These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 36431829)

  • 1. Covalent Warheads Targeting Cysteine Residue: The Promising Approach in Drug Development.
    Huang F; Han X; Xiao X; Zhou J
    Molecules; 2022 Nov; 27(22):. PubMed ID: 36431829
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A road map for prioritizing warheads for cysteine targeting covalent inhibitors.
    Ábrányi-Balogh P; Petri L; Imre T; Szijj P; Scarpino A; Hrast M; Mitrović A; Fonovič UP; Németh K; Barreteau H; Roper DI; Horváti K; Ferenczy GG; Kos J; Ilaš J; Gobec S; Keserű GM
    Eur J Med Chem; 2018 Dec; 160():94-107. PubMed ID: 30321804
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterising covalent warhead reactivity.
    Martin JS; MacKenzie CJ; Fletcher D; Gilbert IH
    Bioorg Med Chem; 2019 May; 27(10):2066-2074. PubMed ID: 30975501
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The basics of thiols and cysteines in redox biology and chemistry.
    Poole LB
    Free Radic Biol Med; 2015 Mar; 80():148-57. PubMed ID: 25433365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins.
    Zeng J; Davies MJ
    Chem Res Toxicol; 2005 Aug; 18(8):1232-41. PubMed ID: 16097796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative reactivity analysis of small-molecule thiol surrogates.
    Petri L; Ábrányi-Balogh P; Varga PR; Imre T; Keserű GM
    Bioorg Med Chem; 2020 Apr; 28(7):115357. PubMed ID: 32081630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beyond cysteine: recent developments in the area of targeted covalent inhibition.
    Mukherjee H; Grimster NP
    Curr Opin Chem Biol; 2018 Jun; 44():30-38. PubMed ID: 29857316
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads.
    Karges J; Cohen SM
    J Med Chem; 2023 Feb; 66(4):3088-3105. PubMed ID: 36752718
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring the Versatility of the Covalent Thiol-Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease.
    Mons E; Kim RQ; van Doodewaerd BR; van Veelen PA; Mulder MPC; Ovaa H
    J Am Chem Soc; 2021 May; 143(17):6423-6433. PubMed ID: 33885283
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.
    Wang J; Zhou S; Cheng Y; Cheng L; Qin Y; Zhang Z; Bi A; Xiang H; He X; Tian X; Liu W; Zhang J; Peng C; Zhu Z; Huang M; Li Y; Zhuang G; Tan L
    J Med Chem; 2023 Feb; 66(4):2608-2621. PubMed ID: 36723914
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery.
    Paulsen CE; Carroll KS
    Chem Rev; 2013 Jul; 113(7):4633-79. PubMed ID: 23514336
    [No Abstract]   [Full Text] [Related]  

  • 12. Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads.
    Bálint D; Póti ÁL; Alexa A; Sok P; Albert K; Torda L; Földesi-Nagy D; Csókás D; Turczel G; Imre T; Szarka E; Fekete F; Bento I; Bojtár M; Palkó R; Szabó P; Monostory K; Pápai I; Soós T; Reményi A
    Nat Commun; 2024 Oct; 15(1):8606. PubMed ID: 39366946
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Covalent fragment approaches targeting non-cysteine residues.
    Csorba N; Ábrányi-Balogh P; Keserű GM
    Trends Pharmacol Sci; 2023 Nov; 44(11):802-816. PubMed ID: 37770315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Electrophilic warheads in covalent drug discovery: an overview.
    Péczka N; Orgován Z; Ábrányi-Balogh P; Keserű GM
    Expert Opin Drug Discov; 2022 Apr; 17(4):413-422. PubMed ID: 35129005
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thia-Michael addition: the route to promising opportunities for fast and cysteine-specific modification.
    Ahangarpour M; Kavianinia I; Brimble MA
    Org Biomol Chem; 2023 Apr; 21(15):3057-3072. PubMed ID: 36975212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A study of the reactivity of S
    Mukherjee H; Debreczeni J; Breed J; Tentarelli S; Aquila B; Dowling JE; Whitty A; Grimster NP
    Org Biomol Chem; 2017 Nov; 15(45):9685-9695. PubMed ID: 29119993
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tunable Cysteine-Targeting Electrophilic Heteroaromatic Warheads Induce Ferroptosis.
    Karaj E; Sindi SH; Kuganesan N; Perera L; Taylor W; Tillekeratne LMV
    J Med Chem; 2022 Sep; 65(17):11788-11817. PubMed ID: 35984756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.
    Müller P; Meta M; Meidner JL; Schwickert M; Meyr J; Schwickert K; Kersten C; Zimmer C; Hammerschmidt SJ; Frey A; Lahu A; de la Hoz-Rodríguez S; Agost-Beltrán L; Rodríguez S; Diemer K; Neumann W; Gonzàlez FV; Engels B; Schirmeister T
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108388
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple roles of cysteine in biocatalysis.
    Giles NM; Giles GI; Jacob C
    Biochem Biophys Res Commun; 2003 Jan; 300(1):1-4. PubMed ID: 12480511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cysteine residues as catalysts for covalent peptide and protein modification: a role for thiyl radicals?
    Schöneich C
    Biochem Soc Trans; 2011 Oct; 39(5):1254-9. PubMed ID: 21936798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.