These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 36599980)

  • 1. RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
    Bravo JPK; Hallmark T; Naegle B; Beisel CL; Jackson RN; Taylor DW
    Nature; 2023 Jan; 613(7944):582-587. PubMed ID: 36599980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.
    Dmytrenko O; Neumann GC; Hallmark T; Keiser DJ; Crowley VM; Vialetto E; Mougiakos I; Wandera KG; Domgaard H; Weber J; Gaudin T; Metcalf J; Gray BN; Begemann MB; Jackson RN; Beisel CL
    Nature; 2023 Jan; 613(7944):588-594. PubMed ID: 36599979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
    Chen JS; Ma E; Harrington LB; Da Costa M; Tian X; Palefsky JM; Doudna JA
    Science; 2018 Apr; 360(6387):436-439. PubMed ID: 29449511
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
    Sternberg SH; Redding S; Jinek M; Greene EC; Doudna JA
    Nature; 2014 Mar; 507(7490):62-7. PubMed ID: 24476820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms for target recognition and cleavage by the Cas12i RNA-guided endonuclease.
    Zhang H; Li Z; Xiao R; Chang L
    Nat Struct Mol Biol; 2020 Nov; 27(11):1069-1076. PubMed ID: 32895556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
    Gong B; Shin M; Sun J; Jung CH; Bolt EL; van der Oost J; Kim JS
    Proc Natl Acad Sci U S A; 2014 Nov; 111(46):16359-64. PubMed ID: 25368186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a.
    Sundaresan R; Parameshwaran HP; Yogesha SD; Keilbarth MW; Rajan R
    Cell Rep; 2017 Dec; 21(13):3728-3739. PubMed ID: 29281823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conservation and variability in the structure and function of the Cas5d endoribonuclease in the CRISPR-mediated microbial immune system.
    Koo Y; Ka D; Kim EJ; Suh N; Bae E
    J Mol Biol; 2013 Oct; 425(20):3799-810. PubMed ID: 23500492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity.
    He L; Matošević ZJ; Mitić D; Markulin D; Killelea T; Matković M; Bertoša B; Ivančić-Baće I; Bolt EL
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33799639
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
    Guo TW; Bartesaghi A; Yang H; Falconieri V; Rao P; Merk A; Eng ET; Raczkowski AM; Fox T; Earl LA; Patel DJ; Subramaniam S
    Cell; 2017 Oct; 171(2):414-426.e12. PubMed ID: 28985564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems.
    Fonfara I; Le Rhun A; Chylinski K; Makarova KS; Lécrivain AL; Bzdrenga J; Koonin EV; Charpentier E
    Nucleic Acids Res; 2014 Feb; 42(4):2577-90. PubMed ID: 24270795
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamic mechanisms of CRISPR interference by Escherichia coli CRISPR-Cas3.
    Yoshimi K; Takeshita K; Kodera N; Shibumura S; Yamauchi Y; Omatsu M; Umeda K; Kunihiro Y; Yamamoto M; Mashimo T
    Nat Commun; 2022 Aug; 13(1):4917. PubMed ID: 36042215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Card1 nuclease provides defence during type III CRISPR immunity.
    Rostøl JT; Xie W; Kuryavyi V; Maguin P; Kao K; Froom R; Patel DJ; Marraffini LA
    Nature; 2021 Feb; 590(7847):624-629. PubMed ID: 33461211
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosa.
    Rollins MF; Schuman JT; Paulus K; Bukhari HS; Wiedenheft B
    Nucleic Acids Res; 2015 Feb; 43(4):2216-22. PubMed ID: 25662606
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of the Csm1 subunit of the Csm complex and its single-stranded DNA-specific nuclease activity.
    Jung TY; An Y; Park KH; Lee MH; Oh BH; Woo E
    Structure; 2015 Apr; 23(4):782-90. PubMed ID: 25773141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
    Xiao R; Li Z; Wang S; Han R; Chang L
    Nucleic Acids Res; 2021 Apr; 49(7):4120-4128. PubMed ID: 33764415
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
    Schwartz EA; Bravo JPK; Ahsan M; Macias LA; McCafferty CL; Dangerfield TL; Walker JN; Brodbelt JS; Palermo G; Fineran PC; Fagerlund RD; Taylor DW
    Nat Commun; 2024 Apr; 15(1):3324. PubMed ID: 38637512
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
    Jungfer K; Sigg A; Jinek M
    Nucleic Acids Res; 2024 Jan; 52(1):462-473. PubMed ID: 38033326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structural biology of CRISPR-Cas systems.
    Jiang F; Doudna JA
    Curr Opin Struct Biol; 2015 Feb; 30():100-111. PubMed ID: 25723899
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
    Jianwei L; Jobichen C; Machida S; Meng S; Read RJ; Hongying C; Jian S; Yuan YA; Sivaraman J
    PLoS Biol; 2023 Mar; 21(3):e3002023. PubMed ID: 36917574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.