BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 36669486)

  • 1. Base editing screens map mutations affecting interferon-γ signaling in cancer.
    Coelho MA; Cooper S; Strauss ME; Karakoc E; Bhosle S; Gonçalves E; Picco G; Burgold T; Cattaneo CM; Veninga V; Consonni S; Dinçer C; Vieira SF; Gibson F; Barthorpe S; Hardy C; Rein J; Thomas M; Marioni J; Voest EE; Bassett A; Garnett MJ
    Cancer Cell; 2023 Feb; 41(2):288-303.e6. PubMed ID: 36669486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction.
    Huang C; Li G; Wu J; Liang J; Wang X
    Genome Biol; 2021 Mar; 22(1):80. PubMed ID: 33691754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation patterns in genes encoding interferon signaling and antigen presentation: A pan-cancer survey with implications for the use of immune checkpoint inhibitors.
    Budczies J; Bockmayr M; Klauschen F; Endris V; Fröhling S; Schirmacher P; Denkert C; Stenzinger A
    Genes Chromosomes Cancer; 2017 Aug; 56(8):651-659. PubMed ID: 28466543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction.
    Cornean A; Gierten J; Welz B; Mateo JL; Thumberger T; Wittbrodt J
    Elife; 2022 Apr; 11():. PubMed ID: 35373735
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-throughput functional evaluation of human cancer-associated mutations using base editors.
    Kim Y; Lee S; Cho S; Park J; Chae D; Park T; Minna JD; Kim HH
    Nat Biotechnol; 2022 Jun; 40(6):874-884. PubMed ID: 35411116
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrated CRISPR-Cas9 System-Mediated Knockout of IFN-γ and IFN-γ Receptor 1 in the Vero Cell Line Promotes Viral Susceptibility.
    Kim S; Nowakowska A; Kim YB; Shin HY
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35897807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells.
    Rath A; Mishra A; Ferreira VD; Hu C; Omerza G; Kelly K; Hesse A; Reddi HV; Grady JP; Heinen CD
    Hum Mutat; 2019 Nov; 40(11):2044-2056. PubMed ID: 31237724
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
    Freeman AJ; Vervoort SJ; Ramsbottom KM; Kelly MJ; Michie J; Pijpers L; Johnstone RW; Kearney CJ; Oliaro J
    Cell Rep; 2019 Sep; 28(11):2784-2794.e5. PubMed ID: 31509742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the cGAS-STING pathway combined with CRISPR-Cas9 gene editing triggering long-term immunotherapy.
    Lu Q; Chen R; Du S; Chen C; Pan Y; Luan X; Yang J; Zeng F; He B; Han X; Song Y
    Biomaterials; 2022 Dec; 291():121871. PubMed ID: 36323073
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The use of CRISPR/Cas9-based gene editing strategies to explore cancer gene function in mice.
    van der Weyden L; Jonkers J; Adams DJ
    Curr Opin Genet Dev; 2021 Feb; 66():57-62. PubMed ID: 33429291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Immunotherapy to get on point with base editing.
    Harbottle JA
    Drug Discov Today; 2021 Oct; 26(10):2350-2357. PubMed ID: 33857616
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells.
    Woznicki JA; Saini N; Flood P; Rajaram S; Lee CM; Stamou P; Skowyra A; Bustamante-Garrido M; Regazzoni K; Crawford N; McDade SS; Longley DB; Aza-Blanc P; Shanahan F; Zulquernain SA; McCarthy J; Melgar S; McRae BL; Nally K
    Cell Death Dis; 2021 Sep; 12(10):864. PubMed ID: 34556638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies.
    Cai B; Liu Y; Chong Y; Zhang H; Matsunaga A; Fang X; Pacholczyk R; Zhou G; Cowell JK; Hu T
    Mol Cancer; 2021 Dec; 20(1):165. PubMed ID: 34906138
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IFNγ signaling integrity in colorectal cancer immunity and immunotherapy.
    Du W; Frankel TL; Green M; Zou W
    Cell Mol Immunol; 2022 Jan; 19(1):23-32. PubMed ID: 34385592
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing.
    Sayed S; Sidorova OA; Hennig A; Augsburg M; Cortés Vesga CP; Abohawya M; Schmitt LT; Sürün D; Stange DE; Mircetic J; Buchholz F
    Cancer Res; 2022 Sep; 82(17):3002-3015. PubMed ID: 35802645
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [CRISPR/Cas-mediated DNA base editing technology and its application in biomedicine and agriculture].
    Yu C; Mo J; Zhao X; Li G; Zhang X
    Sheng Wu Gong Cheng Xue Bao; 2021 Sep; 37(9):3071-3087. PubMed ID: 34622618
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma.
    Kalbasi A; Tariveranmoshabad M; Hakimi K; Kremer S; Campbell KM; Funes JM; Vega-Crespo A; Parisi G; Champekar A; Nguyen C; Torrejon D; Shin D; Zaretsky JM; Damoiseaux RD; Speiser DE; Lopez-Casas PP; Quintero M; Ribas A
    Sci Transl Med; 2020 Oct; 12(565):. PubMed ID: 33055240
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Progression and application of CRISPR-Cas genomic editors.
    Yang L; Tang J; Ma X; Lin Y; Ma G; Shan M; Wang L; Yang Y
    Methods; 2021 Oct; 194():65-74. PubMed ID: 33774156
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Double Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in Yeast.
    Després PC; Dubé AK; Nielly-Thibault L; Yachie N; Landry CR
    G3 (Bethesda); 2018 Oct; 8(10):3163-3171. PubMed ID: 30097473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells.
    Walsh ZH; Shah P; Kothapalli N; Nikolenyi G; Shah SB; Leuzzi G; Mu M; Ho P; Abuzaid S; Brodtman ZD; Vasan N; AlQuraishi M; Milner JD; Ciccia A; Melms JC; Izar B
    bioRxiv; 2023 Dec; ():. PubMed ID: 38168306
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.