 171(2):283-93. PubMed ID: 23731216
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TAK-925, an orexin 2 receptor-selective agonist, shows robust wake-promoting effects in mice.
    Yukitake H; Fujimoto T; Ishikawa T; Suzuki A; Shimizu Y; Rikimaru K; Ito M; Suzuki M; Kimura H
    Pharmacol Biochem Behav; 2019 Dec; 187():172794. PubMed ID: 31654653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Examining the role of endogenous orexins in hypothalamus-pituitary-adrenal axis endocrine function using transient dual orexin receptor antagonism in the rat.
    Steiner MA; Sciarretta C; Brisbare-Roch C; Strasser DS; Studer R; Jenck F
    Psychoneuroendocrinology; 2013 Apr; 38(4):560-71. PubMed ID: 22917622
    [TBL] [Abstract][Full Text] [Related]  

  • 10. OX2R-selective orexin agonism is sufficient to ameliorate cataplexy and sleep/wake fragmentation without inducing drug-seeking behavior in mouse model of narcolepsy.
    Yamamoto H; Nagumo Y; Ishikawa Y; Irukayama-Tomobe Y; Namekawa Y; Nemoto T; Tanaka H; Takahashi G; Tokuda A; Saitoh T; Nagase H; Funato H; Yanagisawa M
    PLoS One; 2022; 17(7):e0271901. PubMed ID: 35867683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor.
    Asada H; Im D; Hotta Y; Yasuda S; Murata T; Suno R; Iwata S
    Structure; 2022 Dec; 30(12):1582-1589.e4. PubMed ID: 36417909
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of novel orexin 2 receptor agonists with a 1,3,5‑trioxazatriquinane skeleton.
    Amezawa M; Yamamoto N; Nagumo Y; Kutsumura N; Ishikawa Y; Yanagisawa M; Nagase H; Saitoh T
    Bioorg Med Chem Lett; 2023 Feb; 82():129151. PubMed ID: 36690040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of New Orexin 2 Receptor Modulators Using
    Janockova J; Dolezal R; Nepovimova E; Kobrlova T; Benkova M; Kuca K; Konecny J; Mezeiova E; Melikova M; Hepnarova V; Ring A; Soukup O; Korabecny J
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30423961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fos expression in orexin neurons varies with behavioral state.
    Estabrooke IV; McCarthy MT; Ko E; Chou TC; Chemelli RM; Yanagisawa M; Saper CB; Scammell TE
    J Neurosci; 2001 Mar; 21(5):1656-62. PubMed ID: 11222656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Orexin receptor antagonists as therapeutic agents for insomnia.
    Equihua AC; De La Herrán-Arita AK; Drucker-Colin R
    Front Pharmacol; 2013 Dec; 4():163. PubMed ID: 24416019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
    Willie JT; Chemelli RM; Sinton CM; Tokita S; Williams SC; Kisanuki YY; Marcus JN; Lee C; Elmquist JK; Kohlmeier KA; Leonard CS; Richardson JA; Hammer RE; Yanagisawa M
    Neuron; 2003 Jun; 38(5):715-30. PubMed ID: 12797957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.
    Kantor S; Mochizuki T; Lops SN; Ko B; Clain E; Clark E; Yamamoto M; Scammell TE
    Sleep; 2013 Aug; 36(8):1129-38. PubMed ID: 23904672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.
    Irukayama-Tomobe Y; Ogawa Y; Tominaga H; Ishikawa Y; Hosokawa N; Ambai S; Kawabe Y; Uchida S; Nakajima R; Saitoh T; Kanda T; Vogt K; Sakurai T; Nagase H; Yanagisawa M
    Proc Natl Acad Sci U S A; 2017 May; 114(22):5731-5736. PubMed ID: 28507129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of Insomnia.
    Roecker AJ; Cox CD; Coleman PJ
    J Med Chem; 2016 Jan; 59(2):504-30. PubMed ID: 26317591
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers.
    Nishimura Y; Okabe S; Sasagawa S; Murakami S; Ashikawa Y; Yuge M; Kawaguchi K; Kawase R; Tanaka T
    Front Pharmacol; 2015; 6():257. PubMed ID: 26578964
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.