145 related articles for article (PubMed ID: 36434903)
1. Chloroquine corrects enlarged lysosomes in FIG4 null cells and reduces neurodegeneration in Fig4 null mice.
Lenk GM; Meisler MH
Mol Genet Metab; 2022 Dec; 137(4):382-387. PubMed ID: 36434903
[TBL] [Abstract][Full Text] [Related]
2. The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants.
Cao X; Lenk GM; Mikusevic V; Mindell JA; Meisler MH
PLoS Genet; 2023 Jun; 19(6):e1010800. PubMed ID: 37363915
[TBL] [Abstract][Full Text] [Related]
3. Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes Fig4 and Pip4k2c.
Cao X; Lenk GM; Meisler MH
G3 (Bethesda); 2023 Aug; 13(8):. PubMed ID: 36691351
[TBL] [Abstract][Full Text] [Related]
4. Protective role of the lipid phosphatase Fig4 in the adult nervous system.
Mironova YA; Lin JP; Kalinski AL; Huffman LD; Lenk GM; Havton LA; Meisler MH; Giger RJ
Hum Mol Genet; 2018 Jul; 27(14):2443-2453. PubMed ID: 29688489
[TBL] [Abstract][Full Text] [Related]
5. Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase.
Campeau PM; Lenk GM; Lu JT; Bae Y; Burrage L; Turnpenny P; Román Corona-Rivera J; Morandi L; Mora M; Reutter H; Vulto-van Silfhout AT; Faivre L; Haan E; Gibbs RA; Meisler MH; Lee BH
Am J Hum Genet; 2013 May; 92(5):781-91. PubMed ID: 23623387
[TBL] [Abstract][Full Text] [Related]
6. Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene.
Lenk GM; Frei CM; Miller AC; Wallen RC; Mironova YA; Giger RJ; Meisler MH
Hum Mol Genet; 2016 Jan; 25(2):340-7. PubMed ID: 26604144
[TBL] [Abstract][Full Text] [Related]
7. FIG4 mutations leading to parkinsonism and a phenotypical continuum between CMT4J and Yunis Varón syndrome.
Zimmermann M; Schuster S; Boesch S; Korenke GC; Mohr J; Reichbauer J; Kernstock C; Kotzot D; Spahlinger V; Schüle-Freyer R; Schöls L
Parkinsonism Relat Disord; 2020 May; 74():6-11. PubMed ID: 32268254
[TBL] [Abstract][Full Text] [Related]
8. AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model.
Presa M; Bailey RM; Davis C; Murphy T; Cook J; Walls R; Wilpan H; Bogdanik L; Lenk GM; Burgess RW; Gray SJ; Lutz C
J Clin Invest; 2021 Jun; 131(11):. PubMed ID: 33878035
[TBL] [Abstract][Full Text] [Related]
9. Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient Cells.
Zou J; Hu B; Arpag S; Yan Q; Hamilton A; Zeng YS; Vanoye CG; Li J
J Neurosci; 2015 Apr; 35(17):6801-12. PubMed ID: 25926456
[TBL] [Abstract][Full Text] [Related]
10. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.
Ferguson CJ; Lenk GM; Jones JM; Grant AE; Winters JJ; Dowling JJ; Giger RJ; Meisler MH
Hum Mol Genet; 2012 Aug; 21(16):3525-34. PubMed ID: 22581779
[TBL] [Abstract][Full Text] [Related]
11. Novel FIG4 mutations in Yunis-Varon syndrome.
Nakajima J; Okamoto N; Shiraishi J; Nishimura G; Nakashima M; Tsurusaki Y; Saitsu H; Kawashima H; Matsumoto N; Miyake N
J Hum Genet; 2013 Dec; 58(12):822-4. PubMed ID: 24088667
[TBL] [Abstract][Full Text] [Related]
12. FIG4 regulates lysosome membrane homeostasis independent of phosphatase function.
Bharadwaj R; Cunningham KM; Zhang K; Lloyd TE
Hum Mol Genet; 2016 Feb; 25(4):681-92. PubMed ID: 26662798
[TBL] [Abstract][Full Text] [Related]
13. Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies.
Vaccari I; Dina G; Tronchère H; Kaufman E; Chicanne G; Cerri F; Wrabetz L; Payrastre B; Quattrini A; Weisman LS; Meisler MH; Bolino A
PLoS Genet; 2011 Oct; 7(10):e1002319. PubMed ID: 22028665
[TBL] [Abstract][Full Text] [Related]
14. Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4.
Winters JJ; Ferguson CJ; Lenk GM; Giger-Mateeva VI; Shrager P; Meisler MH; Giger RJ
J Neurosci; 2011 Nov; 31(48):17736-51. PubMed ID: 22131434
[TBL] [Abstract][Full Text] [Related]
15. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J.
Lenk GM; Ferguson CJ; Chow CY; Jin N; Jones JM; Grant AE; Zolov SN; Winters JJ; Giger RJ; Dowling JJ; Weisman LS; Meisler MH
PLoS Genet; 2011 Jun; 7(6):e1002104. PubMed ID: 21655088
[TBL] [Abstract][Full Text] [Related]
16. Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria.
Baulac S; Lenk GM; Dufresnois B; Ouled Amar Bencheikh B; Couarch P; Renard J; Larson PA; Ferguson CJ; Noé E; Poirier K; Hubans C; Ferreira S; Guerrini R; Ouazzani R; El Hachimi KH; Meisler MH; Leguern E
Neurology; 2014 Mar; 82(12):1068-75. PubMed ID: 24598713
[TBL] [Abstract][Full Text] [Related]
17. Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy.
Vaccari I; Carbone A; Previtali SC; Mironova YA; Alberizzi V; Noseda R; Rivellini C; Bianchi F; Del Carro U; D'Antonio M; Lenk GM; Wrabetz L; Giger RJ; Meisler MH; Bolino A
Hum Mol Genet; 2015 Jan; 24(2):383-96. PubMed ID: 25187576
[TBL] [Abstract][Full Text] [Related]
18. Knockdown of the Drosophila FIG4 induces deficient locomotive behavior, shortening of motor neuron, axonal targeting aberration, reduction of life span and defects in eye development.
Kyotani A; Azuma Y; Yamamoto I; Yoshida H; Mizuta I; Mizuno T; Nakagawa M; Tokuda T; Yamaguchi M
Exp Neurol; 2016 Mar; 277():86-95. PubMed ID: 26708557
[TBL] [Abstract][Full Text] [Related]
19. Fig4 deficiency: a newly emerged lysosomal storage disorder?
Martyn C; Li J
Prog Neurobiol; 2013; 101-102():35-45. PubMed ID: 23165282
[TBL] [Abstract][Full Text] [Related]
20. Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J.
Chow CY; Zhang Y; Dowling JJ; Jin N; Adamska M; Shiga K; Szigeti K; Shy ME; Li J; Zhang X; Lupski JR; Weisman LS; Meisler MH
Nature; 2007 Jul; 448(7149):68-72. PubMed ID: 17572665
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
