BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 36376717)

  • 1. Targeting notch signaling pathway in breast cancer stem cells through drug repurposing approach.
    Pathak Y; Camps I; Mishra A; Tripathi V
    Mol Divers; 2023 Dec; 27(6):2431-2440. PubMed ID: 36376717
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Notch Signaling in Breast Cancer: A Role in Drug Resistance.
    BeLow M; Osipo C
    Cells; 2020 Sep; 9(10):. PubMed ID: 33003540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells.
    Debeb BG; Cohen EN; Boley K; Freiter EM; Li L; Robertson FM; Reuben JM; Cristofanilli M; Buchholz TA; Woodward WA
    Breast Cancer Res Treat; 2012 Jul; 134(2):495-510. PubMed ID: 22547109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel triazole, NMK-T-057, induces autophagic cell death in breast cancer cells by inhibiting γ-secretase-mediated activation of Notch signaling.
    Das A; Narayanam MK; Paul S; Mukhnerjee P; Ghosh S; Dastidar DG; Chakrabarty S; Ganguli A; Basu B; Pal M; Chatterji U; Banerjee SK; Karmakar P; Kumar D; Chakrabarti G
    J Biol Chem; 2019 Apr; 294(17):6733-6750. PubMed ID: 30824542
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44
    Barat S; Chen X; Cuong Bui K; Bozko P; Götze J; Christgen M; Krech T; Malek NP; Plentz RR
    Stem Cells Transl Med; 2017 Mar; 6(3):819-829. PubMed ID: 28186678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance.
    Feng M; Santhanam RK; Xing H; Zhou M; Jia H
    Biochem Pharmacol; 2024 Feb; 220():115991. PubMed ID: 38135129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.
    Hsu EC; Kulp SK; Huang HL; Tu HJ; Salunke SB; Sullivan NJ; Sun D; Wicha MS; Shapiro CL; Chen CS
    Neoplasia; 2015 Jun; 17(6):497-508. PubMed ID: 26152358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by y-Secretase Inhibitor RO4929097.
    Wang L; Dai G; Yang J; Wu W; Zhang W
    Med Sci Monit; 2018 Jun; 24():4046-4053. PubMed ID: 29899322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
    Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity.
    D'Angelo RC; Ouzounova M; Davis A; Choi D; Tchuenkam SM; Kim G; Luther T; Quraishi AA; Senbabaoglu Y; Conley SJ; Clouthier SG; Hassan KA; Wicha MS; Korkaya H
    Mol Cancer Ther; 2015 Mar; 14(3):779-787. PubMed ID: 25673823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis.
    Jia H; Liu M; Wang X; Jiang Q; Wang S; Santhanam RK; Lv C; Zhao Q; Lu J
    Pharmacol Res; 2021 Jul; 169():105686. PubMed ID: 34022397
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.
    Floyd DH; Kefas B; Seleverstov O; Mykhaylyk O; Dominguez C; Comeau L; Plank C; Purow B
    Neuro Oncol; 2012 Oct; 14(10):1215-26. PubMed ID: 22962413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.
    Séveno C; Loussouarn D; Bréchet S; Campone M; Juin P; Barillé-Nion S
    Breast Cancer Res; 2012 Jun; 14(3):R96. PubMed ID: 22703841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
    Efferson CL; Winkelmann CT; Ware C; Sullivan T; Giampaoli S; Tammam J; Patel S; Mesiti G; Reilly JF; Gibson RE; Buser C; Yeatman T; Coppola D; Winter C; Clark EA; Draetta GF; Strack PR; Majumder PK
    Cancer Res; 2010 Mar; 70(6):2476-84. PubMed ID: 20197467
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radiation-induced Notch signaling in breast cancer stem cells.
    Lagadec C; Vlashi E; Alhiyari Y; Phillips TM; Bochkur Dratver M; Pajonk F
    Int J Radiat Oncol Biol Phys; 2013 Nov; 87(3):609-18. PubMed ID: 23992604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
    Schott AF; Landis MD; Dontu G; Griffith KA; Layman RM; Krop I; Paskett LA; Wong H; Dobrolecki LE; Lewis MT; Froehlich AM; Paranilam J; Hayes DF; Wicha MS; Chang JC
    Clin Cancer Res; 2013 Mar; 19(6):1512-24. PubMed ID: 23340294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia.
    Diaz-Padilla I; Wilson MK; Clarke BA; Hirte HW; Welch SA; Mackay HJ; Biagi JJ; Reedijk M; Weberpals JI; Fleming GF; Wang L; Liu G; Zhou C; Blattler C; Ivy SP; Oza AM
    Gynecol Oncol; 2015 May; 137(2):216-22. PubMed ID: 25769658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-myeloma effect of pharmacological inhibition of Notch/gamma-secretase with RO4929097 is mediated by modulation of tumor microenvironment.
    Pisklakova A; Grigson E; Ozerova M; Chen F; Sullivan DM; Nefedova Y
    Cancer Biol Ther; 2016 May; 17(5):477-85. PubMed ID: 26934342
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.
    Clementz AG; Rogowski A; Pandya K; Miele L; Osipo C
    Breast Cancer Res; 2011 Jun; 13(3):R63. PubMed ID: 21679465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of Notch signaling pathway enhanced the radiosensitivity of breast cancer cells.
    Peng JH; Wang XL; Ran L; Song JL; Zhang ZT; Liu X; Li HY
    J Cell Biochem; 2018 Nov; 119(10):8398-8409. PubMed ID: 29904942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.