BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 36661300)

  • 1. RORγt inhibition ameliorates IL-23 driven experimental psoriatic arthritis by predominantly modulating γδ-T cells.
    Mortier C; Gracey E; Coudenys J; Manuello T; Decruy T; Maelegheer M; Stappers F; Gilis E; Gaublomme D; Van Hoorebeke L; Van Welden S; Ambler C; Hegen M; Symanowicz P; Steyn S; Berstein G; Elewaut D; Venken K
    Rheumatology (Oxford); 2023 Sep; 62(9):3169-3178. PubMed ID: 36661300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells.
    Cornelissen F; Mus AM; Asmawidjaja PS; van Hamburg JP; Tocker J; Lubberts E
    Arthritis Res Ther; 2009; 11(6):R194. PubMed ID: 20017902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.
    Xue X; Soroosh P; De Leon-Tabaldo A; Luna-Roman R; Sablad M; Rozenkrants N; Yu J; Castro G; Banie H; Fung-Leung WP; Santamaria-Babi L; Schlueter T; Albers M; Leonard K; Budelsky AL; Fourie AM
    Sci Rep; 2016 Dec; 6():37977. PubMed ID: 27905482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation.
    Ma L; Xue H; Qi R; Wang Y; Yuan L
    J Transl Med; 2018 Mar; 16(1):59. PubMed ID: 29523162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
    Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
    J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Interleukin-23-Mediated Inflammation with a Novel Small Molecule Inverse Agonist of ROR
    Gauld SB; Jacquet S; Gauvin D; Wallace C; Wang Y; McCarthy R; Goess C; Leys L; Huang S; Su Z; Edelmayer R; Wetter J; Salte K; McGaraughty SP; Argiriadi MA; Honore P; Luccarini JM; Bressac D; Desino K; Breinlinger E; Cusack K; Potin D; Kort ME; Masson PJ
    J Pharmacol Exp Ther; 2019 Oct; 371(1):208-218. PubMed ID: 31375639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile.
    Bautista-Herrera LA; De la Cruz-Mosso U; Román-Fernández IV; Parra-Rojas I; Soñanez-Organis JG; Hernández-Bello J; Morales-Zambrano RA; Villanueva-Quintero GD; Muñoz-Valle JF
    Int J Immunopathol Pharmacol; 2020; 34():2058738420907186. PubMed ID: 32138573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients.
    Venken K; Jacques P; Mortier C; Labadia ME; Decruy T; Coudenys J; Hoyt K; Wayne AL; Hughes R; Turner M; Van Gassen S; Martens L; Smith D; Harcken C; Wahle J; Wang CT; Verheugen E; Schryvers N; Varkas G; Cypers H; Wittoek R; Piette Y; Gyselbrecht L; Van Calenbergh S; Van den Bosch F; Saeys Y; Nabozny G; Elewaut D
    Nat Commun; 2019 Jan; 10(1):9. PubMed ID: 30602780
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice.
    Reinhardt A; Yevsa T; Worbs T; Lienenklaus S; Sandrock I; Oberdörfer L; Korn T; Weiss S; Förster R; Prinz I
    Arthritis Rheumatol; 2016 Oct; 68(10):2476-86. PubMed ID: 27111864
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17.
    Takaishi M; Ishizaki M; Suzuki K; Isobe T; Shimozato T; Sano S
    J Dermatol Sci; 2017 Jan; 85(1):12-19. PubMed ID: 27726924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CXCR3 antagonist NBI-74330 mitigates joint inflammation in Collagen-Induced arthritis model in DBA/1J mice.
    Ahmad SF; Nadeem A; Ansari MA; Bakheet SA; Alomar HA; Al-Mazroua HA; Ibrahim KE; Alshamrani AA; Al-Hamamah MA; Alfardan AS; Attia SM
    Int Immunopharmacol; 2023 May; 118():110099. PubMed ID: 37018975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses.
    Ecoeur F; Weiss J; Kaupmann K; Hintermann S; Orain D; Guntermann C
    Front Immunol; 2019; 10():577. PubMed ID: 30972071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
    Guendisch U; Weiss J; Ecoeur F; Riker JC; Kaupmann K; Kallen J; Hintermann S; Orain D; Dawson J; Billich A; Guntermann C
    PLoS One; 2017; 12(11):e0188391. PubMed ID: 29155882
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AT-rich-interactive domain-containing protein 5A functions as a negative regulator of retinoic acid receptor-related orphan nuclear receptor γt-induced Th17 cell differentiation.
    Saito Y; Kagami S; Sanayama Y; Ikeda K; Suto A; Kashiwakuma D; Furuta S; Iwamoto I; Nonaka K; Ohara O; Nakajima H
    Arthritis Rheumatol; 2014 May; 66(5):1185-94. PubMed ID: 24782182
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer.
    Punkenburg E; Vogler T; Büttner M; Amann K; Waldner M; Atreya R; Abendroth B; Mudter J; Merkel S; Gallmeier E; Rose-John S; Neurath MF; Hildner K
    Gut; 2016 Jul; 65(7):1139-50. PubMed ID: 25838550
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice.
    Pantelyushin S; Haak S; Ingold B; Kulig P; Heppner FL; Navarini AA; Becher B
    J Clin Invest; 2012 Jun; 122(6):2252-6. PubMed ID: 22546855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thiostrepton alleviates experimental colitis by promoting RORγt ubiquitination and modulating dysbiosis.
    Luo Y; Liu C; Luo Y; Zhang X; Li J; Hu C; Yang S
    Cell Mol Immunol; 2023 Nov; 20(11):1352-1366. PubMed ID: 37752225
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deficiency of IL-17A, but not the prototypical Th17 transcription factor RORγt, decreases murine spontaneous intestinal tumorigenesis.
    Shapiro M; Nandi B; Pai C; Samur MK; Pelluru D; Fulciniti M; Prabhala RH; Munshi NC; Gold JS
    Cancer Immunol Immunother; 2016 Jan; 65(1):13-24. PubMed ID: 26559812
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel benzenediamine derivative FC99 ameliorates zymosan-induced arthritis by inhibiting RORγt expression and Th17 cell differentiation.
    Ji J; Dou H; Li X; Song Y; Li X; Li E; Tan R; Hou Y
    Acta Biochim Biophys Sin (Shanghai); 2014 Oct; 46(10):829-36. PubMed ID: 25187413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RORγt protein modifications and IL-17-mediated inflammation.
    Kumar R; Theiss AL; Venuprasad K
    Trends Immunol; 2021 Nov; 42(11):1037-1050. PubMed ID: 34635393
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.