These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
114 related articles for article (PubMed ID: 36382849)
1. Effect of Pevonedistat, an Investigational NEDD8-Activating Enzyme Inhibitor, on the QTc Interval in Patients With Advanced Solid Tumors. Zhou X; Richardson DL; Dowlati A; Goel S; Sahebjam S; Strauss J; Chawla S; Wang D; Mould DR; Samnotra V; Faller DV; Venkatakrishnan K; Gupta N Clin Pharmacol Drug Dev; 2023 Mar; 12(3):257-266. PubMed ID: 36382849 [TBL] [Abstract][Full Text] [Related]
2. Phase 1 Study to Evaluate the Effect of the Investigational Anticancer Agent Sapanisertib on the QTc Interval in Patients With Advanced Solid Tumors. Patel C; Goel S; Patel MR; Rangachari L; Wilbur JD; Shou Y; Venkatakrishnan K; Lockhart AC Clin Pharmacol Drug Dev; 2020 Oct; 9(7):876-888. PubMed ID: 32488989 [TBL] [Abstract][Full Text] [Related]
3. Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies. Zhou X; Nemunaitis J; Pant S; Bauer TM; Patel M; Sarantopoulos J; Craig Lockhart A; Goodman D; Huebner D; Mould DR; Venkatakrishnan K Invest New Drugs; 2018 Apr; 36(2):240-247. PubMed ID: 28819760 [TBL] [Abstract][Full Text] [Related]
4. Phase 1 study to evaluate the effects of rifampin on pharmacokinetics of pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors. Zhou X; Vaishampayan U; Mahalingam D; Harvey RD; Chung KY; Sedarati F; Dong C; Faller DV; Venkatakrishnan K; Gupta N Invest New Drugs; 2022 Oct; 40(5):1042-1050. PubMed ID: 35932388 [TBL] [Abstract][Full Text] [Related]
5. Phase I study assessing the mass balance, pharmacokinetics, and excretion of [ Zhou X; Sedarati F; Faller DV; Zhao D; Faessel HM; Chowdhury S; Bolleddula J; Li Y; Venkatakrishnan K; Papai Z Invest New Drugs; 2021 Apr; 39(2):488-498. PubMed ID: 33089874 [TBL] [Abstract][Full Text] [Related]
6. Evaluation of the Effect of Selumetinib on Cardiac Repolarization: A Randomized, Placebo- and Positive-controlled Crossover QT/QTc Study in Healthy Subjects. Zhou D; So K; Dymond AW; Vik T; Al-Huniti N; Mariani G; Zorenyi G; Huang Y; Holmes V; Severin P; Rasmussen S; Martin P Clin Ther; 2016 Dec; 38(12):2555-2566. PubMed ID: 27837934 [TBL] [Abstract][Full Text] [Related]
7. Ipragliflozin does not prolong QTc interval in healthy male and female subjects: a phase I study. Zhang W; Smulders R; Abeyratne A; Dietz A; Krauwinkel W; Kadokura T; Keirns J Clin Ther; 2013 Aug; 35(8):1150-1161.e3. PubMed ID: 23910665 [TBL] [Abstract][Full Text] [Related]
8. Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study. Hulhoven R; Rosillon D; Bridson WE; Meeus MA; Salas E; Stockis A Clin Ther; 2008 Feb; 30(2):260-70. PubMed ID: 18343264 [TBL] [Abstract][Full Text] [Related]
9. Evaluation of the Potential for QTc Prolongation With Repeated Oral Doses of Fedratinib in Patients With Advanced Solid Tumors. Ogasawara K; Xu C; Yin J; Darpo B; Carayannopoulos L; Xue H; Palmisano M; Krishna G Clin Pharmacol Drug Dev; 2021 Apr; 10(4):366-375. PubMed ID: 32673446 [TBL] [Abstract][Full Text] [Related]
10. Evaluation of the effects of bitopertin (RG1678) on cardiac repolarization: a thorough corrected QT study in healthy male volunteers. Hofmann C; Banken L; Hahn M; Swearingen D; Nagel S; Martin-Facklam M Clin Ther; 2012 Oct; 34(10):2061-71. PubMed ID: 22980315 [TBL] [Abstract][Full Text] [Related]
11. Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies. Mendzelevski B; Ferber G; Janku F; Li BT; Sullivan RJ; Welsch D; Chi W; Jackson J; Weng O; Sager PT Cancer Chemother Pharmacol; 2018 Jun; 81(6):1129-1141. PubMed ID: 29603015 [TBL] [Abstract][Full Text] [Related]
12. Talazoparib has no clinically relevant effect on QTc interval in patients with advanced solid tumors. Hoffman J; Chakrabarti J; Plotka A; Milillo Naraine A; Kanamori D; Moroose R; Nguyen L; Wang D; Wainberg ZA Anticancer Drugs; 2019 Jun; 30(5):523-532. PubMed ID: 30875341 [TBL] [Abstract][Full Text] [Related]
13. Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure-response analysis. Fudio S; Tabernero J; Subbiah V; Chawla SP; Moreno V; Longo F; Lopez R; Anton A; Trigo JM; Shapiro G; Jeong W; Villalobos VM; Lubomirov R; Fernandez-Teruel C; Alfaro V; Boni V Cancer Chemother Pharmacol; 2021 Jan; 87(1):113-124. PubMed ID: 33108504 [TBL] [Abstract][Full Text] [Related]
14. Integrated nonclinical and clinical risk assessment of the investigational proteasome inhibitor ixazomib on the QTc interval in cancer patients. Gupta N; Huh Y; Hutmacher MM; Ottinger S; Hui AM; Venkatakrishnan K Cancer Chemother Pharmacol; 2015 Sep; 76(3):507-16. PubMed ID: 26141494 [TBL] [Abstract][Full Text] [Related]
15. Thorough QT study of the effects of vildagliptin, a dipeptidyl peptidase IV inhibitor, on cardiac repolarization and conduction in healthy volunteers. He YL; Zhang Y; Serra D; Wang Y; Ligueros-Saylan M; Dole WP Curr Med Res Opin; 2011 Jul; 27(7):1453-63. PubMed ID: 21609207 [TBL] [Abstract][Full Text] [Related]
16. Effect of nalmefene 20 and 80 mg on the corrected QT interval and T-wave morphology: a randomized, double-blind, parallel-group, placebo- and moxifloxacin-controlled, single-centre study. Matz J; Graff C; Vainio PJ; Kallio A; Højer AM; Struijk JJ; Kanters JK; Andersen MP; Toft E Clin Drug Investig; 2011 Nov; 31(11):799-811. PubMed ID: 21967071 [TBL] [Abstract][Full Text] [Related]
17. Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours. Faessel H; Nemunaitis J; Bauer TM; Lockhart AC; Faller DV; Sedarati F; Zhou X; Venkatakrishnan K; Harvey RD Br J Clin Pharmacol; 2019 Jul; 85(7):1464-1473. PubMed ID: 30845347 [TBL] [Abstract][Full Text] [Related]
18. Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants. Gong X; Darpo B; Xue H; Punwani N; He K; Barbour AM; Epstein N; Landman R; Chen X; Yeleswaram S Clin Pharmacol Drug Dev; 2020 Aug; 9(6):677-688. PubMed ID: 31821750 [TBL] [Abstract][Full Text] [Related]
19. Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy. Chari A; Munder M; Weisel K; Jenner M; Bygrave C; Petrucci MT; Boccadoro M; Cavo M; van de Donk NWCJ; Turgut M; Demirkan F; Karadogan I; Libby E; Kleiman R; Kuppens S; Bandekar R; Neff T; Heuck C; Qi M; Clemens PL; Goldschmidt H Adv Ther; 2021 Feb; 38(2):1328-1341. PubMed ID: 33474705 [TBL] [Abstract][Full Text] [Related]
20. Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors. Lockhart AC; Bauer TM; Aggarwal C; Lee CB; Harvey RD; Cohen RB; Sedarati F; Nip TK; Faessel H; Dash AB; Dezube BJ; Faller DV; Dowlati A Invest New Drugs; 2019 Feb; 37(1):87-97. PubMed ID: 29781056 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]