These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 36419931)

  • 1. Binding pocket stabilization by high-throughput screening of yeast display libraries.
    Lerma Romero JA; Meyners C; Christmann A; Reinbold LM; Charalampidou A; Hausch F; Kolmar H
    Front Mol Biosci; 2022; 9():1023131. PubMed ID: 36419931
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A protein engineering approach toward understanding FKBP51 conformational dynamics and mechanisms of ligand binding.
    Lerma Romero JA; Meyners C; Rupp N; Hausch F; Kolmar H
    Protein Eng Des Sel; 2023 Jan; 36():. PubMed ID: 37903068
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Accessing Transient Binding Pockets by Protein Engineering and Yeast Surface Display Screening.
    Lerma Romero JA; Kolmar H
    Methods Mol Biol; 2023; 2681():249-274. PubMed ID: 37405652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular dynamics simulation, binding free energy calculation and unbinding pathway analysis on selectivity difference between FKBP51 and FKBP52: Insight into the molecular mechanism of isoform selectivity.
    Shi D; Bai Q; Zhou S; Liu X; Liu H; Yao X
    Proteins; 2018 Jan; 86(1):43-56. PubMed ID: 29023988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
    LeMaster DM; Mustafi SM; Brecher M; Zhang J; Héroux A; Li H; Hernández G
    J Biol Chem; 2015 Jun; 290(25):15746-15757. PubMed ID: 25953903
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
    Han JT; Zhu Y; Pan DB; Xue HX; Wang S; Peng Y; Liu H; He YX; Yao X
    Comput Struct Biotechnol J; 2021; 19():4079-4091. PubMed ID: 34401048
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective Inhibitors of FKBP51 Employ Conformational Selection of Dynamic Invisible States.
    Jagtap PKA; Asami S; Sippel C; Kaila VRI; Hausch F; Sattler M
    Angew Chem Int Ed Engl; 2019 Jul; 58(28):9429-9433. PubMed ID: 31100184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. InterAKTions with FKBPs--mutational and pharmacological exploration.
    Fabian AK; März A; Neimanis S; Biondi RM; Kozany C; Hausch F
    PLoS One; 2013; 8(2):e57508. PubMed ID: 23469007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.
    Bauder M; Meyners C; Purder PL; Merz S; Sugiarto WO; Voll AM; Heymann T; Hausch F
    J Med Chem; 2021 Mar; 64(6):3320-3349. PubMed ID: 33666419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes.
    Sinars CR; Cheung-Flynn J; Rimerman RA; Scammell JG; Smith DF; Clardy J
    Proc Natl Acad Sci U S A; 2003 Feb; 100(3):868-73. PubMed ID: 12538866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Yeast Surface Display for Protein Engineering: Library Generation, Screening, and Affinity Maturation.
    Kang BH; Lax BM; Wittrup KD
    Methods Mol Biol; 2022; 2491():29-62. PubMed ID: 35482183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52.
    Mustafi SM; LeMaster DM; Hernández G
    Biochem J; 2014 Jul; 461(1):115-23. PubMed ID: 24749623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge.
    Bracher A; Kozany C; Hähle A; Wild P; Zacharias M; Hausch F
    J Mol Biol; 2013 Nov; 425(22):4134-44. PubMed ID: 23933011
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The prospect of FKBP51 as a drug target.
    Schmidt MV; Paez-Pereda M; Holsboer F; Hausch F
    ChemMedChem; 2012 Aug; 7(8):1351-9. PubMed ID: 22581765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isolation of Single-Domain Antibodies to Transmembrane Proteins Using Magnetized Yeast Cell Targets.
    Bacon K; Menegatti S; Rao BM
    Methods Mol Biol; 2022; 2446():95-119. PubMed ID: 35157270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition.
    Baughman G; Wiederrecht GJ; Campbell NF; Martin MM; Bourgeois S
    Mol Cell Biol; 1995 Aug; 15(8):4395-402. PubMed ID: 7542743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries.
    Cembrola B; Ruzza V; Troise F; Esposito ML; Sasso E; Cafaro V; Passariello M; Visconte F; Raia M; Del Vecchio L; D'Alise AM; Cortese R; Scarselli E; Zambrano N; De Lorenzo C; Nicosia A
    Biomed Res Int; 2019; 2019():6051870. PubMed ID: 31976323
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FKBP51 and FKBP12.6-Novel and tight interactors of Glomulin.
    Hähle A; Geiger TM; Merz S; Meyners C; Tianqi M; Kolos J; Hausch F
    PLoS One; 2019; 14(9):e0221926. PubMed ID: 31490997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapamycin inhibits AR signaling pathway in prostate cancer by interacting with the FK1 domain of FKBP51.
    Zhang J; Wu D; He Y; Li L; Liu S; Lu J; Gui H; Wang Y; Tao Y; Wang H; Kaushik D; Rodriguez R; Wang Z
    Biochem Biophys Rep; 2020 Sep; 23():100778. PubMed ID: 32695889
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,4-Pyrazolyl-Containing SAFit-Analogues are Selective FKBP51 Inhibitors With Improved Ligand Efficiency and Drug-Like Profile.
    Buffa V; Meyners C; Sugiarto WO; Bauder M; Gaali S; Hausch F
    ChemMedChem; 2024 May; ():e202400264. PubMed ID: 38818693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.