151 related articles for article (PubMed ID: 36511302)
1. The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer.
Sfakianos AP; Raven RM; Willis AE
Biochem Soc Trans; 2022 Dec; 50(6):1885-1895. PubMed ID: 36511302
[TBL] [Abstract][Full Text] [Related]
2. Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment.
Park MH; Kar RK; Banka S; Ziegler A; Chung WK
Amino Acids; 2022 Apr; 54(4):485-499. PubMed ID: 34273022
[TBL] [Abstract][Full Text] [Related]
3. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
[TBL] [Abstract][Full Text] [Related]
4. Bi-allelic variants in DOHH, catalyzing the last step of hypusine biosynthesis, are associated with a neurodevelopmental disorder.
Ziegler A; Steindl K; Hanner AS; Kar RK; Prouteau C; Boland A; Deleuze JF; Coubes C; Bézieau S; Küry S; Maystadt I; Le Mao M; Lenaers G; Navet B; Faivre L; Tran Mau-Them F; Zanoni P; Chung WK; Rauch A; Bonneau D; Park MH
Am J Hum Genet; 2022 Aug; 109(8):1549-1558. PubMed ID: 35858628
[TBL] [Abstract][Full Text] [Related]
5. Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder.
Ganapathi M; Padgett LR; Yamada K; Devinsky O; Willaert R; Person R; Au PB; Tagoe J; McDonald M; Karlowicz D; Wolf B; Lee J; Shen Y; Okur V; Deng L; LeDuc CA; Wang J; Hanner A; Mirmira RG; Park MH; Mastracci TL; Chung WK
Am J Hum Genet; 2019 Feb; 104(2):287-298. PubMed ID: 30661771
[TBL] [Abstract][Full Text] [Related]
6. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Coni S; Serrao SM; Yurtsever ZN; Di Magno L; Bordone R; Bertani C; Licursi V; Ianniello Z; Infante P; Moretti M; Petroni M; Guerrieri F; Fatica A; Macone A; De Smaele E; Di Marcotullio L; Giannini G; Maroder M; Agostinelli E; Canettieri G
Cell Death Dis; 2020 Dec; 11(12):1045. PubMed ID: 33303756
[TBL] [Abstract][Full Text] [Related]
7. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation.
Park MH; Wolff EC
J Biol Chem; 2018 Nov; 293(48):18710-18718. PubMed ID: 30257869
[TBL] [Abstract][Full Text] [Related]
8. Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression.
Zhou J; Pang J; Tripathi M; Ho JP; Widjaja AA; Shekeran SG; Cook SA; Suzuki A; Diehl AM; Petretto E; Singh BK; Yen PM
Nat Commun; 2022 Sep; 13(1):5202. PubMed ID: 36057633
[TBL] [Abstract][Full Text] [Related]
9. Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
Kar RK; Hanner AS; Starost MF; Springer D; Mastracci TL; Mirmira RG; Park MH
J Biol Chem; 2021 Nov; 297(5):101333. PubMed ID: 34688659
[TBL] [Abstract][Full Text] [Related]
10. Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A.
Kang KR; Kim YS; Wolff EC; Park MH
J Biol Chem; 2007 Mar; 282(11):8300-8. PubMed ID: 17213197
[TBL] [Abstract][Full Text] [Related]
11. Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.
Padgett LR; Shinkle MR; Rosario S; Stewart TM; Foley JR; Casero RA; Park MH; Chung WK; Mastracci TL
HGG Adv; 2023 Jul; 4(3):100206. PubMed ID: 37333770
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes.
Martella M; Catalanotto C; Talora C; La Teana A; Londei P; Benelli D
Int J Mol Sci; 2020 Jun; 21(13):. PubMed ID: 32605139
[TBL] [Abstract][Full Text] [Related]
13. A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer.
Fujimura K; Wright T; Strnadel J; Kaushal S; Metildi C; Lowy AM; Bouvet M; Kelber JA; Klemke RL
Cancer Res; 2014 Nov; 74(22):6671-81. PubMed ID: 25261239
[TBL] [Abstract][Full Text] [Related]
14. Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence.
Martinez-Rocha AL; Woriedh M; Chemnitz J; Willingmann P; Kröger C; Hadeler B; Hauber J; Schäfer W
Sci Rep; 2016 Apr; 6():24698. PubMed ID: 27098988
[TBL] [Abstract][Full Text] [Related]
15. Hypusination-induced DHPS/eIF5A pathway as a new therapeutic strategy for human diseases: A mechanistic review and structural classification of DHPS inhibitors.
Guo JS; Liu KL; Qin YX; Hou L; Jian LY; Yang YH; Li XY
Biomed Pharmacother; 2023 Nov; 167():115440. PubMed ID: 37683595
[TBL] [Abstract][Full Text] [Related]
16. Hypusination, a Metabolic Posttranslational Modification of eIF5A in Plants during Development and Environmental Stress Responses.
Pálfi P; Bakacsy L; Kovács H; Szepesi Á
Plants (Basel); 2021 Jun; 10(7):. PubMed ID: 34206171
[TBL] [Abstract][Full Text] [Related]
17. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
Wolff EC; Kang KR; Kim YS; Park MH
Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
[TBL] [Abstract][Full Text] [Related]
18. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
Park MH
J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
[TBL] [Abstract][Full Text] [Related]
19. The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.
Patel PH; Costa-Mattioli M; Schulze KL; Bellen HJ
J Cell Biol; 2009 Jun; 185(7):1181-94. PubMed ID: 19546244
[TBL] [Abstract][Full Text] [Related]
20. Translation Factor eIF5A, Modification with Hypusine and Role in Regulation of Gene Expression. eIF5A as a Target for Pharmacological Interventions.
Turpaev KT
Biochemistry (Mosc); 2018 Aug; 83(8):863-873. PubMed ID: 30208826
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]