167 related articles for article (PubMed ID: 36439442)
1. CRISPR Cas9-mediated ablation of pyruvate carboxylase gene in colon cancer cell line HT-29 inhibits growth and migration, induces apoptosis and increases sensitivity to 5-fluorouracil and glutaminase inhibitor.
Ngamkham J; Siritutsoontorn S; Saisomboon S; Vaeteewoottacharn K; Jitrapakdee S
Front Oncol; 2022; 12():966089. PubMed ID: 36439442
[TBL] [Abstract][Full Text] [Related]
2. Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function.
Li Y; Lou W; Raja V; Denis S; Yu W; Schmidtke MW; Reynolds CA; Schlame M; Houtkooper RH; Greenberg ML
J Biol Chem; 2019 Jul; 294(30):11568-11578. PubMed ID: 31186346
[TBL] [Abstract][Full Text] [Related]
3. Overexpression of Pyruvate Carboxylase Is Correlated With Colorectal Cancer Progression and Supports Growth of Invasive Colon Cancer HT-29 Cell Line.
Ngamkham J; Thuwajit C; Thuwajit P; Khamwachirapithak P; Lertsuwan K; Charoensawan V; Jitrapakdee S
Anticancer Res; 2020 Nov; 40(11):6285-6293. PubMed ID: 33109566
[TBL] [Abstract][Full Text] [Related]
4. Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Liu C; Zhou X; Pan Y; Liu Y; Zhang Y
BMC Cancer; 2021 Jun; 21(1):722. PubMed ID: 34158007
[TBL] [Abstract][Full Text] [Related]
5. Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer.
Singleton DC; Dechaume AL; Murray PM; Katt WP; Baguley BC; Leung EY
BMC Cancer; 2020 May; 20(1):470. PubMed ID: 32450839
[TBL] [Abstract][Full Text] [Related]
6. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Cheng T; Sudderth J; Yang C; Mullen AR; Jin ES; Matés JM; DeBerardinis RJ
Proc Natl Acad Sci U S A; 2011 May; 108(21):8674-9. PubMed ID: 21555572
[TBL] [Abstract][Full Text] [Related]
7. Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Phannasil P; Ansari IH; El Azzouny M; Longacre MJ; Rattanapornsompong K; Burant CF; MacDonald MJ; Jitrapakdee S
Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):537-551. PubMed ID: 27890529
[TBL] [Abstract][Full Text] [Related]
8. Impaired G2/M cell cycle arrest induces apoptosis in pyruvate carboxylase knockdown MDA-MB-231 cells.
Rattanapornsompong K; Khattiya J; Phannasil P; Phaonakrop N; Roytrakul S; Jitrapakdee S; Akekawatchai C
Biochem Biophys Rep; 2021 Mar; 25():100903. PubMed ID: 33490650
[TBL] [Abstract][Full Text] [Related]
9. Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts.
Wang H; Lu J; Kulkarni S; Zhang W; Gorka JE; Mandel JA; Goetzman ES; Prochownik EV
J Biol Chem; 2019 Apr; 294(14):5466-5486. PubMed ID: 30755479
[TBL] [Abstract][Full Text] [Related]
10. Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.
Sellers K; Fox MP; Bousamra M; Slone SP; Higashi RM; Miller DM; Wang Y; Yan J; Yuneva MO; Deshpande R; Lane AN; Fan TW
J Clin Invest; 2015 Feb; 125(2):687-98. PubMed ID: 25607840
[TBL] [Abstract][Full Text] [Related]
11. NDRG2 inhibits pyruvate carboxylase-mediated anaplerosis and combines with glutamine blockade to inhibit the proliferation of glioma cells.
Wang J; Sun X; Wang J; Zhang K; Yuan Y; Guo Y; Yao L; Li X; Shen L
Am J Cancer Res; 2022; 12(8):3729-3744. PubMed ID: 36119843
[TBL] [Abstract][Full Text] [Related]
12. Genome-Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment.
Yang C; Lee D; Zhang MS; Tse AP; Wei L; Bao MH; Wong BP; Chan CY; Yuen VW; Chen Y; Wong CC
Adv Sci (Weinh); 2022 Dec; 9(34):e2202104. PubMed ID: 36310121
[TBL] [Abstract][Full Text] [Related]
13. 1α,25-dihydroxyvitamin D inhibits de novo fatty acid synthesis and lipid accumulation in metastatic breast cancer cells through down-regulation of pyruvate carboxylase.
Wilmanski T; Buhman K; Donkin SS; Burgess JR; Teegarden D
J Nutr Biochem; 2017 Feb; 40():194-200. PubMed ID: 27936456
[TBL] [Abstract][Full Text] [Related]
14. Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma.
Du D; Liu C; Qin M; Zhang X; Xi T; Yuan S; Hao H; Xiong J
Acta Pharm Sin B; 2022 Feb; 12(2):558-580. PubMed ID: 35256934
[TBL] [Abstract][Full Text] [Related]
15. Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells.
Phannasil P; Thuwajit C; Warnnissorn M; Wallace JC; MacDonald MJ; Jitrapakdee S
PLoS One; 2015; 10(6):e0129848. PubMed ID: 26070193
[TBL] [Abstract][Full Text] [Related]
16. Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver.
Cappel DA; Deja S; Duarte JAG; Kucejova B; Iñigo M; Fletcher JA; Fu X; Berglund ED; Liu T; Elmquist JK; Hammer S; Mishra P; Browning JD; Burgess SC
Cell Metab; 2019 Jun; 29(6):1291-1305.e8. PubMed ID: 31006591
[TBL] [Abstract][Full Text] [Related]
17. Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer.
Shinde A; Wilmanski T; Chen H; Teegarden D; Wendt MK
Breast Cancer Res; 2018 Jul; 20(1):76. PubMed ID: 30005601
[TBL] [Abstract][Full Text] [Related]
18. Long noncoding RNA OVAAL enhances nucleotide synthesis through pyruvate carboxylase to promote 5-fluorouracil resistance in gastric cancer.
Tan JN; Zhou SN; Zhang W; Yang B; Zhong GY; Huang J; Hu H; Han FH; Luo ML
Cancer Sci; 2022 Sep; 113(9):3055-3070. PubMed ID: 35657686
[TBL] [Abstract][Full Text] [Related]
19. Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling.
Shahid M; Lee MY; Piplani H; Andres AM; Zhou B; Yeon A; Kim M; Kim HL; Kim J
Cell Cycle; 2018; 17(24):2802-2818. PubMed ID: 30526248
[TBL] [Abstract][Full Text] [Related]
20. c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
Edmunds LR; Sharma L; Kang A; Lu J; Vockley J; Basu S; Uppala R; Goetzman ES; Beck ME; Scott D; Prochownik EV
J Biol Chem; 2014 Sep; 289(36):25382-92. PubMed ID: 25053415
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
