177 related articles for article (PubMed ID: 36495366)
1. Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth.
Santhana Kumar K; Brunner C; Schuster M; Kopp LL; Gries A; Yan S; Jurt S; Moehle K; Bruns D; Grotzer M; Zerbe O; Schneider G; Baumgartner M
Cell Oncol (Dordr); 2023 Apr; 46(2):331-356. PubMed ID: 36495366
[TBL] [Abstract][Full Text] [Related]
2. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.
Ong SH; Guy GR; Hadari YR; Laks S; Gotoh N; Schlessinger J; Lax I
Mol Cell Biol; 2000 Feb; 20(3):979-89. PubMed ID: 10629055
[TBL] [Abstract][Full Text] [Related]
3. Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.
Zhang K; Chu K; Wu X; Gao H; Wang J; Yuan YC; Loera S; Ho K; Wang Y; Chow W; Un F; Chu P; Yen Y
Cancer Res; 2013 Feb; 73(4):1298-307. PubMed ID: 23393200
[TBL] [Abstract][Full Text] [Related]
4. TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma.
Santhana Kumar K; Neve A; Guerreiro Stucklin AS; Kuzan-Fischer CM; Rushing EJ; Taylor MD; Tripolitsioti D; Behrmann L; Kirschenbaum D; Grotzer MA; Baumgartner M
Cell Rep; 2018 Jun; 23(13):3798-3812.e8. PubMed ID: 29949765
[TBL] [Abstract][Full Text] [Related]
5. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression.
Li Q; Alsaidan OA; Ma Y; Kim S; Liu J; Albers T; Liu K; Beharry Z; Zhao S; Wang F; Lebedyeva I; Cai H
J Biol Chem; 2018 Apr; 293(17):6434-6448. PubMed ID: 29540482
[TBL] [Abstract][Full Text] [Related]
6. EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.
Wu Y; Chen Z; Ullrich A
Biol Chem; 2003 Aug; 384(8):1215-26. PubMed ID: 12974390
[TBL] [Abstract][Full Text] [Related]
7. Fibroblast growth factor receptor 1 (FGFR1) tyrosine phosphorylation regulates binding of FGFR substrate 2alpha (FRS2alpha) but not FRS2 to the receptor.
Zhang Y; McKeehan K; Lin Y; Zhang J; Wang F
Mol Endocrinol; 2008 Jan; 22(1):167-75. PubMed ID: 17901128
[TBL] [Abstract][Full Text] [Related]
8. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
Cross MJ; Lu L; Magnusson P; Nyqvist D; Holmqvist K; Welsh M; Claesson-Welsh L
Mol Biol Cell; 2002 Aug; 13(8):2881-93. PubMed ID: 12181353
[TBL] [Abstract][Full Text] [Related]
9. Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways.
Hadari YR; Gotoh N; Kouhara H; Lax I; Schlessinger J
Proc Natl Acad Sci U S A; 2001 Jul; 98(15):8578-83. PubMed ID: 11447289
[TBL] [Abstract][Full Text] [Related]
10. FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors.
Yan KS; Kuti M; Yan S; Mujtaba S; Farooq A; Goldfarb MP; Zhou MM
J Biol Chem; 2002 May; 277(19):17088-94. PubMed ID: 11877385
[TBL] [Abstract][Full Text] [Related]
11. Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2.
Tomasovic A; Traub S; Tikkanen R
PLoS One; 2012; 7(1):e29739. PubMed ID: 22235335
[TBL] [Abstract][Full Text] [Related]
12. A novel type I fibroblast growth factor receptor activates mitogenic signaling in the absence of detectable tyrosine phosphorylation of FRS2.
Lopez ME; Korc M
J Biol Chem; 2000 May; 275(21):15933-9. PubMed ID: 10748122
[TBL] [Abstract][Full Text] [Related]
13. Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.
Manuvakhova M; Thottassery JV; Hays S; Qu Z; Rentz SS; Westbrook L; Kern FG
Oncogene; 2006 Sep; 25(44):6003-14. PubMed ID: 16682955
[TBL] [Abstract][Full Text] [Related]
14. Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis.
Dey JH; Bianchi F; Voshol J; Bonenfant D; Oakeley EJ; Hynes NE
Cancer Res; 2010 May; 70(10):4151-62. PubMed ID: 20460524
[TBL] [Abstract][Full Text] [Related]
15. Structural insights into FRS2α PTB domain recognition by neurotrophin receptor TrkB.
Zeng L; Kuti M; Mujtaba S; Zhou MM
Proteins; 2014 Jul; 82(7):1534-41. PubMed ID: 24470253
[TBL] [Abstract][Full Text] [Related]
16. The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.
Fafilek B; Balek L; Bosakova MK; Varecha M; Nita A; Gregor T; Gudernova I; Krenova J; Ghosh S; Piskacek M; Jonatova L; Cernohorsky NH; Zieba JT; Kostas M; Haugsten EM; Wesche J; Erneux C; Trantirek L; Krakow D; Krejci P
Sci Signal; 2018 Sep; 11(548):. PubMed ID: 30228226
[TBL] [Abstract][Full Text] [Related]
17. Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2.
Zhang Y; Lin Y; Bowles C; Wang F
J Biol Chem; 2004 Dec; 279(53):55348-54. PubMed ID: 15513912
[TBL] [Abstract][Full Text] [Related]
18. Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain.
Burgar HR; Burns HD; Elsden JL; Lalioti MD; Heath JK
J Biol Chem; 2002 Feb; 277(6):4018-23. PubMed ID: 11729184
[TBL] [Abstract][Full Text] [Related]
19. Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins.
Gotoh N
Cancer Sci; 2008 Jul; 99(7):1319-25. PubMed ID: 18452557
[TBL] [Abstract][Full Text] [Related]
20. The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.
Agazie YM; Movilla N; Ischenko I; Hayman MJ
Oncogene; 2003 Oct; 22(44):6909-18. PubMed ID: 14534538
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]