BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 36624186)

  • 1. PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia.
    Xu X; Zhang W; Xuan L; Yu Y; Zheng W; Tao F; Nemechek J; He C; Ma W; Han X; Xie S; Zhao M; Wang J; Qu Y; Liu Q; Perry JM; Jiang L; Zhao M
    Nat Cell Biol; 2023 Jan; 25(1):170-182. PubMed ID: 36624186
    [TBL] [Abstract][Full Text] [Related]  

  • 2. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.
    Etchin J; Sanda T; Mansour MR; Kentsis A; Montero J; Le BT; Christie AL; McCauley D; Rodig SJ; Kauffman M; Shacham S; Stone R; Letai A; Kung AL; Thomas Look A
    Br J Haematol; 2013 Apr; 161(1):117-27. PubMed ID: 23373539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML.
    Li Z; Wang F; Tian X; Long J; Ling B; Zhang W; Xu J; Liang A
    J Exp Clin Cancer Res; 2021 Jun; 40(1):210. PubMed ID: 34167558
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
    Zhang J; Ding L; Holmfeldt L; Wu G; Heatley SL; Payne-Turner D; Easton J; Chen X; Wang J; Rusch M; Lu C; Chen SC; Wei L; Collins-Underwood JR; Ma J; Roberts KG; Pounds SB; Ulyanov A; Becksfort J; Gupta P; Huether R; Kriwacki RW; Parker M; McGoldrick DJ; Zhao D; Alford D; Espy S; Bobba KC; Song G; Pei D; Cheng C; Roberts S; Barbato MI; Campana D; Coustan-Smith E; Shurtleff SA; Raimondi SC; Kleppe M; Cools J; Shimano KA; Hermiston ML; Doulatov S; Eppert K; Laurenti E; Notta F; Dick JE; Basso G; Hunger SP; Loh ML; Devidas M; Wood B; Winter S; Dunsmore KP; Fulton RS; Fulton LL; Hong X; Harris CC; Dooling DJ; Ochoa K; Johnson KJ; Obenauer JC; Evans WE; Pui CH; Naeve CW; Ley TJ; Mardis ER; Wilson RK; Downing JR; Mullighan CG
    Nature; 2012 Jan; 481(7380):157-63. PubMed ID: 22237106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia.
    Gao J; Van Meter M; Hernandez Lopez S; Chen G; Huang Y; Ren S; Zhao Q; Rojas J; Gurer C; Thurston G; Kuhnert F
    Dis Model Mech; 2019 Sep; 12(9):. PubMed ID: 31399482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of FGF2/FGFR2 partially overcomes bone marrow mesenchymal stromal cells mediated progression of T-cell acute lymphoblastic leukaemia.
    Tian C; Li Y; Wang L; Si J; Zheng Y; Kang J; Wang Y; You MJ; Zheng G
    Cell Death Dis; 2022 Nov; 13(11):922. PubMed ID: 36333298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation.
    Kong Y; Zhang J; Claxton DF; Ehmann WC; Rybka WB; Zhu L; Zeng H; Schell TD; Zheng H
    Blood Cancer J; 2015 Jul; 5(7):e330. PubMed ID: 26230954
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion.
    Paczulla AM; Rothfelder K; Raffel S; Konantz M; Steinbacher J; Wang H; Tandler C; Mbarga M; Schaefer T; Falcone M; Nievergall E; Dörfel D; Hanns P; Passweg JR; Lutz C; Schwaller J; Zeiser R; Blazar BR; Caligiuri MA; Dirnhofer S; Lundberg P; Kanz L; Quintanilla-Martinez L; Steinle A; Trumpp A; Salih HR; Lengerke C
    Nature; 2019 Aug; 572(7768):254-259. PubMed ID: 31316209
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia.
    Fujita S; Honma D; Adachi N; Araki K; Takamatsu E; Katsumoto T; Yamagata K; Akashi K; Aoyama K; Iwama A; Kitabayashi I
    Leukemia; 2018 Apr; 32(4):855-864. PubMed ID: 28951561
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy.
    Hu Q; Sun W; Wang J; Ruan H; Zhang X; Ye Y; Shen S; Wang C; Lu W; Cheng K; Dotti G; Zeidner JF; Wang J; Gu Z
    Nat Biomed Eng; 2018 Nov; 2(11):831-840. PubMed ID: 31015615
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Notch1 and IL-7 receptor signalling in early T-cell development and leukaemia.
    González-García S; García-Peydró M; Alcain J; Toribio ML
    Curr Top Microbiol Immunol; 2012; 360():47-73. PubMed ID: 22695916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia.
    Chen L; Fan X; Zhu J; Chen X; Liu Y; Zhou H
    RNA Biol; 2020 Jun; 17(6):784-793. PubMed ID: 32174258
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PD-1 blockade potentially enhances adoptive cytotoxic T cell potency in a human acute myeloid leukaemia animal model.
    Deng R; Fan FY; Yi H; Liu F; He GC; Sun HP; Su Y
    Hematology; 2018 Dec; 23(10):740-746. PubMed ID: 29962321
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased expression of immune checkpoint programmed cell death protein-1 (PD-1) on T cell subsets of bone marrow aspirates in patients with B-Lymphoblastic leukemia, especially in relapse and at diagnosis.
    Park SH; You E; Park CJ; Cho YU; Jang S; Im HJ; Seo JJ; Park HS; Lee JH
    Cytometry B Clin Cytom; 2020 Jul; 98(4):336-347. PubMed ID: 32268011
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
    Coustan-Smith E; Mullighan CG; Onciu M; Behm FG; Raimondi SC; Pei D; Cheng C; Su X; Rubnitz JE; Basso G; Biondi A; Pui CH; Downing JR; Campana D
    Lancet Oncol; 2009 Feb; 10(2):147-56. PubMed ID: 19147408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Programmed Cell Death-1: Programmed Cell Death-Ligand 1 Interaction Protects Human Cardiomyocytes Against T-Cell Mediated Inflammation and Apoptosis Response In Vitro.
    Tay WT; Fang YH; Beh ST; Liu YW; Hsu LW; Yen CJ; Liu PY
    Int J Mol Sci; 2020 Mar; 21(7):. PubMed ID: 32244307
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
    Agnusdei V; Minuzzo S; Frasson C; Grassi A; Axelrod F; Satyal S; Gurney A; Hoey T; Seganfreddo E; Basso G; Valtorta S; Moresco RM; Amadori A; Indraccolo S
    Leukemia; 2014 Feb; 28(2):278-88. PubMed ID: 23774673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia.
    Zhong M; Gao R; Zhao R; Huang Y; Chen C; Li K; Yu X; Nie D; Chen Z; Liu X; Liu Z; Chen S; Lu Y; Yu Z; Wang L; Li P; Zeng C; Li Y
    Cell Death Dis; 2022 Aug; 13(8):671. PubMed ID: 35918330
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation.
    Guo W; Lasky JL; Chang CJ; Mosessian S; Lewis X; Xiao Y; Yeh JE; Chen JY; Iruela-Arispe ML; Varella-Garcia M; Wu H
    Nature; 2008 May; 453(7194):529-33. PubMed ID: 18463637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype.
    Fernandes MT; Ghezzo MN; Silveira AB; Kalathur RK; Póvoa V; Ribeiro AR; Brandalise SR; Dejardin E; Alves NL; Ghysdael J; Barata JT; Yunes JA; dos Santos NR
    Br J Haematol; 2015 Dec; 171(5):736-51. PubMed ID: 26456771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.