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4. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. Shaikh LH; Zhou J; Teo AE; Garg S; Neogi SG; Figg N; Yeo GS; Yu H; Maguire JJ; Zhao W; Bennett MR; Azizan EA; Davenport AP; McKenzie G; Brown MJ J Clin Endocrinol Metab; 2015 Jun; 100(6):E836-44. PubMed ID: 25915569 [TBL] [Abstract][Full Text] [Related]
5. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. van Andel H; Ren Z; Koopmans I; Joosten SP; Kocemba KA; de Lau W; Kersten MJ; de Bruin AM; Guikema JE; Clevers H; Spaargaren M; Pals ST Proc Natl Acad Sci U S A; 2017 Jan; 114(2):376-381. PubMed ID: 28028233 [TBL] [Abstract][Full Text] [Related]
6. LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway. Zhu C; Zheng XF; Yang YH; Li B; Wang YR; Jiang SD; Jiang LS Cell Signal; 2016 Aug; 28(8):989-1000. PubMed ID: 27140682 [TBL] [Abstract][Full Text] [Related]
7. Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis. Han XH; Jin YR; Tan L; Kosciuk T; Lee JS; Yoon JK Mol Cell Biol; 2014 Feb; 34(4):752-64. PubMed ID: 24344199 [TBL] [Abstract][Full Text] [Related]
8. Lgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/β-catenin pathway. Yang YY; Zhou YM; Xu JZ; Sun LH; Tao B; Wang WQ; Wang JQ; Zhao HY; Liu JM J Bone Miner Res; 2021 Aug; 36(8):1605-1620. PubMed ID: 33950533 [TBL] [Abstract][Full Text] [Related]
9. LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells. Yue Z; Yuan Z; Zeng L; Wang Y; Lai L; Li J; Sun P; Xue X; Qi J; Yang Z; Zheng Y; Fang Y; Li D; Siwko S; Li Y; Luo J; Liu M FASEB J; 2018 May; 32(5):2422-2437. PubMed ID: 29269400 [TBL] [Abstract][Full Text] [Related]
10. Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways. Xu P; Dang Y; Wang L; Liu X; Ren X; Gu J; Liu M; Dai X; Ye X Cancer Lett; 2016 Dec; 383(2):161-170. PubMed ID: 27693558 [TBL] [Abstract][Full Text] [Related]
11. R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5. Ruffner H; Sprunger J; Charlat O; Leighton-Davies J; Grosshans B; Salathe A; Zietzling S; Beck V; Therier M; Isken A; Xie Y; Zhang Y; Hao H; Shi X; Liu D; Song Q; Clay I; Hintzen G; Tchorz J; Bouchez LC; Michaud G; Finan P; Myer VE; Bouwmeester T; Porter J; Hild M; Bassilana F; Parker CN; Cong F PLoS One; 2012; 7(7):e40976. PubMed ID: 22815884 [TBL] [Abstract][Full Text] [Related]
12. Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis. Qian Y; Liu S; Guan Y; Pan H; Guan X; Qiu Z; Li L; Gao N; Zhao Y; Li X; Lu Y; Liu M; Li D Development; 2013 Apr; 140(8):1751-61. PubMed ID: 23533175 [TBL] [Abstract][Full Text] [Related]
13. Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases. Park S; Wu L; Tu J; Yu W; Toh Y; Carmon KS; Liu QJ Sci Signal; 2020 Dec; 13(660):. PubMed ID: 33262293 [No Abstract] [Full Text] [Related]
14. Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice. Liu S; Qian Y; Li L; Wei G; Guan Y; Pan H; Guan X; Zhang L; Lu X; Zhao Y; Liu M; Li D J Biol Chem; 2013 Mar; 288(13):8794-803; discussion 8804. PubMed ID: 23393138 [TBL] [Abstract][Full Text] [Related]
15. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Carmon KS; Gong X; Yi J; Thomas A; Liu Q Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1221-9. PubMed ID: 24639526 [TBL] [Abstract][Full Text] [Related]
16. R-spondin 2-LGR4 system regulates growth, migration and invasion, epithelial-mesenchymal transition and stem-like properties of tongue squamous cell carcinoma via Wnt/β-catenin signaling. Zhang L; Song Y; Ling Z; Li Y; Ren X; Yang J; Wang Z; Xia J; Zhang W; Cheng B EBioMedicine; 2019 Jun; 44():275-288. PubMed ID: 31097406 [TBL] [Abstract][Full Text] [Related]
17. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling. Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411 [TBL] [Abstract][Full Text] [Related]
18. Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway. Pan H; Cui H; Liu S; Qian Y; Wu H; Li L; Guan Y; Guan X; Zhang L; Fan HY; Ma Y; Li R; Liu M; Li D Endocrinology; 2014 Sep; 155(9):3624-37. PubMed ID: 24877628 [TBL] [Abstract][Full Text] [Related]
20. The Role of LGR4 (GPR48) in Normal and Cancer Processes. Ordaz-Ramos A; Rosales-Gallegos VH; Melendez-Zajgla J; Maldonado V; Vazquez-Santillan K Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946652 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]