BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 36576236)

  • 1. Frequent loss of metastatic ability in subclones of Apc, Kras, Tgfbr2, and Trp53 mutant intestinal tumor organoids.
    Morita A; Nakayama M; Wang D; Murakami K; Oshima M
    Cancer Sci; 2023 Apr; 114(4):1437-1450. PubMed ID: 36576236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined Mutation of
    Sakai E; Nakayama M; Oshima H; Kouyama Y; Niida A; Fujii S; Ochiai A; Nakayama KI; Mimori K; Suzuki Y; Hong CP; Ock CY; Kim SJ; Oshima M
    Cancer Res; 2018 Mar; 78(5):1334-1346. PubMed ID: 29282223
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In Vitro and In Vivo Models for Metastatic Intestinal Tumors Using Genotype-Defined Organoids.
    Morita A; Nakayama M; Oshima H; Oshima M
    Methods Mol Biol; 2023; 2691():19-30. PubMed ID: 37355534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation.
    Nakayama M; Sakai E; Echizen K; Yamada Y; Oshima H; Han TS; Ohki R; Fujii S; Ochiai A; Robine S; Voon DC; Tanaka T; Taketo MM; Oshima M
    Oncogene; 2017 Oct; 36(42):5885-5896. PubMed ID: 28628120
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance.
    Wong CC; Xu J; Bian X; Wu JL; Kang W; Qian Y; Li W; Chen H; Gou H; Liu D; Yat Luk ST; Zhou Q; Ji F; Chan LS; Shirasawa S; Sung JJ; Yu J
    Gastroenterology; 2020 Dec; 159(6):2163-2180.e6. PubMed ID: 32814111
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
    Joosten SPJ; Zeilstra J; van Andel H; Mijnals RC; Zaunbrecher J; Duivenvoorden AAM; van de Wetering M; Clevers H; Spaargaren M; Pals ST
    Gastroenterology; 2017 Oct; 153(4):1040-1053.e4. PubMed ID: 28716720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
    Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
    Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic KRAS-expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice.
    Kasuga A; Semba T; Sato R; Nobusue H; Sugihara E; Takaishi H; Kanai T; Saya H; Arima Y
    Cancer Sci; 2021 May; 112(5):1822-1838. PubMed ID: 33068050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation and analysis of mouse intestinal tumors and organoids harboring APC and K-Ras mutations.
    van Es JH; Clevers H
    Methods Mol Biol; 2015; 1267():125-44. PubMed ID: 25636467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequential cancer mutations in cultured human intestinal stem cells.
    Drost J; van Jaarsveld RH; Ponsioen B; Zimberlin C; van Boxtel R; Buijs A; Sachs N; Overmeer RM; Offerhaus GJ; Begthel H; Korving J; van de Wetering M; Schwank G; Logtenberg M; Cuppen E; Snippert HJ; Medema JP; Kops GJ; Clevers H
    Nature; 2015 May; 521(7550):43-7. PubMed ID: 25924068
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nano-scale physical properties characteristic to metastatic intestinal cancer cells identified by high-speed scanning ion conductance microscope.
    Wang D; Sun L; Okuda S; Yamamoto D; Nakayama M; Oshima H; Saito H; Kouyama Y; Mimori K; Ando T; Watanabe S; Oshima M
    Biomaterials; 2022 Jan; 280():121256. PubMed ID: 34794825
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
    Davies EJ; Marsh Durban V; Meniel V; Williams GT; Clarke AR
    J Pathol; 2014 May; 233(1):27-38. PubMed ID: 24293351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
    Wiener Z; Band AM; Kallio P; Högström J; Hyvönen V; Kaijalainen S; Ritvos O; Haglund C; Kruuna O; Robine S; Louvard D; Ben-Neriah Y; Alitalo K
    Proc Natl Acad Sci U S A; 2014 May; 111(21):E2229-36. PubMed ID: 24825889
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids.
    Nakaoka T; Saito Y; Shimamoto Y; Muramatsu T; Kimura M; Kanai Y; Saito H
    Cancer Sci; 2017 Apr; 108(4):678-684. PubMed ID: 28092415
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant p53 in colon cancer.
    Nakayama M; Oshima M
    J Mol Cell Biol; 2019 Apr; 11(4):267-276. PubMed ID: 30496442
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes.
    Takeda H; Kataoka S; Nakayama M; Ali MAE; Oshima H; Yamamoto D; Park JW; Takegami Y; An T; Jenkins NA; Copeland NG; Oshima M
    Proc Natl Acad Sci U S A; 2019 Jul; 116(31):15635-15644. PubMed ID: 31300537
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis.
    Matsuura T; Maru Y; Izumiya M; Hoshi D; Kato S; Ochiai M; Hori M; Yamamoto S; Tatsuno K; Imai T; Aburatani H; Nakajima A; Hippo Y
    Carcinogenesis; 2020 Jun; 41(4):490-501. PubMed ID: 31233118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer.
    Yamasaki J; Hirata Y; Otsuki Y; Suina K; Saito Y; Masuda K; Okazaki S; Ishimoto T; Saya H; Nagano O
    Cancer Sci; 2022 Mar; 113(3):916-925. PubMed ID: 34931404
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.
    Luo F; Brooks DG; Ye H; Hamoudi R; Poulogiannis G; Patek CE; Winton DJ; Arends MJ
    Int J Exp Pathol; 2009 Oct; 90(5):558-74. PubMed ID: 19765110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer.
    Oshima H; Nakayama M; Han TS; Naoi K; Ju X; Maeda Y; Robine S; Tsuchiya K; Sato T; Sato H; Taketo MM; Oshima M
    Cancer Res; 2015 Feb; 75(4):766-76. PubMed ID: 25687406
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.