229 related articles for article (PubMed ID: 36571978)
1. Aggregated alpha-synuclein transcriptionally activates pro-inflammatory canonical and non-canonical NF-κB signaling pathways in peripheral monocytic cells.
Bearoff F; Dhavale D; Kotzbauer P; Kortagere S
Mol Immunol; 2023 Feb; 154():1-10. PubMed ID: 36571978
[TBL] [Abstract][Full Text] [Related]
2. Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson's Disease.
Li Y; Xia Y; Yin S; Wan F; Hu J; Kou L; Sun Y; Wu J; Zhou Q; Huang J; Xiong N; Wang T
Front Immunol; 2021; 12():719807. PubMed ID: 34691027
[TBL] [Abstract][Full Text] [Related]
3. Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo.
Dutta D; Jana M; Majumder M; Mondal S; Roy A; Pahan K
Nat Commun; 2021 Sep; 12(1):5382. PubMed ID: 34508096
[TBL] [Abstract][Full Text] [Related]
4. Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease.
Rocha SM; Kirkley KS; Chatterjee D; Aboellail TA; Smeyne RJ; Tjalkens RB
Glia; 2023 Sep; 71(9):2154-2179. PubMed ID: 37199240
[TBL] [Abstract][Full Text] [Related]
5. Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity.
Stoll AC; Sortwell CE
Neurobiol Dis; 2022 Sep; 171():105804. PubMed ID: 35764290
[TBL] [Abstract][Full Text] [Related]
6. The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia.
Cao S; Standaert DG; Harms AS
J Neuroinflammation; 2012 Nov; 9():259. PubMed ID: 23186369
[TBL] [Abstract][Full Text] [Related]
7. Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein.
Merghani MM; Ardah MT; Al Shamsi M; Kitada T; Haque ME
Neurotoxicology; 2021 May; 84():41-52. PubMed ID: 33549656
[TBL] [Abstract][Full Text] [Related]
8. [Electroacupuncture improves behavioral activities by suppressing neuroinflammation and TLR4/NF-κB signaling in substantia nigra of midbrain in Parkinson's disease rats].
Qi L; Wang Y; Li YN; Guo L; Ma J
Zhen Ci Yan Jiu; 2021 Nov; 46(11):929-34. PubMed ID: 34865329
[TBL] [Abstract][Full Text] [Related]
9. α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Ca
Leandrou E; Chalatsa I; Anagnostou D; Machalia C; Semitekolou M; Filippa V; Makridakis M; Vlahou A; Anastasiadou E; Vekrellis K; Emmanouilidou E
Transl Neurodegener; 2024 Feb; 13(1):11. PubMed ID: 38378800
[TBL] [Abstract][Full Text] [Related]
10. Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.
López de Maturana R; Lang V; Zubiarrain A; Sousa A; Vázquez N; Gorostidi A; Águila J; López de Munain A; Rodríguez M; Sánchez-Pernaute R
J Neuroinflammation; 2016 Nov; 13(1):295. PubMed ID: 27863501
[TBL] [Abstract][Full Text] [Related]
11. Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.
Williams GP; Schonhoff AM; Jurkuvenaite A; Thome AD; Standaert DG; Harms AS
J Neuroinflammation; 2018 Aug; 15(1):244. PubMed ID: 30165873
[TBL] [Abstract][Full Text] [Related]
12. NF-κB/NLRP3 inflammasome axis and risk of Parkinson's disease in Type 2 diabetes mellitus: A narrative review and new perspective.
Alrouji M; Al-Kuraishy HM; Al-Gareeb AI; Alexiou A; Papadakis M; Jabir MS; Saad HM; Batiha GE
J Cell Mol Med; 2023 Jul; 27(13):1775-1789. PubMed ID: 37210624
[TBL] [Abstract][Full Text] [Related]
13. α-synuclein promotes neuroprotection through NF-κB-mediated transcriptional regulation of protein kinase Cδ.
Aoki R; Li YR
Sci Signal; 2011 Oct; 4(195):jc6. PubMed ID: 22009151
[TBL] [Abstract][Full Text] [Related]
14. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
[TBL] [Abstract][Full Text] [Related]
15. Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.
Stoll AC; Kemp CJ; Patterson JR; Howe JW; Steece-Collier K; Luk KC; Sortwell CE; Benskey MJ
Neurobiol Dis; 2024 Feb; 191():106411. PubMed ID: 38228253
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.
Qin H; Buckley JA; Li X; Liu Y; Fox TH; Meares GP; Yu H; Yan Z; Harms AS; Li Y; Standaert DG; Benveniste EN
J Neurosci; 2016 May; 36(18):5144-59. PubMed ID: 27147665
[TBL] [Abstract][Full Text] [Related]
17. Neuroinflammation in Parkinson's Disease and its Treatment Opportunities.
Çınar E; Tel BC; Şahin G
Balkan Med J; 2022 Sep; 39(5):318-333. PubMed ID: 36036436
[TBL] [Abstract][Full Text] [Related]
18. α-Synuclein induces prodromal symptoms of Parkinson's disease via activating TLR2/MyD88/NF-κB pathway in Schwann cells of vagus nerve in a rat model.
Cheng Y; Tong Q; Yuan Y; Song X; Jiang W; Wang Y; Li W; Li Y; Zhang K
J Neuroinflammation; 2023 Feb; 20(1):36. PubMed ID: 36788559
[TBL] [Abstract][Full Text] [Related]
19. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.
Uemura N; Yagi H; Uemura MT; Hatanaka Y; Yamakado H; Takahashi R
Mol Neurodegener; 2018 May; 13(1):21. PubMed ID: 29751824
[TBL] [Abstract][Full Text] [Related]
20. Age-dependent neurodegeneration and neuroinflammation in a genetic A30P/A53T double-mutated α-synuclein mouse model of Parkinson's disease.
Rauschenberger L; Behnke J; Grotemeyer A; Knorr S; Volkmann J; Ip CW
Neurobiol Dis; 2022 Sep; 171():105798. PubMed ID: 35750147
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]