140 related articles for article (PubMed ID: 36629272)
1. Potentiation of Lipotoxicity in Human EndoC-βH1 β-Cells by Glucose is Dependent on the Structure of Free Fatty Acids.
von Hanstein AS; Tsikas D; Lenzen S; Jörns A; Plötz T
Mol Nutr Food Res; 2023 Mar; 67(5):e2200582. PubMed ID: 36629272
[TBL] [Abstract][Full Text] [Related]
2. Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells.
Plötz T; von Hanstein AS; Krümmel B; Laporte A; Mehmeti I; Lenzen S
Biochim Biophys Acta Mol Basis Dis; 2019 Nov; 1865(11):165525. PubMed ID: 31398470
[TBL] [Abstract][Full Text] [Related]
3. Toxicity of fatty acid profiles of popular edible oils in human EndoC-βH1 beta-cells.
von Hanstein AS; Lenzen S; Plötz T
Nutr Diabetes; 2020 Jan; 10(1):5. PubMed ID: 32066652
[TBL] [Abstract][Full Text] [Related]
4. The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells.
Plötz T; Krümmel B; Laporte A; Pingitore A; Persaud SJ; Jörns A; Elsner M; Mehmeti I; Lenzen S
Nutr Diabetes; 2017 Dec; 7(12):305. PubMed ID: 29269872
[TBL] [Abstract][Full Text] [Related]
5. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Oshima M; Pechberty S; Bellini L; Göpel SO; Campana M; Rouch C; Dairou J; Cosentino C; Fantuzzi F; Toivonen S; Marchetti P; Magnan C; Cnop M; Le Stunff H; Scharfmann R
Diabetologia; 2020 Feb; 63(2):395-409. PubMed ID: 31796987
[TBL] [Abstract][Full Text] [Related]
6. Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity.
Tang Y; Plötz T; Gräler MH; Gurgul-Convey E
Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639233
[TBL] [Abstract][Full Text] [Related]
7. The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
Tsonkova VG; Sand FW; Wolf XA; Grunnet LG; Kirstine Ringgaard A; Ingvorsen C; Winkel L; Kalisz M; Dalgaard K; Bruun C; Fels JJ; Helgstrand C; Hastrup S; Öberg FK; Vernet E; Sandrini MPB; Shaw AC; Jessen C; Grønborg M; Hald J; Willenbrock H; Madsen D; Wernersson R; Hansson L; Jensen JN; Plesner A; Alanentalo T; Petersen MBK; Grapin-Botton A; Honoré C; Ahnfelt-Rønne J; Hecksher-Sørensen J; Ravassard P; Madsen OD; Rescan C; Frogne T
Mol Metab; 2018 Feb; 8():144-157. PubMed ID: 29307512
[TBL] [Abstract][Full Text] [Related]
8. Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes.
Lytrivi M; Castell AL; Poitout V; Cnop M
J Mol Biol; 2020 Mar; 432(5):1514-1534. PubMed ID: 31628942
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of lipotoxicity-induced dysfunction and death of human pancreatic beta cells under obesity and type 2 diabetes conditions.
Plötz T; Lenzen S
Obes Rev; 2024 May; 25(5):e13703. PubMed ID: 38327101
[TBL] [Abstract][Full Text] [Related]
10. Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells.
Iwai T; Kume S; Chin-Kanasaki M; Kuwagata S; Araki H; Takeda N; Sugaya T; Uzu T; Maegawa H; Araki SI
Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27834856
[TBL] [Abstract][Full Text] [Related]
11. Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells.
Thomas P; Arden C; Corcoran J; Hacker C; Welters HJ; Morgan NG
Nutr Diabetes; 2022 Apr; 12(1):22. PubMed ID: 35443738
[TBL] [Abstract][Full Text] [Related]
12. EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium.
Krizhanovskii C; Kristinsson H; Elksnis A; Wang X; Gavali H; Bergsten P; Scharfmann R; Welsh N
Islets; 2017 May; 9(3):e1296995. PubMed ID: 28277987
[TBL] [Abstract][Full Text] [Related]
13. Physiological characterization of the human EndoC-βH1 β-cell line.
Gurgul-Convey E; Kaminski MT; Lenzen S
Biochem Biophys Res Commun; 2015 Aug; 464(1):13-9. PubMed ID: 26028562
[TBL] [Abstract][Full Text] [Related]
14. Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines.
Gurgul-Convey E; Mehmeti I; Plötz T; Jörns A; Lenzen S
Diabetologia; 2016 Oct; 59(10):2125-33. PubMed ID: 27460666
[TBL] [Abstract][Full Text] [Related]
15. Differential effects of saturated and unsaturated free fatty acids on ferroptosis in rat β-cells.
Krümmel B; von Hanstein AS; Plötz T; Lenzen S; Mehmeti I
J Nutr Biochem; 2022 Aug; 106():109013. PubMed ID: 35447320
[TBL] [Abstract][Full Text] [Related]
16. Sterol regulatory element-binding protein-1c knockdown protected INS-1E cells from lipotoxicity.
Li J; Liu X; Ran X; Chen J; Li X; Wu W; Huang H; Huang H; Long Y; Liang J; Cheng J; Tian H
Diabetes Obes Metab; 2010 Jan; 12(1):35-46. PubMed ID: 19758361
[TBL] [Abstract][Full Text] [Related]
17. Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells.
Scaglia N; Igal RA
J Biol Chem; 2005 Jul; 280(27):25339-49. PubMed ID: 15851470
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor.
Doliba NM; Liu Q; Li C; Chen P; Liu C; Naji A; Matschinsky FM
Mol Metab; 2017 Oct; 6(10):1240-1253. PubMed ID: 29031723
[TBL] [Abstract][Full Text] [Related]
19. ER stress attenuation by Aloe-derived polysaccharides in the protection of pancreatic β-cells from free fatty acid-induced lipotoxicity.
Kim K; Chung MH; Park S; Cha J; Baek JH; Lee SY; Choi SY
Biochem Biophys Res Commun; 2018 Jun; 500(3):797-803. PubMed ID: 29684344
[TBL] [Abstract][Full Text] [Related]
20. Glucolipotoxicity, β-Cells, and Diabetes: The Emperor Has No Clothes.
Weir GC
Diabetes; 2020 Mar; 69(3):273-278. PubMed ID: 31519699
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
