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2. Molecular and behavioural abnormalities in the FUS-tg mice mimic frontotemporal lobar degeneration: Effects of old and new anti-inflammatory therapies. de Munter J; Babaevskaya D; Wolters EC; Pavlov D; Lysikova E; V Kalueff A; Gorlova A; Oplatchikova M; Pomytkin IA; Proshin A; Umriukhin A; Lesch KP; Strekalova T J Cell Mol Med; 2020 Sep; 24(17):10251-10257. PubMed ID: 32667139 [TBL] [Abstract][Full Text] [Related]
3. Neuro-Cells therapy improves motor outcomes and suppresses inflammation during experimental syndrome of amyotrophic lateral sclerosis in mice. de Munter JPJM; Shafarevich I; Liundup A; Pavlov D; Wolters EC; Gorlova A; Veniaminova E; Umriukhin A; Kalueff A; Svistunov A; Kramer BW; Lesch KP; Strekalova T CNS Neurosci Ther; 2020 May; 26(5):504-517. PubMed ID: 31867846 [TBL] [Abstract][Full Text] [Related]
4. FUS-induced neurotoxicity is prevented by inhibiting GSK-3β in a Drosophila model of amyotrophic lateral sclerosis. Choi HJ; Lee JY; Cha SJ; Han YJ; Yoon JH; Kim HJ; Kim K Hum Mol Genet; 2022 Mar; 31(6):850-862. PubMed ID: 34605896 [TBL] [Abstract][Full Text] [Related]
5. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations. Stoica R; Paillusson S; Gomez-Suaga P; Mitchell JC; Lau DH; Gray EH; Sancho RM; Vizcay-Barrena G; De Vos KJ; Shaw CE; Hanger DP; Noble W; Miller CC EMBO Rep; 2016 Sep; 17(9):1326-42. PubMed ID: 27418313 [TBL] [Abstract][Full Text] [Related]
6. Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice. Markova N; Bazhenova N; Anthony DC; Vignisse J; Svistunov A; Lesch KP; Bettendorff L; Strekalova T Prog Neuropsychopharmacol Biol Psychiatry; 2017 Apr; 75():148-156. PubMed ID: 27825907 [TBL] [Abstract][Full Text] [Related]
7. Neuroprotective effects of JGK-263 in transgenic SOD1-G93A mice of amyotrophic lateral sclerosis. Ahn SW; Jeon GS; Kim MJ; Shon JH; Kim JE; Shin JY; Kim SM; Kim SH; Ye IH; Lee KW; Hong YH; Sung JJ J Neurol Sci; 2014 May; 340(1-2):112-6. PubMed ID: 24680562 [TBL] [Abstract][Full Text] [Related]
8. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis. Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583 [TBL] [Abstract][Full Text] [Related]
9. FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy. Funikov SY; Rezvykh AP; Mazin PV; Morozov AV; Maltsev AV; Chicheva MM; Vikhareva EA; Evgen'ev MB; Ustyugov AA Neurogenetics; 2018 Aug; 19(3):189-204. PubMed ID: 29982879 [TBL] [Abstract][Full Text] [Related]
10. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725 [TBL] [Abstract][Full Text] [Related]
11. Fused in sarcoma (FUS): an oncogene goes awry in neurodegeneration. Dormann D; Haass C Mol Cell Neurosci; 2013 Sep; 56():475-86. PubMed ID: 23557964 [TBL] [Abstract][Full Text] [Related]
12. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. Qiu H; Lee S; Shang Y; Wang WY; Au KF; Kamiya S; Barmada SJ; Finkbeiner S; Lui H; Carlton CE; Tang AA; Oldham MC; Wang H; Shorter J; Filiano AJ; Roberson ED; Tourtellotte WG; Chen B; Tsai LH; Huang EJ J Clin Invest; 2014 Mar; 124(3):981-99. PubMed ID: 24509083 [TBL] [Abstract][Full Text] [Related]
13. FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations. Neumann M; Bentmann E; Dormann D; Jawaid A; DeJesus-Hernandez M; Ansorge O; Roeber S; Kretzschmar HA; Munoz DG; Kusaka H; Yokota O; Ang LC; Bilbao J; Rademakers R; Haass C; Mackenzie IR Brain; 2011 Sep; 134(Pt 9):2595-609. PubMed ID: 21856723 [TBL] [Abstract][Full Text] [Related]
14. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Korobeynikov VA; Lyashchenko AK; Blanco-Redondo B; Jafar-Nejad P; Shneider NA Nat Med; 2022 Jan; 28(1):104-116. PubMed ID: 35075293 [TBL] [Abstract][Full Text] [Related]
15. Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model. Rossaert E; Pollari E; Jaspers T; Van Helleputte L; Jarpe M; Van Damme P; De Bock K; Moisse M; Van Den Bosch L Acta Neuropathol Commun; 2019 Jul; 7(1):107. PubMed ID: 31277703 [TBL] [Abstract][Full Text] [Related]
16. Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice. Lysikova EA; Funikov S; Rezvykh AP; Chaprov KD; Kukharsky MS; Ustyugov A; Deykin AV; Flyamer IM; Boyle S; Bachurin SO; Ninkina N; Buchman VL Neurochem Res; 2020 May; 45(5):1168-1179. PubMed ID: 32157564 [TBL] [Abstract][Full Text] [Related]
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18. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging. Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605 [TBL] [Abstract][Full Text] [Related]