130 related articles for article (PubMed ID: 36586301)
1. Sequence and structure-guided discovery of a novel NADH-dependent 7β-hydroxysteroid dehydrogenase for efficient biosynthesis of ursodeoxycholic acid.
Huang B; Yang K; Amanze C; Yan Z; Zhou H; Liu X; Qiu G; Zeng W
Bioorg Chem; 2023 Feb; 131():106340. PubMed ID: 36586301
[TBL] [Abstract][Full Text] [Related]
2. Machine-Learning-Guided Engineering of an NADH-Dependent 7β-Hydroxysteroid Dehydrogenase for Economic Synthesis of Ursodeoxycholic Acid.
Wang MQ; You ZN; Yang BY; Xia ZW; Chen Q; Pan J; Li CX; Xu JH
J Agric Food Chem; 2023 Dec; 71(49):19672-19681. PubMed ID: 38016669
[TBL] [Abstract][Full Text] [Related]
3. Engineering 7β-Hydroxysteroid Dehydrogenase for Enhanced Ursodeoxycholic Acid Production by Multiobjective Directed Evolution.
Zheng MM; Chen KC; Wang RF; Li H; Li CX; Xu JH
J Agric Food Chem; 2017 Feb; 65(6):1178-1185. PubMed ID: 28116898
[TBL] [Abstract][Full Text] [Related]
4. Structure of NADP
Wang R; Wu J; Jin DK; Chen Y; Lv Z; Chen Q; Miao Q; Huo X; Wang F
Acta Crystallogr F Struct Biol Commun; 2017 May; 73(Pt 5):246-252. PubMed ID: 28471355
[TBL] [Abstract][Full Text] [Related]
5. Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon.
Lee JY; Arai H; Nakamura Y; Fukiya S; Wada M; Yokota A
J Lipid Res; 2013 Nov; 54(11):3062-9. PubMed ID: 23729502
[TBL] [Abstract][Full Text] [Related]
6. Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens.
Liu L; Aigner A; Schmid RD
Appl Microbiol Biotechnol; 2011 Apr; 90(1):127-35. PubMed ID: 21181147
[TBL] [Abstract][Full Text] [Related]
7. NAD
Tonin F; Otten LG; Arends IWCE
ChemSusChem; 2019 Jul; 12(13):3192-3203. PubMed ID: 30265441
[TBL] [Abstract][Full Text] [Related]
8. One-step synthesis of 12-ketoursodeoxycholic acid from dehydrocholic acid using a multienzymatic system.
Liu L; Braun M; Gebhardt G; Weuster-Botz D; Gross R; Schmid RD
Appl Microbiol Biotechnol; 2013 Jan; 97(2):633-9. PubMed ID: 22899496
[TBL] [Abstract][Full Text] [Related]
9. Novel whole-cell biocatalysts with recombinant hydroxysteroid dehydrogenases for the asymmetric reduction of dehydrocholic acid.
Braun M; Sun B; Anselment B; Weuster-Botz D
Appl Microbiol Biotechnol; 2012 Sep; 95(6):1457-68. PubMed ID: 22581067
[TBL] [Abstract][Full Text] [Related]
10. Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
Zhang X; Fan D; Hua X; Zhang T
Bioprocess Biosyst Eng; 2019 Sep; 42(9):1537-1545. PubMed ID: 31152232
[TBL] [Abstract][Full Text] [Related]
11. Multi-enzymatic one-pot reduction of dehydrocholic acid to 12-keto-ursodeoxycholic acid with whole-cell biocatalysts.
Sun B; Kantzow C; Bresch S; Castiglione K; Weuster-Botz D
Biotechnol Bioeng; 2013 Jan; 110(1):68-77. PubMed ID: 22806613
[TBL] [Abstract][Full Text] [Related]
12. Continuous Production of Ursodeoxycholic Acid by Using Two Cascade Reactors with Co-immobilized Enzymes.
Zheng MM; Chen FF; Li H; Li CX; Xu JH
Chembiochem; 2018 Feb; 19(4):347-353. PubMed ID: 28926166
[TBL] [Abstract][Full Text] [Related]
13. Xanthomonas maltophilia CBS 897.97 as a source of new 7beta- and 7alpha-hydroxysteroid dehydrogenases and cholylglycine hydrolase: improved biotransformations of bile acids.
Pedrini P; Andreotti E; Guerrini A; Dean M; Fantin G; Giovannini PP
Steroids; 2006 Mar; 71(3):189-98. PubMed ID: 16307764
[TBL] [Abstract][Full Text] [Related]
14. Enzymatic routes for the synthesis of ursodeoxycholic acid.
Eggert T; Bakonyi D; Hummel W
J Biotechnol; 2014 Dec; 191():11-21. PubMed ID: 25131646
[TBL] [Abstract][Full Text] [Related]
15. Targeted Synthesis and Characterization of a Gene Cluster Encoding NAD(P)H-Dependent 3α-, 3β-, and 12α-Hydroxysteroid Dehydrogenases from Eggerthella CAG:298, a Gut Metagenomic Sequence.
Mythen SM; Devendran S; Méndez-García C; Cann I; Ridlon JM
Appl Environ Microbiol; 2018 Apr; 84(7):. PubMed ID: 29330189
[TBL] [Abstract][Full Text] [Related]
16. In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum.
Ferrandi EE; Bertolesi GM; Polentini F; Negri A; Riva S; Monti D
Appl Microbiol Biotechnol; 2012 Sep; 95(5):1221-33. PubMed ID: 22198717
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria.
Doden H; Sallam LA; Devendran S; Ly L; Doden G; Daniel SL; Alves JMP; Ridlon JM
Appl Environ Microbiol; 2018 May; 84(10):. PubMed ID: 29549099
[TBL] [Abstract][Full Text] [Related]
18. Enhanced activity and substrate tolerance of 7α-hydroxysteroid dehydrogenase by directed evolution for 7-ketolithocholic acid production.
Huang B; Zhao Q; Zhou JH; Xu G
Appl Microbiol Biotechnol; 2019 Mar; 103(6):2665-2674. PubMed ID: 30734123
[TBL] [Abstract][Full Text] [Related]
19. Dynamic mechanistic modeling of the multienzymatic one-pot reduction of dehydrocholic acid to 12-keto ursodeoxycholic acid with competing substrates and cofactors.
Sun B; Hartl F; Castiglione K; Weuster-Botz D
Biotechnol Prog; 2015; 31(2):375-86. PubMed ID: 25641915
[TBL] [Abstract][Full Text] [Related]
20. Discovery of tauroursodeoxycholic acid biotransformation enzymes from the gut microbiome of black bears using metagenomics.
Song C; Wang B; Tan J; Zhu L; Lou D
Sci Rep; 2017 Apr; 7():45495. PubMed ID: 28436439
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]