BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 36459178)

  • 1. Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.
    Tariq M; de Souza AH; Bensellam M; Chae H; Jaffredo M; Close AF; Deglasse JP; Santos LRB; Buemi A; Mourad NI; Wojtusciszyn A; Raoux M; Gilon P; Broca C; Jonas JC
    Diabetologia; 2023 Apr; 66(4):709-723. PubMed ID: 36459178
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice.
    de Souza AH; Santos LRB; Roma LP; Bensellam M; Carpinelli AR; Jonas JC
    Mol Cell Endocrinol; 2017 Jan; 439():354-362. PubMed ID: 27664519
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M; Shi YC; Chan JY; Laybutt DR; Chae H; Abou-Samra M; Pappas EG; Thomas HE; Gilon P; Jonas JC
    Diabetologia; 2019 Dec; 62(12):2273-2286. PubMed ID: 31624901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.
    Pertusa JA; Nesher R; Kaiser N; Cerasi E; Henquin JC; Jonas JC
    Diabetes; 2002 Aug; 51(8):2552-60. PubMed ID: 12145170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial oxidative stress contributes differently to rat pancreatic islet cell apoptosis and insulin secretory defects after prolonged culture in a low non-stimulating glucose concentration.
    Roma LP; Pascal SM; Duprez J; Jonas JC
    Diabetologia; 2012 Aug; 55(8):2226-37. PubMed ID: 22643931
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets.
    Sasaki N; Iwase M; Uchizono Y; Nakamura U; Imoto H; Abe S; Iida M
    Diabetologia; 2006 Dec; 49(12):2930-8. PubMed ID: 17072584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells.
    Santos LRB; Muller C; de Souza AH; Takahashi HK; Spégel P; Sweet IR; Chae H; Mulder H; Jonas JC
    Mol Metab; 2017 Jun; 6(6):535-547. PubMed ID: 28580284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration.
    Roma LP; Duprez J; Jonas JC
    Am J Physiol Endocrinol Metab; 2015 Oct; 309(7):E632-9. PubMed ID: 26264555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets.
    Björklund A; Grill V
    Diabetes; 1999 Jul; 48(7):1409-14. PubMed ID: 10389846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Paradoxical release of insulin by adult pig islets in vitro. Recovery after culture in a defined tissue culture medium.
    Davalli AM; Bertuzzi F; Socci C; Scaglia L; Gavazzi F; Freschi M; DiCarlo V; Pontiroli AE; Pozza G
    Transplantation; 1993 Jul; 56(1):148-54. PubMed ID: 7687394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of fructosamine-3-kinase deficiency on function and survival of mouse pancreatic islets after prolonged culture in high glucose or ribose concentrations.
    Pascal SM; Veiga-da-Cunha M; Gilon P; Van Schaftingen E; Jonas JC
    Am J Physiol Endocrinol Metab; 2010 Mar; 298(3):E586-96. PubMed ID: 20009024
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations.
    Duprez J; Roma LP; Close AF; Jonas JC
    PLoS One; 2012; 7(10):e46831. PubMed ID: 23056475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro.
    Sandler S; Bendtzen K; Eizirik DL; Welsh M
    Endocrinology; 1990 Feb; 126(2):1288-94. PubMed ID: 2404746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.
    Thams P; Anwar MR; Capito K
    Eur J Endocrinol; 2005 Apr; 152(4):671-7. PubMed ID: 15817925
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.
    Ritzel RA; Hansen JB; Veldhuis JD; Butler PC
    J Clin Endocrinol Metab; 2004 Feb; 89(2):795-805. PubMed ID: 14764798
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prolonged exposure of pancreatic islets isolated from "pre-diabetic" non-obese diabetic mice to a high glucose concentration does not impair beta-cell function.
    Eizirik DL; Strandell E; Sandler S
    Diabetologia; 1991 Jan; 34(1):6-11. PubMed ID: 2055343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.
    Hughes SJ; Faehling M; Thorneley CW; Proks P; Ashcroft FM; Smith PA
    Diabetes; 1998 Jan; 47(1):73-81. PubMed ID: 9421377
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fast reversibility of glucose-induced desensitization in rat pancreatic islets. Evidence for an involvement of ionic fluxes.
    Anello M; Rabuazzo AM; Degano C; Caltabiano V; Patanè G; Vigneri R; Purrello F
    Diabetes; 1996 Apr; 45(4):502-6. PubMed ID: 8603773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats.
    Medina A; Parween S; Ullsten S; Vishnu N; Siu YT; Quach M; Bennet H; Balhuizen A; Åkesson L; Wierup N; Carlsson PO; Ahlgren U; Lernmark Å; Fex M
    Diabetologia; 2018 Apr; 61(4):896-905. PubMed ID: 29209740
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells.
    Yang J; Wong RK; Park M; Wu J; Cook JR; York DA; Deng S; Markmann J; Naji A; Wolf BA; Gao Z
    Diabetes; 2006 Jan; 55(1):193-201. PubMed ID: 16380493
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.