BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 36622698)

  • 61. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation.
    Denoyelle C; Lambert B; Meryet-Figuière M; Vigneron N; Brotin E; Lecerf C; Abeilard E; Giffard F; Louis MH; Gauduchon P; Juin P; Poulain L
    Cell Death Dis; 2014 Oct; 5(10):e1445. PubMed ID: 25299770
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Tyrosine Kinase Inhibitors Increase MCL1 Degradation and in Combination with BCLXL/BCL2 Inhibitors Drive Prostate Cancer Apoptosis.
    Arai S; Jonas O; Whitman MA; Corey E; Balk SP; Chen S
    Clin Cancer Res; 2018 Nov; 24(21):5458-5470. PubMed ID: 30021909
    [No Abstract]   [Full Text] [Related]  

  • 63. The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition.
    Peddaboina C; Jupiter D; Fletcher S; Yap JL; Rai A; Tobin RP; Jiang W; Rascoe P; Rogers MK; Smythe WR; Cao X
    BMC Cancer; 2012 Nov; 12():541. PubMed ID: 23171055
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.
    Cheng C; Liu Y; Balasis ME; Garner TP; Li J; Simmons NL; Berndt N; Song H; Pan L; Qin Y; Nicolaou KC; Gavathiotis E; Sebti SM; Li R
    Mar Drugs; 2014 Jul; 12(8):4311-25. PubMed ID: 25076060
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro.
    Guo L; Eldridge S; Furniss M; Mussio J; Davis M
    Toxicol Appl Pharmacol; 2018 Dec; 360():88-98. PubMed ID: 30268579
    [TBL] [Abstract][Full Text] [Related]  

  • 66. BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer.
    Ramesh P; Lannagan TRM; Jackstadt R; Atencia Taboada L; Lansu N; Wirapati P; van Hooff SR; Dekker D; Pritchard J; Kirov AB; van Neerven SM; Tejpar S; Kops GJPL; Sansom OJ; Medema JP
    Cell Death Differ; 2021 Dec; 28(12):3282-3296. PubMed ID: 34117376
    [TBL] [Abstract][Full Text] [Related]  

  • 67. An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1.
    Zhang Z; Liu Y; Song T; Xue Z; Shen X; Liang F; Zhao Y; Li Z; Sheng H
    Br J Cancer; 2013 May; 108(9):1870-8. PubMed ID: 23558901
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma.
    Zhang Y; Ishida CT; Shu C; Kleiner G; Sanchez-Quintero MJ; Bianchetti E; Quinzii CM; Westhoff MA; Karpel-Massler G; Siegelin MD
    Sci Rep; 2018 May; 8(1):7373. PubMed ID: 29743557
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737.
    Oakes SR; Vaillant F; Lim E; Lee L; Breslin K; Feleppa F; Deb S; Ritchie ME; Takano E; Ward T; Fox SB; Generali D; Smyth GK; Strasser A; Huang DC; Visvader JE; Lindeman GJ
    Proc Natl Acad Sci U S A; 2012 Feb; 109(8):2766-71. PubMed ID: 21768359
    [TBL] [Abstract][Full Text] [Related]  

  • 70. NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.
    Casanelles E; Gozzelino R; Marqués-Fernández F; Iglesias-Guimarais V; Garcia-Belinchón M; Sánchez-Osuna M; Solé C; Moubarak RS; Comella JX; Yuste VJ
    Biochim Biophys Acta; 2013 May; 1833(5):1085-95. PubMed ID: 23369735
    [TBL] [Abstract][Full Text] [Related]  

  • 71. The small-molecule compound BM-1197 inhibits the antiapoptotic regulators Bcl-2/Bcl-xL and triggers apoptotic cell death in human colorectal cancer cells.
    Ye L; Yuan G; Xu F; Sun Y; Chen Z; Chen M; Li T; Sun P; Li S; Sun J
    Tumour Biol; 2015 May; 36(5):3447-55. PubMed ID: 25542230
    [TBL] [Abstract][Full Text] [Related]  

  • 72. MCL1 inhibition enhances the therapeutic effect of MEK inhibitors in KRAS-mutant lung adenocarcinoma cells.
    Tada M; Sumi T; Tanaka Y; Hirai S; Yamaguchi M; Miyajima M; Niki T; Takahashi H; Watanabe A; Sakuma Y
    Lung Cancer; 2019 Jul; 133():88-95. PubMed ID: 31200834
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Mcl-1 and Bcl-x
    Hockings C; Alsop AE; Fennell SC; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Differ; 2018 Mar; 25(4):721-734. PubMed ID: 29459767
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
    Li R; Cheng C; Balasis ME; Liu Y; Garner TP; Daniel KG; Li J; Qin Y; Gavathiotis E; Sebti SM
    Eur J Med Chem; 2015 Jan; 90():315-331. PubMed ID: 25437618
    [TBL] [Abstract][Full Text] [Related]  

  • 75. MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma.
    Fu D; Pfannenstiel L; Demelash A; Phoon YP; Mayell C; Cabrera C; Liu C; Zhao J; Dermawan J; Patil D; DeVecchio J; Kalady M; Souers AJ; Phillips DC; Li X; Gastman B
    Cell Death Dis; 2022 Jan; 13(1):63. PubMed ID: 35042842
    [TBL] [Abstract][Full Text] [Related]  

  • 76. A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells.
    Yamanaka K; Rocchi P; Miyake H; Fazli L; Vessella B; Zangemeister-Wittke U; Gleave ME
    Mol Cancer Ther; 2005 Nov; 4(11):1689-98. PubMed ID: 16275990
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling.
    Peperzak V; Slinger E; Ter Burg J; Eldering E
    Cell Death Differ; 2017 Jan; 24(1):111-119. PubMed ID: 27689871
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition.
    Weeden CE; Ah-Cann C; Holik AZ; Pasquet J; Garnier JM; Merino D; Lessene G; Asselin-Labat ML
    Oncogene; 2018 Aug; 37(32):4475-4488. PubMed ID: 29743589
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
    Hayward RL; Macpherson JS; Cummings J; Monia BP; Smyth JF; Jodrell DI
    Clin Cancer Res; 2003 Jul; 9(7):2856-65. PubMed ID: 12855666
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer.
    Queralt B; Cuyàs E; Bosch-Barrera J; Massaguer A; de Llorens R; Martin-Castillo B; Brunet J; Salazar R; Menendez JA
    Oncotarget; 2016 Dec; 7(50):82185-82199. PubMed ID: 27636997
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.