195 related articles for article (PubMed ID: 36481721)
1. Intracellular galectin-3 is a lipopolysaccharide sensor that promotes glycolysis through mTORC1 activation.
Chen X; Yu C; Liu X; Liu B; Wu X; Wu J; Yan D; Han L; Tang Z; Yuan X; Wang J; Wang Y; Liu S; Shan L; Shang Y
Nat Commun; 2022 Dec; 13(1):7578. PubMed ID: 36481721
[TBL] [Abstract][Full Text] [Related]
2. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Shen K; Sabatini DM
Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
[TBL] [Abstract][Full Text] [Related]
3. A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.
Lawrence RE; Cho KF; Rappold R; Thrun A; Tofaute M; Kim DJ; Moldavski O; Hurley JH; Zoncu R
Nat Cell Biol; 2018 Sep; 20(9):1052-1063. PubMed ID: 30061680
[TBL] [Abstract][Full Text] [Related]
4. TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression.
Zhao L; Gao N; Peng X; Chen L; Meng T; Jiang C; Jin J; Zhang J; Duan Q; Tian H; Weng L; Wang X; Tan X; Li Y; Qin H; Yuan J; Ge X; Deng L; Wang P
Adv Sci (Weinh); 2024 Mar; 11(12):e2301164. PubMed ID: 38229144
[TBL] [Abstract][Full Text] [Related]
5. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
Nada S; Okada M
J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1.
Zhang T; Wang R; Wang Z; Wang X; Wang F; Ding J
Nat Commun; 2017 Nov; 8(1):1394. PubMed ID: 29123114
[TBL] [Abstract][Full Text] [Related]
7. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
[TBL] [Abstract][Full Text] [Related]
8. Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma.
Yao L; Xuan Y; Zhang H; Yang B; Ma X; Wang T; Meng T; Sun W; Wei H; Ma X; Moses R; Xiao J; Zhang P; Ge C; Li J; Li L; Li X; Li J; Zhang B
Oncogene; 2021 Jan; 40(3):677-692. PubMed ID: 33230243
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for the assembly of the Ragulator-Rag GTPase complex.
Yonehara R; Nada S; Nakai T; Nakai M; Kitamura A; Ogawa A; Nakatsumi H; Nakayama KI; Li S; Standley DM; Yamashita E; Nakagawa A; Okada M
Nat Commun; 2017 Nov; 8(1):1625. PubMed ID: 29158492
[TBL] [Abstract][Full Text] [Related]
10. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM
Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980
[TBL] [Abstract][Full Text] [Related]
11. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
Xu Q; Tu J; Dou C; Zhang J; Yang L; Liu X; Lei K; Liu Z; Wang Y; Li L; Bao H; Wang J; Tu K
Mol Cancer; 2017 Dec; 16(1):178. PubMed ID: 29262861
[TBL] [Abstract][Full Text] [Related]
12. Circ-PRMT5 enhances the proliferation, migration and glycolysis of hepatoma cells by targeting miR-188-5p/HK2 axis.
Ding Z; Guo L; Deng Z; Li P
Ann Hepatol; 2020; 19(3):269-279. PubMed ID: 32089501
[TBL] [Abstract][Full Text] [Related]
13. Mitochondrial GCN5L1 regulates glutaminase acetylation and hepatocellular carcinoma.
Zhang T; Cui Y; Wu Y; Meng J; Han L; Zhang J; Zhang C; Yang C; Chen L; Bai X; Zhang K; Wu K; Sack MN; Wang L; Zhu L
Clin Transl Med; 2022 May; 12(5):e852. PubMed ID: 35538890
[TBL] [Abstract][Full Text] [Related]
14. Aberrant amino acid signaling promotes growth and metastasis of hepatocellular carcinomas through Rab1A-dependent activation of mTORC1 by Rab1A.
Xu BH; Li XX; Yang Y; Zhang MY; Rao HL; Wang HY; Zheng XF
Oncotarget; 2015 Aug; 6(25):20813-28. PubMed ID: 26308575
[TBL] [Abstract][Full Text] [Related]
15. CSN5 upregulates glycolysis to promote hepatocellular carcinoma metastasis via stabilizing the HK2 protein.
Huang M; Xiong H; Luo D; Xu B; Liu H
Exp Cell Res; 2020 Mar; 388(2):111876. PubMed ID: 31991125
[TBL] [Abstract][Full Text] [Related]
16. Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Sun RF; Zhao CY; Chen S; Yu W; Zhou MM; Gao CR
Dig Dis Sci; 2021 Mar; 66(3):802-813. PubMed ID: 32274668
[TBL] [Abstract][Full Text] [Related]
17. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.
Dong P; Wang X; Liu L; Tang W; Ma L; Zeng W; Sun S; Zhang L; Zhang N; Shen X; Janssen HLA; Dong L; Zhang S; Chen S
J Hepatol; 2020 Dec; 73(6):1446-1459. PubMed ID: 32610114
[TBL] [Abstract][Full Text] [Related]
18. Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells: Role of repressing glycolysis via miR-199a:HK2/PKM2 modulation.
Li W; Qiu Y; Hao J; Zhao C; Deng X; Shu G
Food Chem Toxicol; 2018 Nov; 121():156-165. PubMed ID: 30171973
[TBL] [Abstract][Full Text] [Related]
19. Galectin-3 is associated with a poor prognosis in primary hepatocellular carcinoma.
Jiang SS; Weng DS; Wang QJ; Pan K; Zhang YJ; Li YQ; Li JJ; Zhao JJ; He J; Lv L; Pan QZ; Xia JC
J Transl Med; 2014 Sep; 12():273. PubMed ID: 25260879
[TBL] [Abstract][Full Text] [Related]
20. Persistent mTORC1 activation via Depdc5 deletion results in spontaneous hepatocellular carcinoma but does not exacerbate carcinogen- and high-fat diet-induced hepatic carcinogenesis in mice.
Xu L; Yang C; Wang J; Li Z; Huang R; Ma H; Ma J; Wang Q; Xiong X
Biochem Biophys Res Commun; 2021 Nov; 578():142-149. PubMed ID: 34562654
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
