BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 36635564)

  • 1. Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
    Guo Y; Zhang H; Yan C; Shen B; Zhang Y; Guo X; Sun S; Yu F; Yan J; Liu R; Zhang Q; Zhang D; Liu H; Liu Y; Zhang Y; Li W; Qin J; Lv H; Wang Z; Yuan Y; Yang JF; Zhong YT; Gao S; Zhou B; Liu L; Kong D; Hao X; Hu J; Chen Q
    Nat Chem Biol; 2023 Apr; 19(4):468-477. PubMed ID: 36635564
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion.
    Cao YL; Meng S; Chen Y; Feng JX; Gu DD; Yu B; Li YJ; Yang JY; Liao S; Chan DC; Gao S
    Nature; 2017 Feb; 542(7641):372-376. PubMed ID: 28114303
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion.
    Yan L; Qi Y; Huang X; Yu C; Lan L; Guo X; Rao Z; Hu J; Lou Z
    Nat Struct Mol Biol; 2018 Mar; 25(3):233-243. PubMed ID: 29483649
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30.
    Yue W; Chen Z; Liu H; Yan C; Chen M; Feng D; Yan C; Wu H; Du L; Wang Y; Liu J; Huang X; Xia L; Liu L; Wang X; Jin H; Wang J; Song Z; Hao X; Chen Q
    Cell Res; 2014 Apr; 24(4):482-96. PubMed ID: 24513856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A dominant negative mitofusin causes mitochondrial perinuclear clusters because of aberrant tethering.
    Sloat SR; Hoppins S
    Life Sci Alliance; 2023 Jan; 6(1):. PubMed ID: 36229071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
    Li S; Han S; Zhang Q; Zhu Y; Zhang H; Wang J; Zhao Y; Zhao J; Su L; Li L; Zhou D; Ye C; Feng XH; Liang T; Zhao B
    Nat Commun; 2022 Jun; 13(1):3486. PubMed ID: 35710796
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The GDP-Bound State of Mitochondrial Mfn1 Induces Membrane Adhesion of Apposing Lipid Vesicles through a Cooperative Binding Mechanism.
    Tolosa-Díaz A; Almendro-Vedia VG; Natale P; López-Montero I
    Biomolecules; 2020 Jul; 10(7):. PubMed ID: 32708307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.
    Hall AR; Burke N; Dongworth RK; Kalkhoran SB; Dyson A; Vicencio JM; Dorn GW; Yellon DM; Hausenloy DJ
    Cell Death Dis; 2016 May; 7(5):e2238. PubMed ID: 27228353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of Mitofusin1 by Mahogunin Ring Finger-1 and the proteasome modulates mitochondrial fusion.
    Mukherjee R; Chakrabarti O
    Biochim Biophys Acta; 2016 Dec; 1863(12):3065-3083. PubMed ID: 27713096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion.
    Daste F; Sauvanet C; Bavdek A; Baye J; Pierre F; Le Borgne R; David C; Rojo M; Fuchs P; Tareste D
    EMBO Rep; 2018 Jun; 19(6):. PubMed ID: 29661855
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.
    Santel A; Frank S; Gaume B; Herrler M; Youle RJ; Fuller MT
    J Cell Sci; 2003 Jul; 116(Pt 13):2763-74. PubMed ID: 12759376
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of human mitofusin 1 provide insight into mitochondrial tethering.
    Qi Y; Yan L; Yu C; Guo X; Zhou X; Hu X; Huang X; Rao Z; Lou Z; Hu J
    J Cell Biol; 2016 Dec; 215(5):621-629. PubMed ID: 27920125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover.
    Amiott EA; Cohen MM; Saint-Georges Y; Weissman AM; Shaw JM
    Mol Biol Cell; 2009 Dec; 20(23):5026-35. PubMed ID: 19812251
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity.
    Ishihara N; Eura Y; Mihara K
    J Cell Sci; 2004 Dec; 117(Pt 26):6535-46. PubMed ID: 15572413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion.
    Liu C; Sun Z; Wang M; Yang Z; Zhang W; Ren Y; Han X; Zhang B; Yao M; Nie S
    J Biochem Mol Toxicol; 2022 Sep; 36(9):e23127. PubMed ID: 35686354
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2.
    Sloat SR; Whitley BN; Engelhart EA; Hoppins S
    Mol Biol Cell; 2019 Aug; 30(17):2309-2319. PubMed ID: 31188717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequences flanking the transmembrane segments facilitate mitochondrial localization and membrane fusion by mitofusin.
    Huang X; Zhou X; Hu X; Joshi AS; Guo X; Zhu Y; Chen Q; Prinz WA; Hu J
    Proc Natl Acad Sci U S A; 2017 Nov; 114(46):E9863-E9872. PubMed ID: 29093165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch1 protects against myocardial ischaemia-reperfusion injury via regulating mitochondrial fusion and function.
    Dai SH; Wu QC; Zhu RR; Wan XM; Zhou XL
    J Cell Mol Med; 2020 Mar; 24(5):3183-3191. PubMed ID: 31975567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism.
    Miret-Casals L; Sebastián D; Brea J; Rico-Leo EM; Palacín M; Fernández-Salguero PM; Loza MI; Albericio F; Zorzano A
    Cell Chem Biol; 2018 Mar; 25(3):268-278.e4. PubMed ID: 29290623
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1.
    Mallat A; Uchiyama LF; Lewis SC; Fredenburg RA; Terada Y; Ji N; Nunnari J; Tseng CC
    Biochem Biophys Res Commun; 2018 May; 499(3):556-562. PubMed ID: 29601815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.