342 related articles for article (PubMed ID: 36555634)
1. The Mammalian Cysteine Protease Legumain in Health and Disease.
Solberg R; Lunde NN; Forbord KM; Okla M; Kassem M; Jafari A
Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555634
[TBL] [Abstract][Full Text] [Related]
2. Mammalian legumain - A lysosomal cysteine protease with extracellular functions?
Lunde NN; Bosnjak T; Solberg R; Johansen HT
Biochimie; 2019 Nov; 166():77-83. PubMed ID: 31181234
[TBL] [Abstract][Full Text] [Related]
3. Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain.
Sexton KB; Witte MD; Blum G; Bogyo M
Bioorg Med Chem Lett; 2007 Feb; 17(3):649-53. PubMed ID: 17189693
[TBL] [Abstract][Full Text] [Related]
4. Recent advances in the development of legumain-selective chemical probes and peptide prodrugs.
Poreba M
Biol Chem; 2019 Nov; 400(12):1529-1550. PubMed ID: 31021817
[TBL] [Abstract][Full Text] [Related]
5. Pharmacological inhibition of asparaginyl endopeptidase by δ-secretase inhibitor 11 mitigates Alzheimer's disease-related pathologies in a senescence-accelerated mouse model.
Wang J; Hu HJ; Liu ZK; Liu JJ; Wang SS; Cheng Q; Chen HZ; Song M
Transl Neurodegener; 2021 Mar; 10(1):12. PubMed ID: 33789744
[TBL] [Abstract][Full Text] [Related]
6. Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase.
Chen JM; Dando PM; Rawlings ND; Brown MA; Young NE; Stevens RA; Hewitt E; Watts C; Barrett AJ
J Biol Chem; 1997 Mar; 272(12):8090-8. PubMed ID: 9065484
[TBL] [Abstract][Full Text] [Related]
7. Structure and function of legumain in health and disease.
Dall E; Brandstetter H
Biochimie; 2016 Mar; 122():126-50. PubMed ID: 26403494
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain.
Lee J; Bogyo M
Bioorg Med Chem Lett; 2012 Feb; 22(3):1340-3. PubMed ID: 22243962
[TBL] [Abstract][Full Text] [Related]
9. Intra- and extracellular regulation of activity and processing of legumain by cystatin E/M.
Smith R; Johansen HT; Nilsen H; Haugen MH; Pettersen SJ; Mælandsmo GM; Abrahamson M; Solberg R
Biochimie; 2012 Dec; 94(12):2590-9. PubMed ID: 22902879
[TBL] [Abstract][Full Text] [Related]
10. High expression of the cysteine proteinase legumain in colorectal cancer - implications for therapeutic targeting.
Haugen MH; Boye K; Nesland JM; Pettersen SJ; Egeland EV; Tamhane T; Brix K; Maelandsmo GM; Flatmark K
Eur J Cancer; 2015 Jan; 51(1):9-17. PubMed ID: 25466510
[TBL] [Abstract][Full Text] [Related]
11. Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions.
Lunde NN; Haugen MH; Bodin Larsen KB; Damgaard I; Pettersen SJ; Kasem R; Rut W; Drag M; Poreba M; Johansen HT; Solberg R
Biochimie; 2017 Aug; 139():27-37. PubMed ID: 28528272
[TBL] [Abstract][Full Text] [Related]
12. The Cysteine Protease Legumain Is Upregulated by Vitamin D and Is a Regulator of Vitamin D Metabolism in Mice.
Forbord KM; Okla M; Lunde NN; Bosnjak-Olsen T; Arnekleiv G; Hesselson D; Johansen HT; Tang JCY; Kassem M; Solberg R; Jafari A
Cells; 2023 Dec; 13(1):. PubMed ID: 38201240
[TBL] [Abstract][Full Text] [Related]
13. Lansoprazole inhibits the cysteine protease legumain by binding to the active site.
Bosnjak T; Solberg R; Hemati PD; Jafari A; Kassem M; Johansen HT
Basic Clin Pharmacol Toxicol; 2019 Aug; 125(2):89-99. PubMed ID: 30916878
[TBL] [Abstract][Full Text] [Related]
14. Legumain/asparaginyl endopeptidase controls extracellular matrix remodeling through the degradation of fibronectin in mouse renal proximal tubular cells.
Morita Y; Araki H; Sugimoto T; Takeuchi K; Yamane T; Maeda T; Yamamoto Y; Nishi K; Asano M; Shirahama-Noda K; Nishimura M; Uzu T; Hara-Nishimura I; Koya D; Kashiwagi A; Ohkubo I
FEBS Lett; 2007 Apr; 581(7):1417-24. PubMed ID: 17350006
[TBL] [Abstract][Full Text] [Related]
15. Structural and functional studies of legumain-mycocypin complexes revealed a competitive, exosite-regulated mode of interaction.
Elamin T; Santos NP; Briza P; Brandstetter H; Dall E
J Biol Chem; 2022 Oct; 298(10):102502. PubMed ID: 36116553
[TBL] [Abstract][Full Text] [Related]
16. The Asparaginyl Endopeptidase Legumain: An Emerging Therapeutic Target and Potential Biomarker for Alzheimer's Disease.
Song M
Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142134
[TBL] [Abstract][Full Text] [Related]
17. Legumain Functions as a Transient TrkB Sheddase.
Holzner C; Böttinger K; Blöchl C; Huber CG; Dahms SO; Dall E; Brandstetter H
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982466
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity.
Smith RL; Åstrand OA; Nguyen LM; Elvestrand T; Hagelin G; Solberg R; Johansen HT; Rongved P
Bioorg Med Chem; 2014 Jul; 22(13):3309-15. PubMed ID: 24842619
[TBL] [Abstract][Full Text] [Related]
19. Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.
Brix K; McInnes J; Al-Hashimi A; Rehders M; Tamhane T; Haugen MH
Protoplasma; 2015 May; 252(3):755-74. PubMed ID: 25398648
[TBL] [Abstract][Full Text] [Related]
20. Pig kidney legumain: an asparaginyl endopeptidase with restricted specificity.
Dando PM; Fortunato M; Smith L; Knight CG; McKendrick JE; Barrett AJ
Biochem J; 1999 May; 339 ( Pt 3)(Pt 3):743-9. PubMed ID: 10215615
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]