BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 36575184)

  • 1. SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.
    Guo S; Lei X; Chang Y; Zhao J; Wang J; Dong X; Liu Q; Zhang Z; Wang L; Yi D; Ma L; Li Q; Zhang Y; Ding J; Liang C; Li X; Guo F; Wang J; Cen S
    Signal Transduct Target Ther; 2022 Dec; 7(1):400. PubMed ID: 36575184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro.
    Miropolskaya N; Kozlov M; Petushkov I; Prostova M; Pupov D; Esyunina D; Kochetkov S; Kulbachinskiy A
    Biochimie; 2023 Mar; 206():81-88. PubMed ID: 36252889
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plant-Derived Natural Non-Nucleoside Analog Inhibitors (NNAIs) against
    Naidu SAG; Mustafa G; Clemens RA; Naidu AS
    J Diet Suppl; 2023; 20(2):254-283. PubMed ID: 34850656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of replicating SARS-CoV-2 polymerase.
    Hillen HS; Kokic G; Farnung L; Dienemann C; Tegunov D; Cramer P
    Nature; 2020 Aug; 584(7819):154-156. PubMed ID: 32438371
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay.
    Bai X; Sun H; Wu S; Li Y; Wang L; Hong B
    Front Immunol; 2022; 13():844749. PubMed ID: 35464436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fidelity of Ribonucleotide Incorporation by the SARS-CoV-2 Replication Complex.
    Yin X; Popa H; Stapon A; Bouda E; Garcia-Diaz M
    J Mol Biol; 2023 Mar; 435(5):167973. PubMed ID: 36690070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimized Recombinant Expression and Purification of the SARS-CoV-2 Polymerase Complex.
    Podadera A; Campo L; Rehman F; Kolobaric N; Zutic A; Ng KK
    Curr Protoc; 2024 Mar; 4(3):e1007. PubMed ID: 38511495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
    Biswal M; Diggs S; Xu D; Khudaverdyan N; Lu J; Fang J; Blaha G; Hai R; Song J
    Nucleic Acids Res; 2021 Jun; 49(10):5956-5966. PubMed ID: 33999154
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fast and efficient purification of SARS-CoV-2 RNA dependent RNA polymerase complex expressed in Escherichia coli.
    Madru C; Tekpinar AD; Rosario S; Czernecki D; Brûlé S; Sauguet L; Delarue M
    PLoS One; 2021; 16(4):e0250610. PubMed ID: 33914787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
    Wang Q; Wu J; Wang H; Gao Y; Liu Q; Mu A; Ji W; Yan L; Zhu Y; Zhu C; Fang X; Yang X; Huang Y; Gao H; Liu F; Ge J; Sun Q; Yang X; Xu W; Liu Z; Yang H; Lou Z; Jiang B; Guddat LW; Gong P; Rao Z
    Cell; 2020 Jul; 182(2):417-428.e13. PubMed ID: 32526208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATP enhances the error-prone ribonucleotide incorporation by the SARS-CoV-2 RNA polymerase.
    Pourfarjam Y; Ma Z; Kim IK
    Biochem Biophys Res Commun; 2022 Oct; 625():53-59. PubMed ID: 35947915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The E3 ligase TRIM22 restricts SARS-CoV-2 replication by promoting proteasomal degradation of NSP8.
    Fan L; Zhou Y; Wei X; Feng W; Guo H; Li Y; Gao X; Zhou J; Wen Y; Wu Y; Shen X; Liu L; Xu G; Zhang Z
    mBio; 2024 Feb; 15(2):e0232023. PubMed ID: 38275298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
    Chen J; Malone B; Llewellyn E; Grasso M; Shelton PMM; Olinares PDB; Maruthi K; Eng ET; Vatandaslar H; Chait BT; Kapoor TM; Darst SA; Campbell EA
    Cell; 2020 Sep; 182(6):1560-1573.e13. PubMed ID: 32783916
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2.
    Peng Q; Peng R; Yuan B; Zhao J; Wang M; Wang X; Wang Q; Sun Y; Fan Z; Qi J; Gao GF; Shi Y
    Cell Rep; 2020 Jun; 31(11):107774. PubMed ID: 32531208
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics.
    Courouble VV; Dey SK; Yadav R; Timm J; Harrison JJEK; Ruiz FX; Arnold E; Griffin PR
    J Am Soc Mass Spectrom; 2021 Jul; 32(7):1618-1630. PubMed ID: 34121407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19.
    Chien M; Anderson TK; Jockusch S; Tao C; Li X; Kumar S; Russo JJ; Kirchdoerfer RN; Ju J
    J Proteome Res; 2020 Nov; 19(11):4690-4697. PubMed ID: 32692185
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
    Grimes SL; Choi YJ; Banerjee A; Small G; Anderson-Daniels J; Gribble J; Pruijssers AJ; Agostini ML; Abu-Shmais A; Lu X; Darst SA; Campbell E; Denison MR
    mBio; 2023 Aug; 14(4):e0106023. PubMed ID: 37338298
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SARS-CoV-2 variants with NSP12 P323L/G671S mutations display enhanced virus replication in ferret upper airways and higher transmissibility.
    Kim SM; Kim EH; Casel MAB; Kim YI; Sun R; Kwak MJ; Yoo JS; Yu M; Yu KM; Jang SG; Rollon R; Choi JH; Gil J; Eun K; Kim H; Ensser A; Hwang J; Song MS; Kim MH; Jung JU; Choi YK
    Cell Rep; 2023 Sep; 42(9):113077. PubMed ID: 37676771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
    Gordon CJ; Tchesnokov EP; Feng JY; Porter DP; Götte M
    J Biol Chem; 2020 Apr; 295(15):4773-4779. PubMed ID: 32094225
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNA-dependent RNA polymerase of SARS-CoV-2 regulate host mRNA translation efficiency by hijacking eEF1A factors.
    Gan H; Zhou X; Lei Q; Wu L; Niu J; Zheng Q
    Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166871. PubMed ID: 37673357
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.