These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 36586153)

  • 1. The loop diuretic torasemide but not azosemide potentiates the anti-seizure and disease-modifying effects of midazolam in a rat model of birth asphyxia.
    Welzel B; Schmidt R; Kirchhoff L; Gramer M; Löscher W
    Epilepsy Behav; 2023 Feb; 139():109057. PubMed ID: 36586153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the NKCC1 inhibitors bumetanide, azosemide, and torasemide alone or in combination with phenobarbital on seizure threshold in epileptic and nonepileptic mice.
    Hampel P; Römermann K; Gailus B; Johne M; Gericke B; Kaczmarek E; Löscher W
    Neuropharmacology; 2021 Mar; 185():108449. PubMed ID: 33450274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bumetanide potentiates the anti-seizure and disease-modifying effects of midazolam in a noninvasive rat model of term birth asphyxia.
    Welzel B; Johne M; Löscher W
    Epilepsy Behav; 2023 May; 142():109189. PubMed ID: 37037061
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The search for brain-permeant NKCC1 inhibitors for the treatment of seizures: Pharmacokinetic-pharmacodynamic modelling of NKCC1 inhibition by azosemide, torasemide, and bumetanide in mouse brain.
    Hampel P; Römermann K; Gramer M; Löscher W
    Epilepsy Behav; 2021 Jan; 114(Pt A):107616. PubMed ID: 33279441
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy.
    Brandt C; Seja P; Töllner K; Römermann K; Hampel P; Kalesse M; Kipper A; Feit PW; Lykke K; Toft-Bertelsen TL; Paavilainen P; Spoljaric I; Puskarjov M; MacAulay N; Kaila K; Löscher W
    Neuropharmacology; 2018 Dec; 143():186-204. PubMed ID: 30248303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B.
    Hampel P; Römermann K; MacAulay N; Löscher W
    Sci Rep; 2018 Jun; 8(1):9877. PubMed ID: 29959396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CNS pharmacology of NKCC1 inhibitors.
    Löscher W; Kaila K
    Neuropharmacology; 2022 Mar; 205():108910. PubMed ID: 34883135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phenobarbital and midazolam suppress neonatal seizures in a noninvasive rat model of birth asphyxia, whereas bumetanide is ineffective.
    Johne M; Römermann K; Hampel P; Gailus B; Theilmann W; Ala-Kurikka T; Kaila K; Löscher W
    Epilepsia; 2021 Apr; 62(4):920-934. PubMed ID: 33258158
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo effects of bumetanide at brain concentrations incompatible with NKCC1 inhibition on newborn DGC structure and spontaneous EEG seizures following hypoxia-induced neonatal seizures.
    Wang S; Zhang XQ; Song CG; Xiao T; Zhao M; Zhu G; Zhao CS
    Neuroscience; 2015 Feb; 286():203-15. PubMed ID: 25463517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A combination of phenobarbital and the bumetanide derivative bumepamine prevents neonatal seizures and subsequent hippocampal neurodegeneration in a rat model of birth asphyxia.
    Johne M; Käufer C; Römermann K; Gailus B; Gericke B; Löscher W
    Epilepsia; 2021 Jun; 62(6):1460-1471. PubMed ID: 33955541
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NKCC1 transporter facilitates seizures in the developing brain.
    Dzhala VI; Talos DM; Sdrulla DA; Brumback AC; Mathews GC; Benke TA; Delpire E; Jensen FE; Staley KJ
    Nat Med; 2005 Nov; 11(11):1205-13. PubMed ID: 16227993
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs.
    Hannaert P; Alvarez-Guerra M; Pirot D; Nazaret C; Garay RP
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Mar; 365(3):193-9. PubMed ID: 11882915
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Consequences of inhibition of bumetanide metabolism in rodents on brain penetration and effects of bumetanide in chronic models of epilepsy.
    Töpfer M; Töllner K; Brandt C; Twele F; Bröer S; Löscher W
    Eur J Neurosci; 2014 Feb; 39(4):673-87. PubMed ID: 24251546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure - A multicenter propensity score matched analysis.
    Täger T; Fröhlich H; Grundtvig M; Seiz M; Schellberg D; Goode K; Kazmi S; Hole T; Katus HA; Atar D; Cleland JGF; Agewall S; Clark AL; Frankenstein L
    Int J Cardiol; 2019 Aug; 289():83-90. PubMed ID: 30827731
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reply to the commentary by Ben-Ari and Delpire: Bumetanide and neonatal seizures: Fiction versus reality.
    Löscher W; Kaila K
    Epilepsia; 2021 Apr; 62(4):941-946. PubMed ID: 33764535
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel.
    Kaila K; Löscher W
    Epilepsia; 2022 Jul; 63(7):1868-1873. PubMed ID: 35524446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.
    Cleary RT; Sun H; Huynh T; Manning SM; Li Y; Rotenberg A; Talos DM; Kahle KT; Jackson M; Rakhade SN; Berry G; Jensen FE
    PLoS One; 2013; 8(3):e57148. PubMed ID: 23536761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterogeneous brain distribution of bumetanide following systemic administration in rats.
    Löscher W; Gramer M; Römermann K
    Biopharm Drug Dispos; 2024 Jun; 45(3):138-148. PubMed ID: 38823029
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures.
    Kahle KT; Staley KJ
    Neurosurg Focus; 2008 Sep; 25(3):E22. PubMed ID: 18759624
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
    Dzhala VI; Brumback AC; Staley KJ
    Ann Neurol; 2008 Feb; 63(2):222-35. PubMed ID: 17918265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.