BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 36535551)

  • 1. Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
    Brendza R; Gao X; Stark KL; Lin H; Lee SH; Hu C; Cai H; DiCara D; Hsiao YC; Ngu H; Foreman O; Baca M; Dohse M; Fortin JP; Corpuz R; Seshasayee D; Easton A; Ayalon G; Hötzel I; Chih B
    Neurobiol Dis; 2023 Feb; 177():105969. PubMed ID: 36535551
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.
    Parmasad JA; Ricke KM; Nguyen B; Stykel MG; Buchner-Duby B; Bruce A; Geertsma HM; Lian E; Lengacher NA; Callaghan SM; Joselin A; Tomlinson JJ; Schlossmacher MG; Stanford WL; Ma J; Brundin P; Ryan SD; Rousseaux MWC
    Cell Death Dis; 2024 Apr; 15(4):246. PubMed ID: 38575601
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-7 Protects Against Neurodegeneration Induced by α-Synuclein Preformed Fibrils in the Mouse Brain.
    Zhang J; Zhao M; Yan R; Liu J; Maddila S; Junn E; Mouradian MM
    Neurotherapeutics; 2021 Oct; 18(4):2529-2540. PubMed ID: 34697773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthetic Peucedanocoumarin IV Prevents α-Synuclein Neurotoxicity in an Animal Model of Parkinson's Disease.
    Kim H; Maeng HJ; Kim JH; Yoon JH; Oh Y; Paek SM; Lee Y
    Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
    Mao X; Ou MT; Karuppagounder SS; Kam TI; Yin X; Xiong Y; Ge P; Umanah GE; Brahmachari S; Shin JH; Kang HC; Zhang J; Xu J; Chen R; Park H; Andrabi SA; Kang SU; Gonçalves RA; Liang Y; Zhang S; Qi C; Lam S; Keiler JA; Tyson J; Kim D; Panicker N; Yun SP; Workman CJ; Vignali DA; Dawson VL; Ko HS; Dawson TM
    Science; 2016 Sep; 353(6307):. PubMed ID: 27708076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
    Patterson JR; Duffy MF; Kemp CJ; Howe JW; Collier TJ; Stoll AC; Miller KM; Patel P; Levine N; Moore DJ; Luk KC; Fleming SM; Kanaan NM; Paumier KL; El-Agnaf OMA; Sortwell CE
    Neurobiol Dis; 2019 Oct; 130():104525. PubMed ID: 31276792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
    Yang ZX; Zhang Y; Wang Q; Zhang L; Liu YF; Zhang Y; Ren Y; Zhou C; Gao HW; Zhang NX; Feng LY
    Acta Pharmacol Sin; 2024 Jan; 45(1):36-51. PubMed ID: 37684382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.
    Cosden M; Jinn S; Yao L; Gretzula CA; Kandebo M; Toolan D; Hatcher NG; Ma L; Lemaire W; Adam GC; Burlein C; Minnick C; Flick R; Watt ML; Mulhearn J; Fraley M; Drolet RE; Marcus JN; Smith SM
    Neurobiol Dis; 2021 Nov; 159():105507. PubMed ID: 34509608
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo.
    Wu Q; Shaikh MA; Meymand ES; Zhang B; Luk KC; Trojanowski JQ; Lee VM
    Acta Neuropathol; 2020 Dec; 140(6):831-849. PubMed ID: 33021680
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protective mechanisms by glial cell line-derived neurotrophic factor and cerebral dopamine neurotrophic factor against the α-synuclein accumulation in Parkinson's disease.
    Er S; Airavaara M
    Biochem Soc Trans; 2023 Feb; 51(1):245-257. PubMed ID: 36794783
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein.
    Merghani MM; Ardah MT; Al Shamsi M; Kitada T; Haque ME
    Neurotoxicology; 2021 May; 84():41-52. PubMed ID: 33549656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacological inhibition of AIMP2 aggregation attenuates α-synuclein aggregation and toxicity in Parkinson's disease.
    Shin JY; Lee B; Ham S; Kim JH; Kim H; Kim H; Jo MG; Kim HJ; Park SW; Kweon HS; Kim YJ; Yun SP; Lee Y
    Biomed Pharmacother; 2022 Dec; 156():113908. PubMed ID: 36283223
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy.
    Vermilyea SC; Christensen A; Meints J; Singh B; Martell-Martínez H; Karim MR; Lee MK
    Transl Neurodegener; 2022 Jul; 11(1):34. PubMed ID: 35773715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
    Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
    Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD8 T cell nigral infiltration precedes synucleinopathy in early stages of Parkinson's disease.
    Galiano-Landeira J; Torra A; Vila M; Bové J
    Brain; 2020 Dec; 143(12):3717-3733. PubMed ID: 33118032
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Spreading and Effects of Human Recombinant α-Synuclein Preformed Fibrils in the Cerebrospinal Fluid of Mice.
    Vandendriessche C; Bruggeman A; Foroozandeh J; Van Hoecke L; Dujardin P; Xie J; Van Imschoot G; Van Wonterghem E; Castelein J; Lucci C; De Groef L; Vandenbroucke RE
    eNeuro; 2024 Mar; 11(3):. PubMed ID: 38383588
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease.
    Sossi V; Patterson JR; McCormick S; Kemp CJ; Miller KM; Stoll AC; Kuhn N; Kubik M; Kochmanski J; Luk KC; Sortwell CE
    Mov Disord; 2022 Aug; 37(8):1739-1748. PubMed ID: 35524682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The MHC class II transactivator modulates seeded alpha-synuclein pathology and dopaminergic neurodegeneration in an in vivo rat model of Parkinson's disease.
    Jimenez-Ferrer I; Bäckström F; Dueñas-Rey A; Jewett M; Boza-Serrano A; Luk KC; Deierborg T; Swanberg M
    Brain Behav Immun; 2021 Jan; 91():369-382. PubMed ID: 33223048
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein.
    Howe JW; Sortwell CE; Duffy MF; Kemp CJ; Russell CP; Kubik M; Patel P; Luk KC; El-Agnaf OMA; Patterson JR
    Parkinsonism Relat Disord; 2021 Aug; 89():41-47. PubMed ID: 34218047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nur77 increases mitophagy and decreases aggregation of α-synuclein by modulating the p-c-Abl/p-PHB2 Y121 in α-synuclein PFF SH-SY5Y cells and mice.
    Yin S; Shen M; Zhang Y; Wu J; Song R; Lai X; Tian Z; Wang T; Jin W; Yan J
    Eur J Med Chem; 2024 Mar; 268():116251. PubMed ID: 38422699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.