233 related articles for article (PubMed ID: 36575184)
21. Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivir.
Martin R; Li J; Parvangada A; Perry J; Cihlar T; Mo H; Porter D; Svarovskaia E
Antiviral Res; 2021 Apr; 188():105033. PubMed ID: 33549572
[TBL] [Abstract][Full Text] [Related]
22. Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Malone B; Chen J; Wang Q; Llewellyn E; Choi YJ; Olinares PDB; Cao X; Hernandez C; Eng ET; Chait BT; Shaw DE; Landick R; Darst SA; Campbell EA
Proc Natl Acad Sci U S A; 2021 May; 118(19):. PubMed ID: 33883267
[TBL] [Abstract][Full Text] [Related]
23. Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2.
Machitani M; Takei J; Kaneko MK; Ueki S; Ohashi H; Watashi K; Kato Y; Masutomi K
Virol J; 2022 Dec; 19(1):213. PubMed ID: 36496472
[TBL] [Abstract][Full Text] [Related]
24. Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates.
Ahn DG; Choi JK; Taylor DR; Oh JW
Arch Virol; 2012 Nov; 157(11):2095-104. PubMed ID: 22791111
[TBL] [Abstract][Full Text] [Related]
25. Replication of the coronavirus genome: A paradox among positive-strand RNA viruses.
Grellet E; L'Hôte I; Goulet A; Imbert I
J Biol Chem; 2022 May; 298(5):101923. PubMed ID: 35413290
[TBL] [Abstract][Full Text] [Related]
26. Structural Basis of the Potential Binding Mechanism of Remdesivir to SARS-CoV-2 RNA-Dependent RNA Polymerase.
Zhang L; Zhou R
J Phys Chem B; 2020 Aug; 124(32):6955-6962. PubMed ID: 32521159
[TBL] [Abstract][Full Text] [Related]
27. Mutations in SARS-CoV-2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure.
Reshamwala SMS; Likhite V; Degani MS; Deb SS; Noronha SB
J Med Virol; 2021 Jul; 93(7):4616-4619. PubMed ID: 33433004
[TBL] [Abstract][Full Text] [Related]
28. The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 Pandemic.
Comunale BA; Larson RJ; Jackson-Ward E; Singh A; Koback FL; Engineer LD
Viruses; 2023 Nov; 15(12):. PubMed ID: 38140557
[TBL] [Abstract][Full Text] [Related]
29. Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y; Yan L; Huang Y; Liu F; Zhao Y; Cao L; Wang T; Sun Q; Ming Z; Zhang L; Ge J; Zheng L; Zhang Y; Wang H; Zhu Y; Zhu C; Hu T; Hua T; Zhang B; Yang X; Li J; Yang H; Liu Z; Xu W; Guddat LW; Wang Q; Lou Z; Rao Z
Science; 2020 May; 368(6492):779-782. PubMed ID: 32277040
[TBL] [Abstract][Full Text] [Related]
30. Effects of natural RNA modifications on the activity of SARS-CoV-2 RNA-dependent RNA polymerase.
Petushkov I; Esyunina D; Kulbachinskiy A
FEBS J; 2023 Jan; 290(1):80-92. PubMed ID: 35916766
[TBL] [Abstract][Full Text] [Related]
31. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase.
Bertolin AP; Weissmann F; Zeng J; Posse V; Milligan JC; Canal B; Ulferts R; Wu M; Drury LS; Howell M; Beale R; Diffley JFX
Biochem J; 2021 Jul; 478(13):2425-2443. PubMed ID: 34198323
[TBL] [Abstract][Full Text] [Related]
32. A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase.
Zhao J; Guo S; Yi D; Li Q; Ma L; Zhang Y; Wang J; Li X; Guo F; Lin R; Liang C; Liu Z; Cen S
Antiviral Res; 2021 Jun; 190():105078. PubMed ID: 33894278
[TBL] [Abstract][Full Text] [Related]
33. SARS-CoV-2 NSP12 utilizes various host splicing factors for replication and splicing regulation.
Yang L; Zeng XT; Luo RH; Ren SX; Liang LL; Huang QX; Tang Y; Fan H; Ren HY; Zhang WJ; Zheng YT; Cheng W
J Med Virol; 2024 Jan; 96(1):e29396. PubMed ID: 38235848
[TBL] [Abstract][Full Text] [Related]
34. A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Shannon A; Fattorini V; Sama B; Selisko B; Feracci M; Falcou C; Gauffre P; El Kazzi P; Delpal A; Decroly E; Alvarez K; Eydoux C; Guillemot JC; Moussa A; Good SS; La Colla P; Lin K; Sommadossi JP; Zhu Y; Yan X; Shi H; Ferron F; Canard B
Nat Commun; 2022 Feb; 13(1):621. PubMed ID: 35110538
[TBL] [Abstract][Full Text] [Related]
35. RNA-dependent RNA polymerase of SARS-CoV-2 as a therapeutic target.
Wang Y; Anirudhan V; Du R; Cui Q; Rong L
J Med Virol; 2021 Jan; 93(1):300-310. PubMed ID: 32633831
[TBL] [Abstract][Full Text] [Related]
36. Phylogenetic Analysis and Structural Perspectives of RNA-Dependent RNA-Polymerase Inhibition from SARs-CoV-2 with Natural Products.
Khan A; Khan M; Saleem S; Babar Z; Ali A; Khan AA; Sardar Z; Hamayun F; Ali SS; Wei DQ
Interdiscip Sci; 2020 Sep; 12(3):335-348. PubMed ID: 32617855
[TBL] [Abstract][Full Text] [Related]
37. Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication.
Zhang X; Hao H; Ma L; Zhang Y; Hu X; Chen Z; Liu D; Yuan J; Hu Z; Guan W
mBio; 2021 Aug; 12(4):e0106721. PubMed ID: 34225491
[TBL] [Abstract][Full Text] [Related]
38. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency.
Gordon CJ; Tchesnokov EP; Woolner E; Perry JK; Feng JY; Porter DP; Götte M
J Biol Chem; 2020 May; 295(20):6785-6797. PubMed ID: 32284326
[TBL] [Abstract][Full Text] [Related]
39. In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs.
Mondal SK; Mukhoty S; Kundu H; Ghosh S; Sen MK; Das S; Brogi S
Comput Biol Med; 2021 Aug; 135():104591. PubMed ID: 34216889
[TBL] [Abstract][Full Text] [Related]
40. Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.
Sexton NR; Smith EC; Blanc H; Vignuzzi M; Peersen OB; Denison MR
J Virol; 2016 Aug; 90(16):7415-7428. PubMed ID: 27279608
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]