BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 36411655)

  • 21. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
    De Bruyn T; Ye ZW; Peeters A; Sahi J; Baes M; Augustijns PF; Annaert PP
    Eur J Pharm Sci; 2011 Jul; 43(4):297-307. PubMed ID: 21605667
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine.
    Chen C; Wu ZT; Ma LL; Ni X; Lin YF; Wang L; Chen KP; Huang CG; Pan G
    Xenobiotica; 2015; 45(12):1138-46. PubMed ID: 26068524
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
    Niu C; Wang Y; Zhao X; Tep S; Murakami E; Subramanian R; Smith B; Lai Y
    Drug Metab Dispos; 2019 Dec; 47(12):1433-1442. PubMed ID: 31582395
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.
    Bauer M; Matsuda A; Wulkersdorfer B; Philippe C; Traxl A; Özvegy-Laczka C; Stanek J; Nics L; Klebermass EM; Poschner S; Jäger W; Patik I; Bakos É; Szakács G; Wadsak W; Hacker M; Zeitlinger M; Langer O
    Clin Pharmacol Ther; 2018 Jul; 104(1):139-147. PubMed ID: 28940241
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.
    Nie Y; Yang J; Liu S; Sun R; Chen H; Long N; Jiang R; Gui C
    Xenobiotica; 2020 Mar; 50(3):297-317. PubMed ID: 31180267
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.
    Kovacsics D; Patik I; Özvegy-Laczka C
    Expert Opin Drug Metab Toxicol; 2017 Apr; 13(4):409-424. PubMed ID: 27783531
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin.
    Varma MV; Lin J; Bi YA; Rotter CJ; Fahmi OA; Lam JL; El-Kattan AF; Goosen TC; Lai Y
    Drug Metab Dispos; 2013 May; 41(5):966-74. PubMed ID: 23393219
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1.
    Higgins JW; Ke AB; Zamek-Gliszczynski MJ
    Drug Metab Dispos; 2014 Nov; 42(11):1780-4. PubMed ID: 25106415
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Liver-selective distribution in rats supports the importance of active uptake into the liver via organic anion transporting polypeptides (OATPs) in humans.
    Mikkaichi T; Nakai D; Yoshigae Y; Imaoka T; Okudaira N; Izumi T
    Drug Metab Pharmacokinet; 2015 Oct; 30(5):334-40. PubMed ID: 26403085
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes.
    Takahashi T; Uno Y; Yamazaki H; Kume T
    Biopharm Drug Dispos; 2019 Feb; 40(2):62-69. PubMed ID: 30652318
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3.
    Bednarczyk D
    Anal Biochem; 2010 Oct; 405(1):50-8. PubMed ID: 20540932
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models.
    Yoshikado T; Maeda K; Kusuhara H; Furihata KI; Sugiyama Y
    J Pharm Sci; 2017 Sep; 106(9):2739-2750. PubMed ID: 28495568
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters.
    Leuenberger M; Häusler S; Höhn V; Euler A; Stieger B; Lochner M
    J Pharmacol Exp Ther; 2021 Jun; 377(3):346-357. PubMed ID: 33782042
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mechanism-based pharmacokinetic modeling to evaluate transporter-enzyme interplay in drug interactions and pharmacogenetics of glyburide.
    Varma MV; Scialis RJ; Lin J; Bi YA; Rotter CJ; Goosen TC; Yang X
    AAPS J; 2014 Jul; 16(4):736-48. PubMed ID: 24839071
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Effect of single-dose rifampin on the pharmacokinetics of warfarin in healthy volunteers.
    Frymoyer A; Shugarts S; Browne M; Wu AH; Frassetto L; Benet LZ
    Clin Pharmacol Ther; 2010 Oct; 88(4):540-7. PubMed ID: 20703222
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium.
    Gao B; Huber RD; Wenzel A; Vavricka SR; Ismair MG; Remé C; Meier PJ
    Exp Eye Res; 2005 Jan; 80(1):61-72. PubMed ID: 15652527
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in Rats.
    Scotcher D; Melillo N; Tadimalla S; Darwich AS; Ziemian S; Ogungbenro K; Schütz G; Sourbron S; Galetin A
    Mol Pharm; 2021 Aug; 18(8):2997-3009. PubMed ID: 34283621
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
    Watanabe M; Watanabe T; Yabuki M; Tamai I
    Drug Metab Pharmacokinet; 2015 Apr; 30(2):198-204. PubMed ID: 25989893
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism.
    Sanoh S; Naritomi Y; Kitamura S; Shinagawa A; Kakuni M; Tateno C; Ohta S
    Xenobiotica; 2020 Nov; 50(11):1370-1379. PubMed ID: 32401667
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin.
    Prueksaritanont T; Chu X; Evers R; Klopfer SO; Caro L; Kothare PA; Dempsey C; Rasmussen S; Houle R; Chan G; Cai X; Valesky R; Fraser IP; Stoch SA
    Br J Clin Pharmacol; 2014 Sep; 78(3):587-98. PubMed ID: 24617605
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.