118 related articles for article (PubMed ID: 36368569)
1. Establishment of Neh2-Cre:tdTomato reporter mouse for monitoring the exposure history to electrophilic stress.
Kitamura H; Oishi T; Murakami S; Yamada-Kato T; Okunishi I; Yamamoto M; Katori Y; Motohashi H
Free Radic Biol Med; 2022 Nov; 193(Pt 2):610-619. PubMed ID: 36368569
[TBL] [Abstract][Full Text] [Related]
2. Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.
Smirnova NA; Haskew-Layton RE; Basso M; Hushpulian DM; Payappilly JB; Speer RE; Ahn YH; Rakhman I; Cole PA; Pinto JT; Ratan RR; Gazaryan IG
Chem Biol; 2011 Jun; 18(6):752-65. PubMed ID: 21700211
[TBL] [Abstract][Full Text] [Related]
3. Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Zhang Y; Crouch DH; Yamamoto M; Hayes JD
Biochem J; 2006 Nov; 399(3):373-85. PubMed ID: 16872277
[TBL] [Abstract][Full Text] [Related]
4. Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron.
McMahon M; Thomas N; Itoh K; Yamamoto M; Hayes JD
J Biol Chem; 2004 Jul; 279(30):31556-67. PubMed ID: 15143058
[TBL] [Abstract][Full Text] [Related]
5. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
Rojo AI; Medina-Campos ON; Rada P; Zúñiga-Toalá A; López-Gazcón A; Espada S; Pedraza-Chaverri J; Cuadrado A
Free Radic Biol Med; 2012 Jan; 52(2):473-87. PubMed ID: 22142471
[TBL] [Abstract][Full Text] [Related]
6. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
Katoh Y; Iida K; Kang MI; Kobayashi A; Mizukami M; Tong KI; McMahon M; Hayes JD; Itoh K; Yamamoto M
Arch Biochem Biophys; 2005 Jan; 433(2):342-50. PubMed ID: 15581590
[TBL] [Abstract][Full Text] [Related]
7. Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Hamada S; Shimosegawa T; Taguchi K; Nabeshima T; Yamamoto M; Masamune A
Am J Physiol Gastrointest Liver Physiol; 2018 Jan; 314(1):G65-G74. PubMed ID: 28971839
[TBL] [Abstract][Full Text] [Related]
8. Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered.
Karunatilleke NC; Fast CS; Ngo V; Brickenden A; Duennwald ML; Konermann L; Choy WY
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299054
[TBL] [Abstract][Full Text] [Related]
9. Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
Itoh K; Mimura J; Yamamoto M
Antioxid Redox Signal; 2010 Dec; 13(11):1665-78. PubMed ID: 20446768
[TBL] [Abstract][Full Text] [Related]
10. Keap1 degradation by autophagy for the maintenance of redox homeostasis.
Taguchi K; Fujikawa N; Komatsu M; Ishii T; Unno M; Akaike T; Motohashi H; Yamamoto M
Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13561-6. PubMed ID: 22872865
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.
Itoh K; Tong KI; Yamamoto M
Free Radic Biol Med; 2004 May; 36(10):1208-13. PubMed ID: 15110385
[TBL] [Abstract][Full Text] [Related]
12. Cre-loxP Reporter Mouse Reveals Stochastic Activity of the
Bittner-Eddy PD; Fischer LA; Costalonga M
Front Immunol; 2019; 10():2228. PubMed ID: 31616418
[TBL] [Abstract][Full Text] [Related]
13. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.
Eggler AL; Liu G; Pezzuto JM; van Breemen RB; Mesecar AD
Proc Natl Acad Sci U S A; 2005 Jul; 102(29):10070-5. PubMed ID: 16006525
[TBL] [Abstract][Full Text] [Related]
14. Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress.
Unoki T; Akiyama M; Kumagai Y
Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31952233
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Taguchi K; Motohashi H; Yamamoto M
Genes Cells; 2011 Feb; 16(2):123-40. PubMed ID: 21251164
[TBL] [Abstract][Full Text] [Related]
16. A New Mouse Strain with a Mutation in the NFE2L2 (NRF2) Gene.
Egorov ES; Kondratenko ND; Averina OA; Permyakov OA; Emelyanova MA; Prikhodko AS; Zinovkina LA; Sergiev PV; Zinovkin RA
Biochemistry (Mosc); 2023 Dec; 88(12):1987-1996. PubMed ID: 38462445
[TBL] [Abstract][Full Text] [Related]
17. Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.
Alam MM; Okazaki K; Nguyen LTT; Ota N; Kitamura H; Murakami S; Shima H; Igarashi K; Sekine H; Motohashi H
J Biol Chem; 2017 May; 292(18):7519-7530. PubMed ID: 28314773
[TBL] [Abstract][Full Text] [Related]
18. Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers.
Hirotsu Y; Katsuoka F; Itoh K; Yamamoto M
Genes Cells; 2011 Apr; 16(4):406-15. PubMed ID: 21392184
[TBL] [Abstract][Full Text] [Related]
19. Effect of combined exposure to environmental aliphatic electrophiles from plants on Keap1/Nrf2 activation and cytotoxicity in HepG2 cells: A model of an electrophile exposome.
Abiko Y; Aoki H; Kumagai Y
Toxicol Appl Pharmacol; 2021 Feb; 413():115392. PubMed ID: 33428920
[TBL] [Abstract][Full Text] [Related]
20. Spatial distribution of type II collagen gene expression in the mouse intervertebral disc.
Wei Y; Tower RJ; Tian Z; Mohanraj B; Mauck RL; Qin L; Zhang Y
JOR Spine; 2019 Dec; 2(4):e1070. PubMed ID: 31891119
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
