These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 36576708)

  • 1. The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities.
    Brandimarti R; Irollo E; Meucci O
    Mol Neurobiol; 2023 Apr; 60(4):1811-1825. PubMed ID: 36576708
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The lipid raft-dwelling protein US9 can be manipulated to target APP compartmentalization, APP processing, and neurodegenerative disease pathogenesis.
    Brandimarti R; Hill GS; Geiger JD; Meucci O
    Sci Rep; 2017 Nov; 7(1):15103. PubMed ID: 29118375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular Trafficking of Amyloid Precursor Protein in Amyloidogenesis Physiological and Pathological Significance.
    Mañucat-Tan NB; Saadipour K; Wang YJ; Bobrovskaya L; Zhou XF
    Mol Neurobiol; 2019 Feb; 56(2):812-830. PubMed ID: 29797184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
    Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
    Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of Non-Amyloidogenic Mutations in APP Supports Loss of Function Hypothesis of Alzheimer's Disease.
    Kim M; Bezprozvanny I
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation and targeting of amyloid precursor protein (APP)/amyloid beta (Aβ) axis in amyloidogenic and non-amyloidogenic pathways: A time outside the tunnel.
    Al-Kuraishy HM; Jabir MS; Al-Gareeb AI; Albuhadily AK; Albukhaty S; Sulaiman GM; Batiha GE
    Ageing Res Rev; 2023 Dec; 92():102119. PubMed ID: 37931848
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis.
    Sun J; Roy S
    Dev Neurobiol; 2018 Mar; 78(3):340-347. PubMed ID: 29106038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta.
    Lopez Sanchez MIG; Waugh HS; Tsatsanis A; Wong BX; Crowston JG; Duce JA; Trounce IA
    Sci Rep; 2017 Aug; 7(1):9835. PubMed ID: 28852095
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease.
    Al-Atrache Z; Lopez DB; Hingley ST; Appelt DM
    BMC Neurosci; 2019 Feb; 20(1):6. PubMed ID: 30786875
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease.
    Tan JZA; Gleeson PA
    Biochim Biophys Acta Biomembr; 2019 Apr; 1861(4):697-712. PubMed ID: 30639513
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Super-Resolved View of the Alzheimer's Disease-Related Amyloidogenic Pathway in Hippocampal Neurons.
    Yu Y; Gao Y; Winblad B; Tjernberg LO; Schedin-Weiss S
    J Alzheimers Dis; 2021; 83(2):833-852. PubMed ID: 34366358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations.
    McPhie DL; Golde T; Eckman CB; Yager D; Brant JB; Neve RL
    Brain Res Mol Brain Res; 2001 Dec; 97(1):103-13. PubMed ID: 11744168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
    Pitsi D; Kienlen-Campard P; Octave JN
    J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb.
    Sun M; Asghar SZ; Zhang H
    Neurobiol Dis; 2016 Sep; 93():1-11. PubMed ID: 27072891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production.
    Gerber H; Wu F; Dimitrov M; Garcia Osuna GM; Fraering PC
    J Biol Chem; 2017 Mar; 292(9):3751-3767. PubMed ID: 28096459
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alzheimer's disease.
    De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
    Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides.
    Siegel G; Gerber H; Koch P; Bruestle O; Fraering PC; Rajendran L
    Cell Rep; 2017 Jun; 19(10):1967-1976. PubMed ID: 28591569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.