BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 36522488)

  • 1. The CMG helicase and cancer: a tumor "engine" and weakness with missing mutations.
    Xiang S; Reed DR; Alexandrow MG
    Oncogene; 2023 Feb; 42(7):473-490. PubMed ID: 36522488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer: Myc Over-Activation of CMG Helicases Drives Tumorigenesis and Creates a Vulnerability in CMGs for Therapeutic Intervention.
    Reed DR; Alexandrow MG
    Bioessays; 2020 Apr; 42(4):e1900218. PubMed ID: 32080866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Sulfolobus solfataricus GINS Complex Stimulates DNA Binding and Processive DNA Unwinding by Minichromosome Maintenance Helicase.
    Lang S; Huang L
    J Bacteriol; 2015 Nov; 197(21):3409-20. PubMed ID: 26283767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin.
    Xu X; Wang JT; Li M; Liu Y
    J Biol Chem; 2016 Oct; 291(43):22544-22558. PubMed ID: 27587400
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unwinding Helicase MCM Functionality for Diagnosis and Therapeutics of Replication Abnormalities Associated with Cancer: A Review.
    Radhakrishnan A; Gangopadhyay R; Sharma C; Kapardar RK; Sharma NK; Srivastav R
    Mol Diagn Ther; 2024 May; 28(3):249-264. PubMed ID: 38530633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CryoEM structures of human CMG-ATPγS-DNA and CMG-AND-1 complexes.
    Rzechorzek NJ; Hardwick SW; Jatikusumo VA; Chirgadze DY; Pellegrini L
    Nucleic Acids Res; 2020 Jul; 48(12):6980-6995. PubMed ID: 32453425
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DONSON is required for CMG helicase assembly in the mammalian cell cycle.
    Evrin C; Alvarez V; Ainsworth J; Fujisawa R; Alabert C; Labib KP
    EMBO Rep; 2023 Nov; 24(11):e57677. PubMed ID: 37781960
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Site-specific MCM sumoylation prevents genome rearrangements by controlling origin-bound MCM.
    Quan Y; Zhang QY; Zhou AL; Wang Y; Cai J; Gao YQ; Zhou H
    PLoS Genet; 2022 Jun; 18(6):e1010275. PubMed ID: 35696436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mcm10 plays a role in functioning of the eukaryotic replicative DNA helicase, Cdc45-Mcm-GINS.
    Watase G; Takisawa H; Kanemaki MT
    Curr Biol; 2012 Feb; 22(4):343-9. PubMed ID: 22285032
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeast.
    Akman G; MacNeill SA
    BMC Cell Biol; 2009 Feb; 10():12. PubMed ID: 19228417
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The structural mechanism of dimeric DONSON in replicative helicase activation.
    Cvetkovic MA; Passaretti P; Butryn A; Reynolds-Winczura A; Kingsley G; Skagia A; Fernandez-Cuesta C; Poovathumkadavil D; George R; Chauhan AS; Jhujh SS; Stewart GS; Gambus A; Costa A
    Mol Cell; 2023 Nov; 83(22):4017-4031.e9. PubMed ID: 37820732
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimizing CMG helicase and CMG-dependent replication assays by designing DNA fork substrates and choosing nucleotide analogues for helicase preloading.
    Yao NY; O'Donnell ME
    Methods Enzymol; 2022; 672():173-202. PubMed ID: 35934475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
    Baretić D; Jenkyn-Bedford M; Aria V; Cannone G; Skehel M; Yeeles JTP
    Mol Cell; 2020 Jun; 78(5):926-940.e13. PubMed ID: 32369734
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure and evolutionary origins of the CMG complex.
    Onesti S; MacNeill SA
    Chromosoma; 2013 Mar; 122(1-2):47-53. PubMed ID: 23412083
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disorders in the CMG helicase complex increase the proliferative capacity and delay chronological aging of budding yeast.
    Stępień K; Skoneczna A; Kula-Maximenko M; Jurczyk Ł; Mołoń M
    Biochim Biophys Acta Mol Cell Res; 2024 Jan; 1871(1):119621. PubMed ID: 37907194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel role of DONSON in CMG helicase assembly during vertebrate DNA replication initiation.
    Hashimoto Y; Sadano K; Miyata N; Ito H; Tanaka H
    EMBO J; 2023 Sep; 42(17):e114131. PubMed ID: 37458194
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DDK promotes DNA replication initiation: Mechanistic and structural insights.
    Li N; Gao N; Zhai Y
    Curr Opin Struct Biol; 2023 Feb; 78():102504. PubMed ID: 36525878
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
    Xiang S; Luo X; Welch D; Reed DR; Alexandrow MG
    Res Sq; 2023 Aug; ():. PubMed ID: 37609279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mcm10 coordinates the timely assembly and activation of the replication fork helicase.
    Perez-Arnaiz P; Bruck I; Kaplan DL
    Nucleic Acids Res; 2016 Jan; 44(1):315-29. PubMed ID: 26582917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes.
    Polasek-Sedlackova H; Miller TCR; Krejci J; Rask MB; Lukas J
    Nat Commun; 2022 Oct; 13(1):6090. PubMed ID: 36241664
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.