BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 36631248)

  • 1. Preclinical mouse model of a misfolded PNLIP variant develops chronic pancreatitis.
    Zhu G; Wilhelm SJ; George LG; Cassidy BM; Zino S; Luke CJ; Hanna M; Stone S; Phan N; Matiwala N; Ballentine SJ; Lowe ME; Xiao X
    Gut; 2023 Jul; 72(7):1340-1354. PubMed ID: 36631248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding.
    Szabó A; Xiao X; Haughney M; Spector A; Sahin-Tóth M; Lowe ME
    Biochim Biophys Acta; 2015 Jul; 1852(7):1372-9. PubMed ID: 25862608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress.
    Toldi V; Kassay N; Szabó A
    Pancreatology; 2021 Oct; 21(7):1317-1325. PubMed ID: 34373204
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human
    Hegyi E; Sahin-Tóth M
    Gut; 2019 Feb; 68(2):301-312. PubMed ID: 30045879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Misfolding-induced chronic pancreatitis in CPA1 N256K mutant mice is unaffected by global deletion of Ddit3/Chop.
    Németh BC; Demcsák A; Geisz A; Sahin-Tóth M
    Sci Rep; 2022 Apr; 12(1):6357. PubMed ID: 35428786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis.
    Cooley MM; Thomas DDH; Deans K; Peng Y; Lugea A; Pandol SJ; Puglielli L; Groblewski GE
    Cell Mol Gastroenterol Hepatol; 2021; 11(3):725-738. PubMed ID: 33080365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum stress is chronically activated in chronic pancreatitis.
    Sah RP; Garg SK; Dixit AK; Dudeja V; Dawra RK; Saluja AK
    J Biol Chem; 2014 Oct; 289(40):27551-61. PubMed ID: 25077966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells.
    Lugea A; Gerloff A; Su HY; Xu Z; Go A; Hu C; French SW; Wilson JS; Apte MV; Waldron RT; Pandol SJ
    Gastroenterology; 2017 Dec; 153(6):1674-1686. PubMed ID: 28847752
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of novel PNLIP variants in congenital pancreatic lipase deficiency.
    Lin J; Matiwala N; Curry GE; Wilhelm SJ; Cassidy BM; Lowe ME; Xiao X
    Pancreatology; 2023 Dec; 23(8):1036-1040. PubMed ID: 37926600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploring the enigmatic association between PNLIP variants and risk of chronic pancreatitis in a large Chinese cohort.
    Cassidy BM; Jiang F; Lin J; Chen JM; Curry GE; Ma GX; Wilhelm SJ; Deng SJ; Zhu G; Liao Z; Lowe ME; Xiao XK; Zou WB
    Pancreatology; 2024 Mar; ():. PubMed ID: 38485544
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice.
    Wang S; Chao X; Jiang X; Wang T; Rodriguez Y; Yang L; Pacher P; Ni HM; Ding WX
    Autophagy; 2022 Jul; 18(7):1572-1582. PubMed ID: 34709991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of protease-sensitive but not misfolding PNLIP variants in familial and hereditary pancreatitis.
    Masson E; Berthet S; Le Gac G; Le Rhun M; Ka C; Autret S; Gourlaouen I; ; Cooper DN; Férec C; Rebours V; Chen JM
    Pancreatology; 2023 Aug; 23(5):507-511. PubMed ID: 37270400
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells.
    Szmola R; Sahin-Tóth M
    Gut; 2010 Mar; 59(3):365-72. PubMed ID: 19951900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice.
    Fjeld K; Gravdal A; Brekke RS; Alam J; Wilhelm SJ; El Jellas K; Pettersen HN; Lin J; Solheim MH; Steine SJ; Johansson BB; Njølstad PR; Verbeke CS; Xiao X; Lowe ME; Molven A
    Pancreatology; 2022 Dec; 22(8):1099-1111. PubMed ID: 36379850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
    Diakopoulos KN; Lesina M; Wörmann S; Song L; Aichler M; Schild L; Artati A; Römisch-Margl W; Wartmann T; Fischer R; Kabiri Y; Zischka H; Halangk W; Demir IE; Pilsak C; Walch A; Mantzoros CS; Steiner JM; Erkan M; Schmid RM; Witt H; Adamski J; Algül H
    Gastroenterology; 2015 Mar; 148(3):626-638.e17. PubMed ID: 25497209
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Undercarboxylated osteocalcin downregulates pancreatic lipase expression in an ATF4-dependent manner in pancreatic acinar cells.
    Park D; Gu H; Baek JH; Baek K
    Bone; 2019 Oct; 127():220-227. PubMed ID: 31216497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.
    Seyhun E; Malo A; Schäfer C; Moskaluk CA; Hoffmann RT; Göke B; Kubisch CH
    Am J Physiol Gastrointest Liver Physiol; 2011 Nov; 301(5):G773-82. PubMed ID: 21778463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.
    Phillipson-Weiner L; Mirek ET; Wang Y; McAuliffe WG; Wek RC; Anthony TG
    Am J Physiol Gastrointest Liver Physiol; 2016 Jun; 310(11):G1061-70. PubMed ID: 26968207
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis.
    Xiao X; Jones G; Sevilla WA; Stolz DB; Magee KE; Haughney M; Mukherjee A; Wang Y; Lowe ME
    J Biol Chem; 2016 Oct; 291(44):23224-23236. PubMed ID: 27650499
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A rare PRSS1 p.S127C mutation is associated with chronic pancreatitis and causes misfolding-induced ER-stress.
    Thiel F; Reiser M; Weiss FU
    Pancreatology; 2022 Dec; 22(8):1112-1119. PubMed ID: 36369231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.