339 related articles for article (PubMed ID: 36482422)
1. Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
Khalil B; Chhangani D; Wren MC; Smith CL; Lee JH; Li X; Puttinger C; Tsai CW; Fortin G; Morderer D; Gao J; Liu F; Lim CK; Chen J; Chou CC; Croft CL; Gleixner AM; Donnelly CJ; Golde TE; Petrucelli L; Oskarsson B; Dickson DW; Zhang K; Shorter J; Yoshimura SH; Barmada SJ; Rincon-Limas DE; Rossoll W
Mol Neurodegener; 2022 Dec; 17(1):80. PubMed ID: 36482422
[TBL] [Abstract][Full Text] [Related]
2. Mislocalization of Nup62 Contributes to TDP-43 Proteinopathy in ALS/FTLD.
Nag N; Tripathi T
ACS Chem Neurosci; 2022 Sep; 13(17):2544-2546. PubMed ID: 36001801
[TBL] [Abstract][Full Text] [Related]
3. Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD.
Khalil B; Linsenmeier M; Smith CL; Shorter J; Rossoll W
Mol Neurodegener; 2024 Jan; 19(1):8. PubMed ID: 38254150
[TBL] [Abstract][Full Text] [Related]
4. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Gleixner AM; Verdone BM; Otte CG; Anderson EN; Ramesh N; Shapiro OR; Gale JR; Mauna JC; Mann JR; Copley KE; Daley EL; Ortega JA; Cicardi ME; Kiskinis E; Kofler J; Pandey UB; Trotti D; Donnelly CJ
Nat Commun; 2022 Jun; 13(1):3380. PubMed ID: 35697676
[TBL] [Abstract][Full Text] [Related]
5. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
Chou CC; Zhang Y; Umoh ME; Vaughan SW; Lorenzini I; Liu F; Sayegh M; Donlin-Asp PG; Chen YH; Duong DM; Seyfried NT; Powers MA; Kukar T; Hales CM; Gearing M; Cairns NJ; Boylan KB; Dickson DW; Rademakers R; Zhang YJ; Petrucelli L; Sattler R; Zarnescu DC; Glass JD; Rossoll W
Nat Neurosci; 2018 Feb; 21(2):228-239. PubMed ID: 29311743
[TBL] [Abstract][Full Text] [Related]
6. Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia.
Pasetto L; Grassano M; Pozzi S; Luotti S; Sammali E; Migazzi A; Basso M; Spagnolli G; Biasini E; Micotti E; Cerovic M; Carli M; Forloni G; De Marco G; Manera U; Moglia C; Mora G; Traynor BJ; Chiò A; Calvo A; Bonetto V
Brain; 2021 Dec; 144(12):3710-3726. PubMed ID: 34972208
[TBL] [Abstract][Full Text] [Related]
7. Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology.
Anderson EN; Morera AA; Kour S; Cherry JD; Ramesh N; Gleixner A; Schwartz JC; Ebmeier C; Old W; Donnelly CJ; Cheng JP; Kline AE; Kofler J; Stein TD; Pandey UB
Elife; 2021 May; 10():. PubMed ID: 34060470
[TBL] [Abstract][Full Text] [Related]
8. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Gasset-Rosa F; Lu S; Yu H; Chen C; Melamed Z; Guo L; Shorter J; Da Cruz S; Cleveland DW
Neuron; 2019 Apr; 102(2):339-357.e7. PubMed ID: 30853299
[TBL] [Abstract][Full Text] [Related]
9. Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Khosravi B; Hartmann H; May S; Möhl C; Ederle H; Michaelsen M; Schludi MH; Dormann D; Edbauer D
Hum Mol Genet; 2017 Feb; 26(4):790-800. PubMed ID: 28040728
[TBL] [Abstract][Full Text] [Related]
10. C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD.
Ervilha Pereira P; Schuermans N; Meylemans A; LeBlanc P; Versluys L; Copley KE; Rubien JD; Altheimer C; Peetermans M; Debackere E; Vanakker O; Janssens S; Baets J; Verhoeven K; Lammens M; Symoens S; De Paepe B; Barmada SJ; Shorter J; De Bleecker JL; Bogaert E; Dermaut B
Acta Neuropathol; 2023 Jun; 145(6):793-814. PubMed ID: 37000196
[TBL] [Abstract][Full Text] [Related]
11. Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.
Nishimura AL; Zupunski V; Troakes C; Kathe C; Fratta P; Howell M; Gallo JM; Hortobágyi T; Shaw CE; Rogelj B
Brain; 2010 Jun; 133(Pt 6):1763-71. PubMed ID: 20472655
[TBL] [Abstract][Full Text] [Related]
12. Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits.
Godfrey RK; Alsop E; Bjork RT; Chauhan BS; Ruvalcaba HC; Antone J; Gittings LM; Michael AF; Williams C; Hala'ufia G; Blythe AD; Hall M; Sattler R; Van Keuren-Jensen K; Zarnescu DC
Acta Neuropathol Commun; 2023 Oct; 11(1):168. PubMed ID: 37864255
[TBL] [Abstract][Full Text] [Related]
13. Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease.
Odeh HM; Fare CM; Shorter J
J Mol Biol; 2022 Jan; 434(1):167220. PubMed ID: 34464655
[TBL] [Abstract][Full Text] [Related]
14.
Cook CN; Wu Y; Odeh HM; Gendron TF; Jansen-West K; Del Rosso G; Yue M; Jiang P; Gomes E; Tong J; Daughrity LM; Avendano NM; Castanedes-Casey M; Shao W; Oskarsson B; Tomassy GS; McCampbell A; Rigo F; Dickson DW; Shorter J; Zhang YJ; Petrucelli L
Sci Transl Med; 2020 Sep; 12(559):. PubMed ID: 32878979
[TBL] [Abstract][Full Text] [Related]
15. TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
Montalbano M; McAllen S; Cascio FL; Sengupta U; Garcia S; Bhatt N; Ellsworth A; Heidelman EA; Johnson OD; Doskocil S; Kayed R
Neurobiol Dis; 2020 Dec; 146():105130. PubMed ID: 33065281
[TBL] [Abstract][Full Text] [Related]
16. Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia.
Jovičić A; Paul JW; Gitler AD
J Neurochem; 2016 Aug; 138 Suppl 1():134-44. PubMed ID: 27087014
[TBL] [Abstract][Full Text] [Related]
17. Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration.
Zhao B; Cowan CM; Coutts JA; Christy DD; Saraph A; Hsueh SCC; Plotkin SS; Mackenzie IR; Kaplan JM; Cashman NR
Acta Neuropathol Commun; 2023 Dec; 11(1):200. PubMed ID: 38111057
[TBL] [Abstract][Full Text] [Related]
18. Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Kumar S; Phaneuf D; Cordeau P; Boutej H; Kriz J; Julien JP
Mol Neurodegener; 2021 Jan; 16(1):1. PubMed ID: 33413517
[TBL] [Abstract][Full Text] [Related]
19. Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies.
Kumar MS; Stallworth KM; Murthy AC; Lim SM; Li N; Jain A; Munro JB; Fawzi NL; Lagier-Tourenne C; Bosco DA
J Mol Biol; 2023 Mar; 435(6):167972. PubMed ID: 36690069
[TBL] [Abstract][Full Text] [Related]
20. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]