228 related articles for article (PubMed ID: 36527420)
1. MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Kim HC; Zhang Y; King PH; Lu L
J Neurochem; 2023 Mar; 164(5):643-657. PubMed ID: 36527420
[TBL] [Abstract][Full Text] [Related]
2. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S; Jeon YM; Cha SJ; Kim S; Kwon Y; Jo M; Jang YN; Lee S; Kim J; Kim SR; Lee KJ; Lee SB; Kim K; Kim HJ
Autophagy; 2020 Aug; 16(8):1396-1412. PubMed ID: 31690171
[TBL] [Abstract][Full Text] [Related]
3. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z; Lim J; Wang Q; Purtell K; Wu S; Palomo GM; Tan H; Manfredi G; Zhao Y; Peng J; Hu B; Chen S; Yue Z
Autophagy; 2020 May; 16(5):917-931. PubMed ID: 31362587
[TBL] [Abstract][Full Text] [Related]
4. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
5. Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis.
Freischmidt A; Müller K; Ludolph AC; Weishaupt JH
Acta Neuropathol Commun; 2013 Jul; 1():42. PubMed ID: 24252274
[TBL] [Abstract][Full Text] [Related]
6. The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
Yamashita T; Kwak S
Brain Res; 2014 Oct; 1584():28-38. PubMed ID: 24355598
[TBL] [Abstract][Full Text] [Related]
7. Evidence of A Negative Feedback Network Between TDP-43 and miRNAs Dependent on TDP-43 Nuclear Localization.
Hawley ZCE; Campos-Melo D; Strong MJ
J Mol Biol; 2020 Dec; 432(24):166695. PubMed ID: 33137311
[TBL] [Abstract][Full Text] [Related]
8. TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.
Maekawa S; Leigh PN; King A; Jones E; Steele JC; Bodi I; Shaw CE; Hortobagyi T; Al-Sarraj S
Neuropathology; 2009 Dec; 29(6):672-83. PubMed ID: 19496940
[TBL] [Abstract][Full Text] [Related]
9. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
[TBL] [Abstract][Full Text] [Related]
10. Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43).
Shodai A; Morimura T; Ido A; Uchida T; Ayaki T; Takahashi R; Kitazawa S; Suzuki S; Shirouzu M; Kigawa T; Muto Y; Yokoyama S; Takahashi R; Kitahara R; Ito H; Fujiwara N; Urushitani M
J Biol Chem; 2013 May; 288(21):14886-905. PubMed ID: 23558684
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA Metabolism and Dysregulation in Amyotrophic Lateral Sclerosis.
Rinchetti P; Rizzuti M; Faravelli I; Corti S
Mol Neurobiol; 2018 Mar; 55(3):2617-2630. PubMed ID: 28421535
[TBL] [Abstract][Full Text] [Related]
12. Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene.
Shimizu H; Toyoshima Y; Shiga A; Yokoseki A; Arakawa K; Sekine Y; Shimohata T; Ikeuchi T; Nishizawa M; Kakita A; Onodera O; Takahashi H
Acta Neuropathol; 2013 Sep; 126(3):453-9. PubMed ID: 23812289
[TBL] [Abstract][Full Text] [Related]
13. ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation.
Foster AD; Downing P; Figredo E; Polain N; Stott A; Layfield R; Rea SL
Mol Cell Neurosci; 2020 Oct; 108():103539. PubMed ID: 32835772
[TBL] [Abstract][Full Text] [Related]
14. Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology.
Teyssou E; Takeda T; Lebon V; Boillée S; Doukouré B; Bataillon G; Sazdovitch V; Cazeneuve C; Meininger V; LeGuern E; Salachas F; Seilhean D; Millecamps S
Acta Neuropathol; 2013 Apr; 125(4):511-22. PubMed ID: 23417734
[TBL] [Abstract][Full Text] [Related]
15. Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).
Volkening K; Leystra-Lantz C; Yang W; Jaffee H; Strong MJ
Brain Res; 2009 Dec; 1305():168-82. PubMed ID: 19815002
[TBL] [Abstract][Full Text] [Related]
16. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord.
Braak H; Ludolph A; Thal DR; Del Tredici K
Acta Neuropathol; 2010 Jul; 120(1):67-74. PubMed ID: 20379728
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.
Cykowski MD; Powell SZ; Appel JW; Arumanayagam AS; Rivera AL; Appel SH
Acta Neuropathol Commun; 2018 Apr; 6(1):28. PubMed ID: 29653597
[TBL] [Abstract][Full Text] [Related]
18. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1
Mitsui S; Otomo A; Nozaki M; Ono S; Sato K; Shirakawa R; Adachi H; Aoki M; Sobue G; Shang HF; Hadano S
Mol Brain; 2018 May; 11(1):30. PubMed ID: 29843805
[TBL] [Abstract][Full Text] [Related]
19. The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway.
Ciura S; Sellier C; Campanari ML; Charlet-Berguerand N; Kabashi E
Autophagy; 2016 Aug; 12(8):1406-8. PubMed ID: 27245636
[TBL] [Abstract][Full Text] [Related]
20. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
