BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 36693952)

  • 1. The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer.
    Yang X; Cruz MI; Nguyen EV; Huang C; Schittenhelm RB; Luu J; Cowley KJ; Shin SY; Nguyen LK; Lim Kam Sian TCC; Clark KC; Simpson KJ; Ma X; Daly RJ
    Oncogene; 2023 Mar; 42(11):833-847. PubMed ID: 36693952
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers.
    De P; Carlson JH; Jepperson T; Willis S; Leyland-Jones B; Dey N
    Oncotarget; 2017 Jan; 8(2):3072-3103. PubMed ID: 27902969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.
    Lopez-Haber C; Kazanietz MG
    Mol Pharmacol; 2013 May; 83(5):1141-54. PubMed ID: 23478800
    [TBL] [Abstract][Full Text] [Related]  

  • 4. P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells.
    Hampson E; Tsonou E; Baker MJ; Hornigold DC; Hubbard RE; Massey A; Welch HCE
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572121
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear receptor binding protein 1 correlates with better prognosis and induces caspase-dependent intrinsic apoptosis through the JNK signalling pathway in colorectal cancer.
    Liao Y; Yang Z; Huang J; Chen H; Xiang J; Li S; Chen C; He X; Lin F; Yang Z; Wang J
    Cell Death Dis; 2018 Apr; 9(4):436. PubMed ID: 29567997
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration.
    Marei H; Carpy A; Woroniuk A; Vennin C; White G; Timpson P; Macek B; Malliri A
    Nat Commun; 2016 Feb; 7():10664. PubMed ID: 26887924
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
    Lucato CM; Halls ML; Ooms LM; Liu HJ; Mitchell CA; Whisstock JC; Ellisdon AM
    J Biol Chem; 2015 Aug; 290(34):20827-20840. PubMed ID: 26112412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells.
    Thamilselvan V; Gamage S; Harajli A; Chundru SA; Kowluru A
    Cell Physiol Biochem; 2020 Dec; 54(6):1218-1230. PubMed ID: 33347743
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.
    Mishima W; Suzuki A; Yamaji S; Yoshimi R; Ueda A; Kaneko T; Tanaka J; Miwa Y; Ohno S; Ishigatsubo Y
    Genes Cells; 2004 Mar; 9(3):193-204. PubMed ID: 15005707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
    Sosa MS; Lopez-Haber C; Yang C; Wang H; Lemmon MA; Busillo JM; Luo J; Benovic JL; Klein-Szanto A; Yagi H; Gutkind JS; Parsons RE; Kazanietz MG
    Mol Cell; 2010 Dec; 40(6):877-92. PubMed ID: 21172654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
    Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis.
    Li X; Jiang M; Chen D; Xu B; Wang R; Chu Y; Wang W; Zhou L; Lei Z; Nie Y; Fan D; Shang Y; Wu K; Liang J
    J Exp Clin Cancer Res; 2018 Mar; 37(1):71. PubMed ID: 29587866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells.
    Nie B; Cheng N; Dinauer MC; Ye RD
    Cell Signal; 2010 May; 22(5):770-82. PubMed ID: 20074642
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
    Cash JN; Davis EM; Tesmer JJG
    Structure; 2016 May; 24(5):730-740. PubMed ID: 27150042
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.
    Fortin SP; Ennis MJ; Schumacher CA; Zylstra-Diegel CR; Williams BO; Ross JT; Winkles JA; Loftus JC; Symons MH; Tran NL
    Mol Cancer Res; 2012 Jul; 10(7):958-68. PubMed ID: 22571869
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes.
    Balamatsias D; Kong AM; Waters JE; Sriratana A; Gurung R; Bailey CG; Rasko JE; Tiganis T; Macaulay SL; Mitchell CA
    J Biol Chem; 2011 Dec; 286(50):43229-40. PubMed ID: 22002247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesis.
    Wang Z; Dong X; Li Z; Smith JD; Wu D
    Prostaglandins Other Lipid Mediat; 2008 Dec; 87(1-4):9-13. PubMed ID: 18502673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P; Huynh-Do U
    Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.
    Montero JC; Seoane S; Ocaña A; Pandiella A
    Oncogene; 2011 Mar; 30(9):1059-71. PubMed ID: 21042280
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective activation by the guanine nucleotide exchange factor Don1 is a main determinant of Cdc42 signalling specificity in Ustilago maydis.
    Hlubek A; Schink KO; Mahlert M; Sandrock B; Bölker M
    Mol Microbiol; 2008 May; 68(3):615-23. PubMed ID: 18394145
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.