BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 36680944)

  • 1. The dual role of DNA repair protein MGMT in cancer prevention and treatment.
    Bai P; Fan T; Sun G; Wang X; Zhao L; Zhong R
    DNA Repair (Amst); 2023 Mar; 123():103449. PubMed ID: 36680944
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulating MGMT expression through interfering with cell signaling pathways.
    Bai P; Fan T; Wang X; Zhao L; Zhong R; Sun G
    Biochem Pharmacol; 2023 Sep; 215():115726. PubMed ID: 37524206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PARP1-MGMT complex underpins pathway crosstalk in O
    Cropper JD; Alimbetov DS; Brown KTG; Likhotvorik RI; Robles AJ; Guerra JT; He B; Chen Y; Kwon Y; Kurmasheva RT
    J Hematol Oncol; 2022 Oct; 15(1):146. PubMed ID: 36242092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
    Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
    Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
    [TBL] [Abstract][Full Text] [Related]  

  • 6. O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke.
    Christmann M; Kaina B
    Mutat Res; 2012 Aug; 736(1-2):64-74. PubMed ID: 21708177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
    Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
    DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
    Göder A; Nagel G; Kraus A; Dörsam B; Seiwert N; Kaina B; Fahrer J
    Carcinogenesis; 2015 Aug; 36(8):817-31. PubMed ID: 25998848
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Formation and degradation of nitrogen mustard-induced MGMT-DNA crosslinking in 16HBE cells.
    Cheng J; Ye F; Dan G; Zhao Y; Zhao J; Zou Z
    Toxicology; 2017 Aug; 389():67-73. PubMed ID: 28720507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human variants of O6-alkylguanine-DNA alkyltransferase.
    Pegg AE; Fang Q; Loktionova NA
    DNA Repair (Amst); 2007 Aug; 6(8):1071-8. PubMed ID: 17482892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.
    Hashimoto K; Sharma V; Sasanuma H; Tian X; Takata M; Takeda S; Swenberg JA; Nakamura J
    Oncotarget; 2016 Sep; 7(37):59795-59808. PubMed ID: 27486975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. No-observed effect levels are associated with up-regulation of MGMT following MMS exposure.
    Doak SH; Brüsehafer K; Dudley E; Quick E; Johnson G; Newton RP; Jenkins GJ
    Mutat Res; 2008 Dec; 648(1-2):9-14. PubMed ID: 18992265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MGMT: a personal perspective.
    Mitra S
    DNA Repair (Amst); 2007 Aug; 6(8):1064-70. PubMed ID: 17482889
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy.
    Peng Y; Pei H
    J Zhejiang Univ Sci B; 2021 Jan; 22(1):47-62. PubMed ID: 33448187
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O
    Kraus A; McKeague M; Seiwert N; Nagel G; Geisen SM; Ziegler N; Trantakis IA; Kaina B; Thomas AD; Sturla SJ; Fahrer J
    Arch Toxicol; 2019 Feb; 93(2):559-572. PubMed ID: 30446773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor-associated mutations in O⁶ -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.
    Lamb KL; Liu Y; Ishiguro K; Kwon Y; Paquet N; Sartorelli AC; Sung P; Rockwell S; Sweasy JB
    Mol Carcinog; 2014 Mar; 53(3):201-10. PubMed ID: 23065697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic association and functional studies of major polymorphic variants of MGMT.
    Bugni JM; Han J; Tsai MS; Hunter DJ; Samson LD
    DNA Repair (Amst); 2007 Aug; 6(8):1116-26. PubMed ID: 17569599
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alkylation damage in DNA and RNA--repair mechanisms and medical significance.
    Drabløs F; Feyzi E; Aas PA; Vaagbø CB; Kavli B; Bratlie MS; Peña-Diaz J; Otterlei M; Slupphaug G; Krokan HE
    DNA Repair (Amst); 2004 Nov; 3(11):1389-407. PubMed ID: 15380096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.
    Kaina B
    Cytogenet Genome Res; 2004; 104(1-4):77-86. PubMed ID: 15162018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Temozolomide Sensitizes MGMT-Deficient Tumor Cells to ATR Inhibitors.
    Jackson CB; Noorbakhsh SI; Sundaram RK; Kalathil AN; Ganesa S; Jia L; Breslin H; Burgenske DM; Gilad O; Sarkaria JN; Bindra RS
    Cancer Res; 2019 Sep; 79(17):4331-4338. PubMed ID: 31273061
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.