BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 36536137)

  • 1. Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer.
    Liu J; Zhang C; Zhang T; Chang CY; Wang J; Bazile L; Zhang L; Haffty BG; Hu W; Feng Z
    Nat Metab; 2022 Dec; 4(12):1830-1846. PubMed ID: 36536137
    [TBL] [Abstract][Full Text] [Related]  

  • 2. miR-30a-5p suppresses breast tumor growth and metastasis through inhibition of LDHA-mediated Warburg effect.
    Li L; Kang L; Zhao W; Feng Y; Liu W; Wang T; Mai H; Huang J; Chen S; Liang Y; Han J; Xu X; Ye Q
    Cancer Lett; 2017 Aug; 400():89-98. PubMed ID: 28461244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis.
    Jin L; Chun J; Pan C; Alesi GN; Li D; Magliocca KR; Kang Y; Chen ZG; Shin DM; Khuri FR; Fan J; Kang S
    Oncogene; 2017 Jul; 36(27):3797-3806. PubMed ID: 28218905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy.
    Feng Y; Xiong Y; Qiao T; Li X; Jia L; Han Y
    Cancer Med; 2018 Dec; 7(12):6124-6136. PubMed ID: 30403008
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression.
    Chang CC; Zhang C; Zhang Q; Sahin O; Wang H; Xu J; Xiao Y; Zhang J; Rehman SK; Li P; Hung MC; Behbod F; Yu D
    Oncotarget; 2016 Jun; 7(23):35270-83. PubMed ID: 27150057
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells.
    Rong Y; Wu W; Ni X; Kuang T; Jin D; Wang D; Lou W
    Tumour Biol; 2013 Jun; 34(3):1523-30. PubMed ID: 23404405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
    Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
    J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression.
    Cui J; Shi M; Xie D; Wei D; Jia Z; Zheng S; Gao Y; Huang S; Xie K
    Clin Cancer Res; 2014 May; 20(10):2595-606. PubMed ID: 24634381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer.
    Shi M; Cui J; Du J; Wei D; Jia Z; Zhang J; Zhu Z; Gao Y; Xie K
    Clin Cancer Res; 2014 Aug; 20(16):4370-80. PubMed ID: 24947925
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FOXM1-LDHA signaling promoted gastric cancer glycolytic phenotype and progression.
    Jiang W; Zhou F; Li N; Li Q; Wang L
    Int J Clin Exp Pathol; 2015; 8(6):6756-63. PubMed ID: 26261559
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival.
    Mack N; Mazzio EA; Bauer D; Flores-Rozas H; Soliman KF
    Anticancer Res; 2017 Mar; 37(3):1205-1212. PubMed ID: 28314283
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer.
    Wang J; Wang H; Liu A; Fang C; Hao J; Wang Z
    Oncotarget; 2015 Aug; 6(23):19456-68. PubMed ID: 26062441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lactate dehydrogenase A silencing in IDH mutant gliomas.
    Chesnelong C; Chaumeil MM; Blough MD; Al-Najjar M; Stechishin OD; Chan JA; Pieper RO; Ronen SM; Weiss S; Luchman HA; Cairncross JG
    Neuro Oncol; 2014 May; 16(5):686-95. PubMed ID: 24366912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MiR-33b inhibits osteosarcoma cell proliferation through suppression of glycolysis by targeting Lactate Dehydrogenase A (LDHA).
    Zheng XM; Xu CW; Wang F
    Cell Mol Biol (Noisy-le-grand); 2018 Aug; 64(11):31-35. PubMed ID: 30213286
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of LDH in tumor glycolysis: Regulation of LDHA by small molecules for cancer therapeutics.
    Sharma D; Singh M; Rani R
    Semin Cancer Biol; 2022 Dec; 87():184-195. PubMed ID: 36371026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma.
    Li J; Zhu S; Tong J; Hao H; Yang J; Liu Z; Wang Y
    Neuroreport; 2016 Jan; 27(2):110-5. PubMed ID: 26694942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression.
    Su Y; Yu QH; Wang XY; Yu LP; Wang ZF; Cao YC; Li JD
    BMC Cancer; 2017 Jul; 17(1):477. PubMed ID: 28693517
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.
    Judge JL; Owens KM; Pollock SJ; Woeller CF; Thatcher TH; Williams JP; Phipps RP; Sime PJ; Kottmann RM
    Am J Physiol Lung Cell Mol Physiol; 2015 Oct; 309(8):L879-87. PubMed ID: 26254422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.
    Le A; Cooper CR; Gouw AM; Dinavahi R; Maitra A; Deck LM; Royer RE; Vander Jagt DL; Semenza GL; Dang CV
    Proc Natl Acad Sci U S A; 2010 Feb; 107(5):2037-42. PubMed ID: 20133848
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The lactate dehydrogenase (LDH) isoenzyme spectrum enables optimally controlling T cell glycolysis and differentiation.
    Chen X; Liu L; Kang S; Gnanaprakasam JR; Wang R
    Sci Adv; 2023 Mar; 9(12):eadd9554. PubMed ID: 36961904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.