BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 36587872)

  • 1. Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor.
    Decker AM; Rahman MT; Kormos CM; Hesk D; Darcq E; Kieffer BL; Jin C
    Bioorg Med Chem Lett; 2023 Jan; 80():129120. PubMed ID: 36587872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.
    Rahman MT; Decker AM; Ben Hamida S; Perrey DA; Chaminda Lakmal HH; Maitra R; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2023 Feb; 66(4):2964-2978. PubMed ID: 36749855
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88.
    Decker AM; Gay EA; Mathews KM; Rosa TC; Langston TL; Maitra R; Jin C
    J Biomed Sci; 2017 Mar; 24(1):23. PubMed ID: 28347302
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor.
    Jin C; Decker AM; Huang XP; Gilmour BP; Blough BE; Roth BL; Hu Y; Gill JB; Zhang XP
    ACS Chem Neurosci; 2014 Jul; 5(7):576-87. PubMed ID: 24793972
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists.
    Jin C; Decker AM; Langston TL
    Bioorg Med Chem; 2017 Jan; 25(2):805-812. PubMed ID: 27956039
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.
    Rahman MT; Decker AM; Langston TL; Mathews KM; Laudermilk L; Maitra R; Ma W; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2020 Dec; 63(23):14989-15012. PubMed ID: 33205975
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target.
    Ye N; Li B; Mao Q; Wold EA; Tian S; Allen JA; Zhou J
    ACS Chem Neurosci; 2019 Jan; 10(1):190-200. PubMed ID: 30540906
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The GPR88 agonist RTI-13951-33 reduces alcohol drinking and seeking in mice.
    Ben Hamida S; Carter M; Darcq E; Sourty M; Rahman MT; Decker AM; Jin C; Kieffer BL
    Addict Biol; 2022 Nov; 27(6):e13227. PubMed ID: 36301207
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.
    Köse M; Pillaiyar T; Namasivayam V; De Filippo E; Sylvester K; Ulven T; von Kügelgen I; Müller CE
    J Med Chem; 2020 Mar; 63(5):2391-2410. PubMed ID: 31721581
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and pharmacological evaluation of [(3)H]HS665, a novel, highly selective radioligand for the kappa opioid receptor.
    Guerrieri E; Mallareddy JR; Tóth G; Schmidhammer H; Spetea M
    ACS Chem Neurosci; 2015 Mar; 6(3):456-63. PubMed ID: 25496417
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, Synthesis, and Structure-Activity Relationship Studies of Novel GPR88 Agonists (4-Substituted-phenyl)acetamides Based on the Reversed Amide Scaffold.
    Rahman MT; Guan D; Chaminda Lakmal HH; Decker AM; Imler GH; Kerr AT; Harris DL; Jin C
    ACS Chem Neurosci; 2024 Jan; 15(1):169-192. PubMed ID: 38086012
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.
    Jin C; Decker AM; Harris DL; Blough BE
    ACS Chem Neurosci; 2016 Oct; 7(10):1418-1432. PubMed ID: 27499251
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.
    Rahman MT; Decker AM; Laudermilk L; Maitra R; Ma W; Ben Hamida S; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2021 Aug; 64(16):12397-12413. PubMed ID: 34387471
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Orphan receptor GPR88 as a potential therapeutic target for CNS disorders - an
    Garisetti V; Dhanabalan AK; Dasararaju G
    J Biomol Struct Dyn; 2024 Jun; 42(9):4745-4758. PubMed ID: 37306437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake.
    Jin C; Decker AM; Makhijani VH; Besheer J; Darcq E; Kieffer BL; Maitra R
    J Med Chem; 2018 Aug; 61(15):6748-6758. PubMed ID: 30011199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.
    Ioja E; Tourwé D; Kertész I; Tóth G; Borsodi A; Benyhe S
    Brain Res Bull; 2007 Sep; 74(1-3):119-29. PubMed ID: 17683797
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Radioligand binding methods for membrane preparations and intact cells.
    Bylund DB; Toews ML
    Methods Mol Biol; 2011; 746():135-64. PubMed ID: 21607856
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284.
    Smith DL; Davoren JE; Edgerton JR; Lazzaro JT; Lee CW; Neal S; Zhang L; Grimwood S
    Mol Pharmacol; 2016 Sep; 90(3):177-87. PubMed ID: 27382013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.
    Ehrlich AT; Semache M; Bailly J; Wojcik S; Arefin TM; Colley C; Le Gouill C; Gross F; Lukasheva V; Hogue M; Darcq E; Harsan LA; Bouvier M; Kieffer BL
    Brain Struct Funct; 2018 Apr; 223(3):1275-1296. PubMed ID: 29110094
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective and high affinity labeling of neuronal and recombinant nociceptin receptors with the hexapeptide radioprobe [(3)H]Ac-RYYRIK-ol.
    Bojnik E; Farkas J; Magyar A; Tömböly C; Güçlü U; Gündüz O; Borsodi A; Corbani M; Benyhe S
    Neurochem Int; 2009 Dec; 55(7):458-66. PubMed ID: 19414055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.