BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 36629428)

  • 1. Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells.
    Zhang G; Tang Z; Fan S; Li C; Li Y; Liu W; Long X; Zhang W; Zhang Y; Li Z; Wang Z; Chen D; Ouyang G
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2163393. PubMed ID: 36629428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers.
    El-Sharief AMS; Ammar YA; Belal A; El-Sharief MAMS; Mohamed YA; Mehany ABM; Elhag Ali GAM; Ragab A
    Bioorg Chem; 2019 Apr; 85():399-412. PubMed ID: 30665034
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR.
    Wassel MMS; Ammar YA; Elhag Ali GAM; Belal A; Mehany ABM; Ragab A
    Bioorg Chem; 2021 May; 110():104794. PubMed ID: 33735711
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors.
    Sever B; Altıntop MD; Özdemir A; Akalın Çiftçi G; Ellakwa DE; Tateishi H; Radwan MO; Ibrahim MAA; Otsuka M; Fujita M; Ciftci HI; Ali TFS
    Molecules; 2020 Nov; 25(21):. PubMed ID: 33171861
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study.
    Saruengkhanphasit R; Butkinaree C; Ornnork N; Lirdprapamongkol K; Niwetmarin W; Svasti J; Ruchirawat S; Eurtivong C
    Bioorg Chem; 2021 May; 110():104795. PubMed ID: 33730670
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents.
    Li Z; Luo M; Cai B; Haroon-Ur-Rashid ; Huang M; Jiang J; Wang L; Wu L
    Eur J Med Chem; 2018 Sep; 157():665-682. PubMed ID: 30125725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis and Antitumor Activity of 1
    Wang C; Zhu M; Long X; Wang Q; Wang Z; Ouyang G
    Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37240028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3β (GSK-3β) phosphorylation inhibitors.
    Zhao P; Li Y; Gao G; Wang S; Yan Y; Zhan X; Liu Z; Mao Z; Chen S; Wang L
    Eur J Med Chem; 2014 Oct; 86():165-74. PubMed ID: 25151579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
    Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights.
    Al-Warhi T; El Kerdawy AM; Said MA; Albohy A; Elsayed ZM; Aljaeed N; Elkaeed EB; Eldehna WM; Abdel-Aziz HA; Abdelmoaz MA
    Drug Des Devel Ther; 2022; 16():1457-1471. PubMed ID: 35607598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, and Cytotoxic Activities of Indole and Indazole-Based Stilbenes.
    Ma Z; Zhang W; Han X; Chen Y; Li G
    Chem Biodivers; 2023 May; 20(5):e202300368. PubMed ID: 36996024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAF
    Al-Wahaibi LH; Gouda AM; Abou-Ghadir OF; Salem OIA; Ali AT; Farghaly HS; Abdelrahman MH; Trembleau L; Abdu-Allah HHM; Youssif BGM
    Bioorg Chem; 2020 Nov; 104():104260. PubMed ID: 32920363
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights.
    Sabt A; Eldehna WM; Al-Warhi T; Alotaibi OJ; Elaasser MM; Suliman H; Abdel-Aziz HA
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1616-1630. PubMed ID: 32781872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel 4-arylaminoquinazolines bearing
    Zhang Y; Chen L; Li X; Gao L; Hao Y; Li B; Yan Y
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1668-1677. PubMed ID: 31530043
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel isoxazoline-linked 1,3,4-thiadiazole hybrids as anticancer agents: Design, synthesis, biological evaluation, molecular docking, and molecular dynamics simulation.
    Oubella A; Byadi S; Bimoussa A; Fawzi M; Auhmani A; Podlipnik C; Morjani H; Riahi A; Robert A; Itto MYA
    Arch Pharm (Weinheim); 2022 Sep; 355(9):e2200066. PubMed ID: 35594031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and characterisation of celastrol derivatives as potential anticancer agents.
    Zhang HJ; Zhang GR; Piao HR; Quan ZS
    J Enzyme Inhib Med Chem; 2017 Dec; 33(1):190-198. PubMed ID: 29231066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors.
    El-Sayed NF; El-Hussieny M; Ewies EF; El Shehry MF; Awad HM; Fouad MA
    Drug Dev Res; 2022 Apr; 83(2):485-500. PubMed ID: 34523738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and Cytotoxic Properties of New Substituted Glycosides-Indole Conjugates as Apoptosis Inducers in Cancer Cells.
    Srour AM; El-Bayaa MN; Omran MM; Sharaky MM; El-Sayed WA
    Anticancer Agents Med Chem; 2021; 21(10):1323-1333. PubMed ID: 32990545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.