BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 36625768)

  • 1. Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.
    Němec V; Khirsariya P; Janovská P; Moyano PM; Maier L; Procházková P; Kebková P; Gybel' T; Berger BT; Chaikuad A; Reinecke M; Kuster B; Knapp S; Bryja V; Paruch K
    Angew Chem Int Ed Engl; 2023 Mar; 62(11):e202217532. PubMed ID: 36625768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors.
    Hua Z; Huang X; Bregman H; Chakka N; DiMauro EF; Doherty EM; Goldstein J; Gunaydin H; Huang H; Mercede S; Newcomb J; Patel VF; Turci SM; Yan J; Wilson C; Martin MW
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5392-5. PubMed ID: 22877629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting Casein Kinase 1 (CK1) in Hematological Cancers.
    Janovská P; Normant E; Miskin H; Bryja V
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33261128
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
    Halekotte J; Witt L; Ianes C; Krüger M; Bührmann M; Rauh D; Pichlo C; Brunstein E; Luxenburger A; Baumann U; Knippschild U; Bischof J; Peifer C
    Molecules; 2017 Mar; 22(4):. PubMed ID: 28338621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Achieving effective and selective CK1 inhibitors through structure modification.
    Du C; Yang H; Feng F; Liu W; Chen Y; Sun H
    Future Med Chem; 2021 Mar; 13(5):505-528. PubMed ID: 33438471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent Advances in the Development of Casein Kinase 1 Inhibitors.
    Li SS; Dong YH; Liu ZP
    Curr Med Chem; 2021; 28(8):1585-1604. PubMed ID: 32660395
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Casein Kinase 1δ Inhibitors as Promising Therapeutic Agents for Neurodegenerative Disorders.
    Catarzi D; Varano F; Vigiani E; Lambertucci C; Spinaci A; Volpini R; Colotta V
    Curr Med Chem; 2022; 29(27):4698-4737. PubMed ID: 35232339
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.
    García-Reyes B; Witt L; Jansen B; Karasu E; Gehring T; Leban J; Henne-Bruns D; Pichlo C; Brunstein E; Baumann U; Wesseler F; Rathmer B; Schade D; Peifer C; Knippschild U
    J Med Chem; 2018 May; 61(9):4087-4102. PubMed ID: 29630366
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.
    Fulcher LJ; Bozatzi P; Tachie-Menson T; Wu KZL; Cummins TD; Bufton JC; Pinkas DM; Dunbar K; Shrestha S; Wood NT; Weidlich S; Macartney TJ; Varghese J; Gourlay R; Campbell DG; Dingwell KS; Smith JC; Bullock AN; Sapkota GP
    Sci Signal; 2018 May; 11(531):. PubMed ID: 29789297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression.
    Sinnberg T; Wang J; Sauer B; Schittek B
    BMC Cancer; 2016 Aug; 16():594. PubMed ID: 27488834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ.
    Choi JY; Noguchi Y; Alburger JM; Bayle S; Chung E; Grant W; Chaikuad A; Knapp S; Duckett DR; Roush WR
    J Med Chem; 2023 Jun; 66(11):7162-7178. PubMed ID: 37204207
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
    Oumata N; Bettayeb K; Ferandin Y; Demange L; Lopez-Giral A; Goddard ML; Myrianthopoulos V; Mikros E; Flajolet M; Greengard P; Meijer L; Galons H
    J Med Chem; 2008 Sep; 51(17):5229-42. PubMed ID: 18698753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.
    Yang LL; Li GB; Yan HX; Sun QZ; Ma S; Ji P; Wang ZR; Feng S; Zou J; Yang SY
    Eur J Med Chem; 2012 Oct; 56():30-8. PubMed ID: 22944772
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Zebrafish as model system for the biological characterization of CK1 inhibitors.
    Meier L; Gahr BM; Roth A; Gihring A; Kirschner S; Woitaske-Proske C; Baier J; Peifer C; Just S; Knippschild U
    Front Pharmacol; 2023; 14():1245246. PubMed ID: 37753113
    [No Abstract]   [Full Text] [Related]  

  • 15. Inhibitors of casein kinase 1 block the growth of Leishmania major promastigotes in vitro.
    Allocco JJ; Donald R; Zhong T; Lee A; Tang YS; Hendrickson RC; Liberator P; Nare B
    Int J Parasitol; 2006 Oct; 36(12):1249-59. PubMed ID: 16890941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development.
    Knippschild U; Wolff S; Giamas G; Brockschmidt C; Wittau M; Würl PU; Eismann T; Stöter M
    Onkologie; 2005 Oct; 28(10):508-14. PubMed ID: 16186692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity.
    Fulcher LJ; Sapkota GP
    Biochem J; 2020 Dec; 477(23):4603-4621. PubMed ID: 33306089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
    Peifer C; Abadleh M; Bischof J; Hauser D; Schattel V; Hirner H; Knippschild U; Laufer S
    J Med Chem; 2009 Dec; 52(23):7618-30. PubMed ID: 19591487
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors.
    Wager TT; Galatsis P; Chandrasekaran RY; Butler TW; Li J; Zhang L; Mente S; Subramanyam C; Liu S; Doran AC; Chang C; Fisher K; Grimwood S; Hedde JR; Marconi M; Schildknegt K
    ACS Chem Neurosci; 2017 Sep; 8(9):1995-2004. PubMed ID: 28609096
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CK1 in Developmental Signaling: Hedgehog and Wnt.
    Jiang J
    Curr Top Dev Biol; 2017; 123():303-329. PubMed ID: 28236970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.