BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 36431769)

  • 21. RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destruction.
    Gao K; Wang C; Jin X; Xiao J; Zhang E; Yang X; Wang D; Huang H; Yu L; Zhang P
    Cancer Lett; 2016 May; 375(1):133-141. PubMed ID: 26926424
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.
    Herman AG; Hayano M; Poyurovsky MV; Shimada K; Skouta R; Prives C; Stockwell BR
    Cancer Discov; 2011 Sep; 1(4):312-25. PubMed ID: 22586610
    [TBL] [Abstract][Full Text] [Related]  

  • 23. p53 regulation: teamwork between RING domains of Mdm2 and MdmX.
    Wang X
    Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response.
    Park DE; Cheng J; Berrios C; Montero J; Cortés-Cros M; Ferretti S; Arora R; Tillgren ML; Gokhale PC; DeCaprio JA
    Proc Natl Acad Sci U S A; 2019 Jan; 116(3):1027-1032. PubMed ID: 30598450
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.
    Shloush J; Vlassov JE; Engson I; Duan S; Saridakis V; Dhe-Paganon S; Raught B; Sheng Y; Arrowsmith CH
    J Biol Chem; 2011 Feb; 286(6):4796-808. PubMed ID: 21084285
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.
    Ranaweera RS; Yang X
    J Biol Chem; 2013 Jun; 288(26):18939-46. PubMed ID: 23671280
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.
    Vogel SM; Bauer MR; Joerger AC; Wilcken R; Brandt T; Veprintsev DB; Rutherford TJ; Fersht AR; Boeckler FM
    Proc Natl Acad Sci U S A; 2012 Oct; 109(42):16906-10. PubMed ID: 23035244
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis.
    Xiong X; Zhao Y; Tang F; Wei D; Thomas D; Wang X; Liu Y; Zheng P; Sun Y
    Elife; 2014 Aug; 3():e02236. PubMed ID: 25144937
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.
    Yang H; Zheng Z; Zhao LY; Li Q; Liao D
    Cell Cycle; 2012 Feb; 11(3):582-93. PubMed ID: 22262167
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
    Xiong S; Van Pelt CS; Elizondo-Fraire AC; Liu G; Lozano G
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3226-31. PubMed ID: 16492743
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mdm2 and Mdm4 loss regulates distinct p53 activities.
    Barboza JA; Iwakuma T; Terzian T; El-Naggar AK; Lozano G
    Mol Cancer Res; 2008 Jun; 6(6):947-54. PubMed ID: 18567799
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
    Joshi Y; Sória MG; Quadrato G; Inak G; Zhou L; Hervera A; Rathore KI; Elnaggar M; Cucchiarini M; Marine JC; Puttagunta R; Di Giovanni S
    Brain; 2015 Jul; 138(Pt 7):1843-62. PubMed ID: 25981963
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.
    Štětková M; Growková K; Fojtík P; Valčíková B; Palušová V; Verlande A; Jorda R; Kryštof V; Hejret V; Alexiou P; Rotrekl V; Uldrijan S
    Cell Death Dis; 2020 Sep; 11(9):754. PubMed ID: 32934219
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans.
    Coffill CR; Lee AP; Siau JW; Chee SM; Joseph TL; Tan YS; Madhumalar A; Tay BH; Brenner S; Verma CS; Ghadessy FJ; Venkatesh B; Lane DP
    Genes Dev; 2016 Feb; 30(3):281-92. PubMed ID: 26798135
    [TBL] [Abstract][Full Text] [Related]  

  • 35. MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage.
    Di Conza G; Mancini F; Buttarelli M; Pontecorvi A; Trimarchi F; Moretti F
    Cell Cycle; 2012 Feb; 11(4):749-60. PubMed ID: 22374672
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Distinct roles of Mdm2 and Mdm4 in red cell production.
    Maetens M; Doumont G; Clercq SD; Francoz S; Froment P; Bellefroid E; Klingmuller U; Lozano G; Marine JC
    Blood; 2007 Mar; 109(6):2630-3. PubMed ID: 17105817
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.
    Grier JD; Xiong S; Elizondo-Fraire AC; Parant JM; Lozano G
    Mol Cell Biol; 2006 Jan; 26(1):192-8. PubMed ID: 16354690
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells.
    Zhang S; Yan Z; Li Y; Gong Y; Lyu X; Lou J; Zhang D; Meng X; Zhao Y
    J Med Chem; 2022 Apr; 65(8):6207-6230. PubMed ID: 35420431
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.
    Egorova O; Lau HH; McGraphery K; Sheng Y
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075226
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The expression of MDM2, MDM4, p53 and p21 in myeloid neoplasms and the effect of MDM2/MDM4 dual inhibitor.
    Eskandari M; Shi Y; Liu J; Albanese J; Goel S; Verma A; Wang Y
    Leuk Lymphoma; 2021 Jan; 62(1):167-175. PubMed ID: 32924682
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.