BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 36352508)

  • 1. Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1.
    Osório C; White JJ; Lu H; Beekhof GC; Fiocchi FR; Andriessen CA; Dijkhuizen S; Post L; Schonewille M
    Brain; 2023 Jun; 146(6):2332-2345. PubMed ID: 36352508
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN; Belozor OS; Mozhei OI; Shuvaev AN; Fritsler YV; Khilazheva ED; Mosyagina AI; Hirai H; Teschemacher AG; Kasparov S
    Cells; 2022 Jul; 11(14):. PubMed ID: 35883691
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability.
    Dell'Orco JM; Wasserman AH; Chopra R; Ingram MA; Hu YS; Singh V; Wulff H; Opal P; Orr HT; Shakkottai VG
    J Neurosci; 2015 Aug; 35(32):11292-307. PubMed ID: 26269637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Progressive impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 model mice.
    Shuvaev AN; Hosoi N; Sato Y; Yanagihara D; Hirai H
    J Physiol; 2017 Jan; 595(1):141-164. PubMed ID: 27440721
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
    Rosa JG; Hamel K; Soles A; Sheeler C; Borgenheimer E; Gilliat S; Sbrocco K; Ghanoum F; Handler HP; Forster C; Rainwater O; Cvetanovic M
    Neurobiol Dis; 2023 Mar; 178():106023. PubMed ID: 36724861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingolipid metabolism governs Purkinje cell patterned degeneration in
    Blot FGC; Krijnen WHJJ; Den Hoedt S; Osório C; White JJ; Mulder MT; Schonewille M
    Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34479994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1.
    White JJ; Bosman LWJ; Blot FGC; Osório C; Kuppens BW; Krijnen WHJJ; Andriessen C; De Zeeuw CI; Jaarsma D; Schonewille M
    Brain Pathol; 2021 Sep; 31(5):e12946. PubMed ID: 33724582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6.
    Jayabal S; Ljungberg L; Watt AJ
    J Physiol; 2017 Feb; 595(3):949-966. PubMed ID: 27531396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Memantine suppresses the excitotoxicity but fails to rescue the ataxic phenotype in SCA1 model mice.
    Belozor OS; Vasilev A; Mileiko AG; Mosina LD; Mikhailov IG; Ox DA; Boitsova EB; Shuvaev AN; Teschemacher AG; Kasparov S; Shuvaev AN
    Biomed Pharmacother; 2024 May; 174():116526. PubMed ID: 38574621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.
    Edamakanti CR; Do J; Didonna A; Martina M; Opal P
    J Clin Invest; 2018 Jun; 128(6):2252-2265. PubMed ID: 29533923
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1.
    Nanclares C; Noriega-Prieto JA; Labrada-Moncada FE; Cvetanovic M; Araque A; Kofuji P
    Neurobiol Dis; 2023 Oct; 187():106318. PubMed ID: 37802154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
    Pérez Ortiz JM; Mollema N; Toker N; Adamski CJ; O'Callaghan B; Duvick L; Friedrich J; Walters MA; Strasser J; Hawkinson JE; Zoghbi HY; Henzler C; Orr HT; Lagalwar S
    Neurobiol Dis; 2018 Aug; 116():93-105. PubMed ID: 29758256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
    Qu W; Johnson A; Kim JH; Lukowicz A; Svedberg D; Cvetanovic M
    J Neuroinflammation; 2017 May; 14(1):107. PubMed ID: 28545543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
    Asher M; Rosa JG; Rainwater O; Duvick L; Bennyworth M; Lai RY; ; Kuo SH; Cvetanovic M
    Hum Mol Genet; 2020 Jan; 29(1):117-131. PubMed ID: 31696233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1.
    Chopra R; Bushart DD; Cooper JP; Yellajoshyula D; Morrison LM; Huang H; Handler HP; Man LJ; Dansithong W; Scoles DR; Pulst SM; Orr HT; Shakkottai VG
    Hum Mol Genet; 2020 Nov; 29(19):3249-3265. PubMed ID: 32964235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Post-symptomatic Delivery of Brain-Derived Neurotrophic Factor (BDNF) Ameliorates Spinocerebellar Ataxia Type 1 (SCA1) Pathogenesis.
    Sheeler C; Rosa JG; Borgenheimer E; Mellesmoen A; Rainwater O; Cvetanovic M
    Cerebellum; 2021 Jun; 20(3):420-429. PubMed ID: 33394333
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice.
    Wozniak EAL; Chen Z; Paul S; Yang P; Figueroa KP; Friedrich J; Tschumperlin T; Berken M; Ingram M; Henzler C; Pulst SM; Orr HT
    Cell Rep; 2021 Oct; 37(2):109831. PubMed ID: 34644575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
    Kerkhof LMC; van de Warrenburg BPC; van Roon-Mom WMC; Buijsen RAM
    Biomolecules; 2023 May; 13(5):. PubMed ID: 37238658
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
    Handler HP; Duvick L; Mitchell JS; Cvetanovic M; Reighard M; Soles A; Mather KB; Rainwater O; Serres S; Nichols-Meade T; Coffin SL; You Y; Ruis BL; O'Callaghan B; Henzler C; Zoghbi HY; Orr HT
    Neuron; 2023 Feb; 111(4):493-507.e6. PubMed ID: 36577403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
    Cummings CJ; Orr HT; Zoghbi HY
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.