These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 36541070)

  • 1. WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures.
    Mengoli V; Ceppi I; Sanchez A; Cannavo E; Halder S; Scaglione S; Gaillard PH; McHugh PJ; Riesen N; Pettazzoni P; Cejka P
    EMBO J; 2023 Feb; 42(3):e111998. PubMed ID: 36541070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WRN Is a Promising Synthetic Lethal Target for Cancers with Microsatellite Instability (MSI).
    Chan EM; Foster KJ; Bass AJ
    Cancer Treat Res; 2023; 186():313-328. PubMed ID: 37978143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors.
    Saydam N; Kanagaraj R; Dietschy T; Garcia PL; Peña-Diaz J; Shevelev I; Stagljar I; Janscak P
    Nucleic Acids Res; 2007; 35(17):5706-16. PubMed ID: 17715146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells.
    Lieb S; Blaha-Ostermann S; Kamper E; Rippka J; Schwarz C; Ehrenhöfer-Wölfer K; Schlattl A; Wernitznig A; Lipp JJ; Nagasaka K; van der Lelij P; Bader G; Koi M; Goel A; Neumüller RA; Peters JM; Kraut N; Pearson MA; Petronczki M; Wöhrle S
    Elife; 2019 Mar; 8():. PubMed ID: 30910006
    [TBL] [Abstract][Full Text] [Related]  

  • 5. WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
    Chan EM; Shibue T; McFarland JM; Gaeta B; Ghandi M; Dumont N; Gonzalez A; McPartlan JS; Li T; Zhang Y; Bin Liu J; Lazaro JB; Gu P; Piett CG; Apffel A; Ali SO; Deasy R; Keskula P; Ng RWS; Roberts EA; Reznichenko E; Leung L; Alimova M; Schenone M; Islam M; Maruvka YE; Liu Y; Roper J; Raghavan S; Giannakis M; Tseng YY; Nagel ZD; D'Andrea A; Root DE; Boehm JS; Getz G; Chang S; Golub TR; Tsherniak A; Vazquez F; Bass AJ
    Nature; 2019 Apr; 568(7753):551-556. PubMed ID: 30971823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts.
    Zecevic A; Menard H; Gurel V; Hagan E; DeCaro R; Zhitkovich A
    Cell Cycle; 2009 Sep; 8(17):2769-78. PubMed ID: 19652551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
    van Wietmarschen N; Sridharan S; Nathan WJ; Tubbs A; Chan EM; Callen E; Wu W; Belinky F; Tripathi V; Wong N; Foster K; Noorbakhsh J; Garimella K; Cruz-Migoni A; Sommers JA; Huang Y; Borah AA; Smith JT; Kalfon J; Kesten N; Fugger K; Walker RL; Dolzhenko E; Eberle MA; Hayward BE; Usdin K; Freudenreich CH; Brosh RM; West SC; McHugh PJ; Meltzer PS; Bass AJ; Nussenzweig A
    Nature; 2020 Oct; 586(7828):292-298. PubMed ID: 32999459
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair.
    DuPrie ML; Palacio T; Calil FA; Kolodner RD; Putnam CD
    DNA Repair (Amst); 2022 Nov; 119():103405. PubMed ID: 36122480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Immunohistochemical Analysis of Mismatch Repair Gene Proteins in Early Gastric Cancer Based on Microsatellite Status.
    Sugimoto R; Endo M; Osakabe M; Toya Y; Yanagawa N; Matsumoto T; Sugai T
    Digestion; 2021; 102(5):691-700. PubMed ID: 33053554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relationship between MLH1, PMS2, MSH2 and MSH6 gene-specific alterations and tumor mutational burden in 1057 microsatellite instability-high solid tumors.
    Salem ME; Bodor JN; Puccini A; Xiu J; Goldberg RM; Grothey A; Korn WM; Shields AF; Worrilow WM; Kim ES; Lenz HJ; Marshall JL; Hall MJ
    Int J Cancer; 2020 Nov; 147(10):2948-2956. PubMed ID: 32449172
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Analysis of microsatellite instability in endometroid carcinoma with deficient mismatch repair].
    Zhang YH; Wu HW; Wang J; Liang ZY
    Zhonghua Bing Li Xue Za Zhi; 2021 May; 50(5):470-475. PubMed ID: 33915653
    [No Abstract]   [Full Text] [Related]  

  • 12. Mismatch Repair Protein Expression and Microsatellite Instability in Cutaneous Squamous Cell Carcinoma.
    Gambichler T; Ganjuur N; Tannapfel A; Vogt M; Scholl L; Abu Rached N; Bruckmüller S; Skrygan M; Becker JC; Käfferlein HU; Brüning T; Lang K
    Curr Oncol; 2021 Aug; 28(5):3316-3322. PubMed ID: 34590599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.
    Picco G; Cattaneo CM; van Vliet EJ; Crisafulli G; Rospo G; Consonni S; Vieira SF; Rodríguez IS; Cancelliere C; Banerjee R; Schipper LJ; Oddo D; Dijkstra KK; Cinatl J; Michaelis M; Yang F; Di Nicolantonio F; Sartore-Bianchi A; Siena S; Arena S; Voest EE; Bardelli A; Garnett MJ;
    Cancer Discov; 2021 Aug; 11(8):1923-1937. PubMed ID: 33837064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Germline mismatch repair gene variants analyzed by universal sequencing in Japanese cancer patients.
    Kiyozumi Y; Matsubayashi H; Horiuchi Y; Higashigawa S; Oishi T; Abe M; Ohnami S; Urakami K; Nagashima T; Kusuhara M; Miyake H; Yamaguchi K
    Cancer Med; 2019 Sep; 8(12):5534-5543. PubMed ID: 31386297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mismatch repair pathway: molecules, functions, and role in colorectal carcinogenesis.
    Sameer AS; Nissar S; Fatima K
    Eur J Cancer Prev; 2014 Jul; 23(4):246-57. PubMed ID: 24614649
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome.
    Tamura K; Kaneda M; Futagawa M; Takeshita M; Kim S; Nakama M; Kawashita N; Tatsumi-Miyajima J
    Int J Clin Oncol; 2019 Sep; 24(9):999-1011. PubMed ID: 31273487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High homogeneity of mismatch repair deficiency in advanced prostate cancer.
    Fraune C; Simon R; Höflmayer D; Möller K; Dum D; Büscheck F; Hube-Magg C; Makrypidi-Fraune G; Kluth M; Hinsch A; Burandt E; Clauditz TS; Wilczak W; Sauter G; Steurer S
    Virchows Arch; 2020 May; 476(5):745-752. PubMed ID: 31811435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Mismatch repair protein expression of colorectal cancer: a retrospective analysis of 3 428 cases].
    Liu Y; Guo YH; Luo Y; Sun L; Zhao S; Shao B; Zang FL; Qiu ZQ; Sun BC; Sun Y
    Zhonghua Bing Li Xue Za Zhi; 2021 Apr; 50(4):369-375. PubMed ID: 33831997
    [No Abstract]   [Full Text] [Related]  

  • 19. Microsatellite instability: an update.
    Yamamoto H; Imai K
    Arch Toxicol; 2015 Jun; 89(6):899-921. PubMed ID: 25701956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability.
    Yang H; Kang M; Jang S; Baek SY; Kim J; Kim GU; Kim D; Ha J; Kim JS; Jung C; Kim NJ; Cho SY; Shin WH; Lee J; Ko J; Lee A; Keum G; Lee S; Kang T
    Bioorg Med Chem; 2024 Feb; 100():117588. PubMed ID: 38295487
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.