BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 36435355)

  • 1. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
    Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L
    Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of microtubule stabilizers with novel scaffold structures based on virtual screening, biological evaluation, and molecular dynamics simulation.
    Mao J; Luo QQ; Zhang HR; Zheng XH; Shen C; Qi HZ; Hu ML; Zhang H
    Chem Biol Interact; 2022 Jan; 352():109784. PubMed ID: 34932952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
    Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
    J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Hadizadeh F; Ghodsi R; Mirzaei S; Sahebkar A
    Comput Math Methods Med; 2022; 2022():4004068. PubMed ID: 35075369
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of novel microtubule stabilizers targeting taxane binding site by applying molecular docking, molecular dynamics simulation, and anticancer activity testing.
    Zhang H; Qi HZ; Mao J; Zhang HR; Luo QQ; Hu ML; Shen C; Ding L
    Bioorg Chem; 2022 May; 122():105722. PubMed ID: 35303622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Essential 2D and 3D Chemical Features for Discovery of the Novel Tubulin Polymerization Inhibitors.
    Azimi F; Ghasemi JB; Saghaei L; Hassanzadeh F; Mahdavi M; Sadeghi-Aliabadi H; Scotti MT; Scotti L
    Curr Top Med Chem; 2019; 19(13):1092-1120. PubMed ID: 31109275
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K; Sun Z; Zhao F; Shan G; Meng Q
    Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
    Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin.
    Sharma A; Sáez-Calvo G; Olieric N; de Asís Balaguer F; Barasoain I; Lamberth C; Díaz JF; Steinmetz MO
    Int J Mol Sci; 2017 Jun; 18(7):. PubMed ID: 28640209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U; Urbaniak A; Maj E; Moshari M; Delgado M; Wietrzyk J; Bartl F; Chambers TC; Tuszynski JA; Huczyński A
    Bioorg Chem; 2018 Dec; 81():553-566. PubMed ID: 30248507
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
    Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
    Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX; Song J; Kong LJ; Sha BB; Tian XY; Liu XJ; Hu T; Chen P; Zhang SY
    Eur J Med Chem; 2022 Feb; 229():114069. PubMed ID: 34971875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
    Guo Q; Zhang H; Deng Y; Zhai S; Jiang Z; Zhu D; Wang L
    Eur J Med Chem; 2020 Jun; 196():112328. PubMed ID: 32320841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors.
    Wang Z; Liu R; Zhang X; Chang X; Gao M; Zhang S; Guan Q; Sun J; Zuo D; Zhang W
    Bioorg Med Chem; 2022 Mar; 58():116671. PubMed ID: 35193066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations.
    Liu G; Jiao Y; Huang C; Chang P
    J Comput Aided Mol Des; 2019 Jul; 33(7):659-664. PubMed ID: 31165955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.
    Song J; Wang SH; Song CH; Zhang WX; Zhu JX; Tian XY; Fu XJ; Xu Y; Jin CY; Zhang SY
    Eur J Med Chem; 2022 Oct; 240():114583. PubMed ID: 35834904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel tubulin inhibitors targeting taxanes site by virtual screening, molecular dynamic simulation, and biological evaluation.
    Zhang H; Mao J; Yang YL; Liu CT; Shen C; Zhang HR; Xie HZ; Ding L
    J Cell Biochem; 2021 Nov; 122(11):1609-1624. PubMed ID: 34237164
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
    Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening.
    Federico LB; Silva GM; de Fraga Dias A; Figueiró F; Battastini AMO; Dos Santos CBR; Costa LT; Rosa JMC; de Paula da Silva CHT
    Int J Biol Macromol; 2020 Dec; 165(Pt B):3040-3050. PubMed ID: 33736292
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
    Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.