BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 36626555)

  • 1. Evolution of nanobodies specific for BCL11A.
    Yin M; Izadi M; Tenglin K; Viennet T; Zhai L; Zheng G; Arthanari H; Dassama LMK; Orkin SH
    Proc Natl Acad Sci U S A; 2023 Jan; 120(3):e2218959120. PubMed ID: 36626555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
    Xu J; Bauer DE; Kerenyi MA; Vo TD; Hou S; Hsu YJ; Yao H; Trowbridge JJ; Mandel G; Orkin SH
    Proc Natl Acad Sci U S A; 2013 Apr; 110(16):6518-23. PubMed ID: 23576758
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies.
    Liu B; Brendel C; Vinjamur DS; Zhou Y; Harris C; McGuinness M; Manis JP; Bauer DE; Xu H; Williams DA
    Mol Ther; 2022 Aug; 30(8):2693-2708. PubMed ID: 35526095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment.
    Funnell AP; Prontera P; Ottaviani V; Piccione M; Giambona A; Maggio A; Ciaffoni F; Stehling-Sun S; Marra M; Masiello F; Varricchio L; Stamatoyannopoulos JA; Migliaccio AR; Papayannopoulou T
    Blood; 2015 Jul; 126(1):89-93. PubMed ID: 26019277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells.
    Mehta S; Buyanbat A; Kai Y; Karayel O; Goldman SR; Seruggia D; Zhang K; Fujiwara Y; Donovan KA; Zhu Q; Yang H; Nabet B; Gray NS; Mann M; Fischer ES; Adelman K; Orkin SH
    Cell Chem Biol; 2022 Aug; 29(8):1273-1287.e8. PubMed ID: 35839780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus.
    Jawaid K; Wahlberg K; Thein SL; Best S
    Blood Cells Mol Dis; 2010 Aug; 45(2):140-6. PubMed ID: 20542454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
    Masuda T; Wang X; Maeda M; Canver MC; Sher F; Funnell AP; Fisher C; Suciu M; Martyn GE; Norton LJ; Zhu C; Kurita R; Nakamura Y; Xu J; Higgs DR; Crossley M; Bauer DE; Orkin SH; Kharchenko PV; Maeda T
    Science; 2016 Jan; 351(6270):285-9. PubMed ID: 26816381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Strict in vivo specificity of the
    Smith EC; Luc S; Croney DM; Woodworth MB; Greig LC; Fujiwara Y; Nguyen M; Sher F; Macklis JD; Bauer DE; Orkin SH
    Blood; 2016 Nov; 128(19):2338-2342. PubMed ID: 27707736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional silencing of fetal hemoglobin by BCL11A.
    Sankaran VG; Xu J; Orkin SH
    Ann N Y Acad Sci; 2010 Aug; 1202():64-8. PubMed ID: 20712774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences.
    Finotti A; Gasparello J; Zuccato C; Cosenza LC; Fabbri E; Bianchi N; Gambari R
    Genes (Basel); 2023 Oct; 14(10):. PubMed ID: 37895276
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency.
    Wessels MW; Cnossen MH; van Dijk TB; Gillemans N; Schmidt KLJ; van Lom K; Vinjamur DS; Coyne S; Kurita R; Nakamura Y; de Man SA; Pfundt R; Azmani Z; Brouwer RWW; Bauer DE; van den Hout MCGN; van IJcken WFJ; Philipsen S
    Blood Adv; 2021 May; 5(9):2339-2349. PubMed ID: 33938942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
    Bauer DE; Kamran SC; Lessard S; Xu J; Fujiwara Y; Lin C; Shao Z; Canver MC; Smith EC; Pinello L; Sabo PJ; Vierstra J; Voit RA; Yuan GC; Porteus MH; Stamatoyannopoulos JA; Lettre G; Orkin SH
    Science; 2013 Oct; 342(6155):253-7. PubMed ID: 24115442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA-92a-3p-mediated inhibition of BCL11A upregulates γ-globin expression and inhibits oxidative stress and apoptosis in erythroid precursor cells.
    Li H; Lin R; Li H; Ou R; Wang K; Lin J; Li C
    Hematology; 2022 Dec; 27(1):1152-1162. PubMed ID: 36178486
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.
    Basak A; Hancarova M; Ulirsch JC; Balci TB; Trkova M; Pelisek M; Vlckova M; Muzikova K; Cermak J; Trka J; Dyment DA; Orkin SH; Daly MJ; Sedlacek Z; Sankaran VG
    J Clin Invest; 2015 Jun; 125(6):2363-8. PubMed ID: 25938782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.
    Huang P; Peslak SA; Ren R; Khandros E; Qin K; Keller CA; Giardine B; Bell HW; Lan X; Sharma M; Horton JR; Abdulmalik O; Chou ST; Shi J; Crossley M; Hardison RC; Cheng X; Blobel GA
    Nat Genet; 2022 Sep; 54(9):1417-1426. PubMed ID: 35941187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
    Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
    Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Estimation of the difference in HbF expression due to loss of the 5' δ-globin BCL11A binding region.
    Ghedira ES; Lecerf L; Faubert E; Costes B; Moradkhani K; Bachir D; Galactéros F; Pissard S
    Haematologica; 2013 Feb; 98(2):305-8. PubMed ID: 22801970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Cell-Permeant Nanobody-Based Degrader That Induces Fetal Hemoglobin.
    Shen F; Zheng G; Setegne M; Tenglin K; Izadi M; Xie H; Zhai L; Orkin SH; Dassama LMK
    ACS Cent Sci; 2022 Dec; 8(12):1695-1703. PubMed ID: 36589886
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.