BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 36411371)

  • 1. A20 interacts with mTORC2 to inhibit the mTORC2/Akt/Rac1 signaling axis in hepatocellular carcinoma cells.
    Wang X; Xiao Y; Dong Y; Wang Z; Yi J; Wang J; Wang X; Zhou H; Zhang L; Shi Y
    Cancer Gene Ther; 2023 Mar; 30(3):424-436. PubMed ID: 36411371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
    Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
    Chen Q; Jin J; Guo W; Tang Z; Luo Y; Ying Y; Lin H; Luo Z
    Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells.
    Venugopal SV; Caggia S; Gambrell-Sanders D; Khan SA
    Prostate; 2020 Apr; 80(5):412-423. PubMed ID: 31995655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G-Protein-Coupled Estrogen Receptor 1 Promotes Gender Disparities in Hepatocellular Carcinoma via Modulation of SIN1 and mTOR Complex 2 Activity.
    Feng G; Cai J; Huang Y; Zhu X; Gong B; Yang Z; Yan C; Hu Z; Yang L; Wang Z
    Mol Cancer Res; 2020 Dec; 18(12):1863-1875. PubMed ID: 32873626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells.
    Chen BW; Chen W; Liang H; Liu H; Liang C; Zhi X; Hu LQ; Yu XZ; Wei T; Ma T; Xue F; Zheng L; Zhao B; Feng XH; Bai XL; Liang TB
    Mol Cancer Ther; 2015 Aug; 14(8):1805-15. PubMed ID: 26026051
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
    Morrison MM; Young CD; Wang S; Sobolik T; Sanchez VM; Hicks DJ; Cook RS; Brantley-Sieders DM
    PLoS Genet; 2015 Jul; 11(7):e1005291. PubMed ID: 26132202
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Torin2 overcomes sorafenib resistance via suppressing mTORC2-AKT-BAD pathway in hepatocellular carcinoma cells.
    Hu YT; Shu ZY; Jiang JH; Xie QF; Zheng SS
    Hepatobiliary Pancreat Dis Int; 2020 Dec; 19(6):547-554. PubMed ID: 33051131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
    Gulhati P; Bowen KA; Liu J; Stevens PD; Rychahou PG; Chen M; Lee EY; Weiss HL; O'Connor KL; Gao T; Evers BM
    Cancer Res; 2011 May; 71(9):3246-56. PubMed ID: 21430067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway.
    Xu Z; Hu J; Cao H; Pilo MG; Cigliano A; Shao Z; Xu M; Ribback S; Dombrowski F; Calvisi DF; Chen X
    Exp Mol Med; 2018 Jan; 50(1):e417. PubMed ID: 29303510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A20 inhibits the motility of HCC cells induced by TNF-α.
    Wang X; Ma C; Zong Z; Xiao Y; Li N; Guo C; Zhang L; Shi Y
    Oncotarget; 2016 Mar; 7(12):14742-54. PubMed ID: 26909601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction.
    Jansson T; Castillo-Castrejon M; Gupta MB; Powell TL; Rosario FJ
    Clin Sci (Lond); 2020 Jan; 134(1):53-70. PubMed ID: 31825077
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.
    Saci A; Cantley LC; Carpenter CL
    Mol Cell; 2011 Apr; 42(1):50-61. PubMed ID: 21474067
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells.
    Zhou HC; Fang JH; Luo X; Zhang L; Yang J; Zhang C; Zhuang SM
    Oncotarget; 2014 Dec; 5(23):12177-88. PubMed ID: 25361001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reciprocal activation between MMP-8 and TGF-β1 stimulates EMT and malignant progression of hepatocellular carcinoma.
    Qin G; Luo M; Chen J; Dang Y; Chen G; Li L; Zeng J; Lu Y; Yang J
    Cancer Lett; 2016 Apr; 374(1):85-95. PubMed ID: 26872724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RhoG/Rac1 signaling pathway involved in migration and invasion of salivary adenoid cystic carcinoma cells.
    Xu ZD; Hao T; Gan YH
    Oral Dis; 2020 Mar; 26(2):302-312. PubMed ID: 31793126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G; Zhao Q; Zhang M; Fan T; Liu M; Shi X; Ren Y; Wang Y; Zhou J; Lu Z
    Biomed Pharmacother; 2018 Oct; 106():1348-1356. PubMed ID: 30119206
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling.
    Bossler F; Kuhn BJ; Günther T; Kraemer SJ; Khalkar P; Adrian S; Lohrey C; Holzer A; Shimobayashi M; Dürst M; Mayer A; Rösl F; Grundhoff A; Krijgsveld J; Hoppe-Seyler K; Hoppe-Seyler F
    mBio; 2019 Feb; 10(1):. PubMed ID: 30755508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress.
    Thompson SM; Callstrom MR; Jondal DE; Butters KA; Knudsen BE; Anderson JL; Lien KR; Sutor SL; Lee JS; Thorgeirsson SS; Grande JP; Roberts LR; Woodrum DA
    PLoS One; 2016; 11(9):e0162634. PubMed ID: 27611696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship.
    Jhanwar-Uniyal M; Wainwright JV; Mohan AL; Tobias ME; Murali R; Gandhi CD; Schmidt MH
    Adv Biol Regul; 2019 May; 72():51-62. PubMed ID: 31010692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.